Handbook for Venous Thromboembolism

Handbook for Venous Thromboembolism

A truly practical guidebook for anyone who needs the key information on the diagnosis, management and prevention of venous thromboembolism. Specific areas of focus include understanding the risk factors for VTE and the role... read more

tPA for Critically Ill ICU Patients with COVID-19: Does Alteplase Help?

tPA for Critically Ill ICU Patients with COVID-19: Does Alteplase Help?

How do you define a last-ditch effort to save someone's life from COVID-19? Perhaps giving tPA to a severe COVID patient? At this point, I am certain many of us have attempted, with informed consent of course, therapies for... read more

VTE Diagnosis and Treatment in the COVID-19 Era

VTE Diagnosis and Treatment in the COVID-19 Era

This is a very interesting time to be an intensivist with a research interest in blood clots. As such I wanted to use this time to talk about how COVID 19 has changed our approach to diagnostics, therapeutics and even to... read more

A Rare of Case of COVID-19-Related Pericardial Effusion and Cardiac Tamponade

A Rare of Case of COVID-19-Related Pericardial Effusion and Cardiac Tamponade

Acute pericarditis involves inflammation of the pericardial sac, which is made of an inner mesothelial visceral layer that surrounds the heart. Normally, this layer produces ~50 mL of fluid to lubricate the heart and... read more

Venous Thromboembolism Prophylaxis in Critically Ill Adults

Venous Thromboembolism Prophylaxis in Critically Ill Adults

Among critically ill adults, compared to control, low molecular weight heparin (LMWH) reduces incidence of deep venous thrombosis (DVT) while UFH and mechanical compressive devices may reduce risk of DVT. LMWH is probably... read more

Ground-breaking Research – Venous Thrombosis is Back in Business

Ground-breaking Research – Venous Thrombosis is Back in Business

The primary efficacy outcome was the development of a major venous thromboembolic event such as symptomatic distal or proximal deep-vein thrombosis, asymptomatic deep vein thrombosis, pulmonary embolism or venous thromboembolism–related... read more

Spontaneous Echo Contrast in Venous Ultrasound of Severe COVID-19 Patients

Spontaneous Echo Contrast in Venous Ultrasound of Severe COVID-19 Patients

Initial reports have indicated a higher incidence of venous thromboembolism (VTE) among patients with coronavirus disease 2019 (COVID-19) compared to other critical illnesses. Helms et al. found pulmonary embolisms in 25%... read more

New NICE Guidelines on VTE Management

New NICE Guidelines on VTE Management

In the midst of everything that is going on with COVID-19 it is easy to see how important non coronavirus stuff can get overlooked. But we still need to keep our eyes open. After a 3 year process involving many meetings,... read more

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism

Based on study of more than 28,000 TJA patients, presurgical ABO blood group testing looks like an inexpensive way to identify patents at increased risk for symptomatic postoperative VTE. Prophylaxis regimens can dramatically... read more

Thrombosis and Bleeding in the ICU

Thrombosis and Bleeding in the ICU

ICU patients are high risk of developing thrombotic complications such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Indeed, due to the hypercoagulative state typical for many forms of critical illness associated... read more

EHR-guided Strategy Reduces Postop VTE Events

EHR-guided Strategy Reduces Postop VTE Events

By incorporating algorithms into the electronic health record (EHR), UPMC was able to realize a "dramatic" 72% reduction in missed doses, from 4,331 missed doses in 2014 to 1,193 in 2015, Dr. Neal told attendees in a session... read more

Subsegmental Pulmonary Embolism: Anticoagulation or Observation?

Subsegmental Pulmonary Embolism: Anticoagulation or Observation?

As the use of chest CT-angiograms in emergency departments and medical wards has risen by more than tenfold, so has the discovery of small pulmonary emboli of unclear clinical significance. These PEs are often isolated to... read more

ECMO, An Issue of Critical Care Clinics

ECMO, An Issue of Critical Care Clinics

This issue of Critical Care Clinics focuses on Mechanical Circulartory Support. Editors Nitin Puri and Michael Baram have assembled an expert team of authors on topics such as: History of Extracorporeal Membrane Oxygenation... read more

The YEARS Study – Simplified Diagnostic Management of PE

The YEARS Study – Simplified Diagnostic Management of PE

The clinical diagnosis of pulmonary embolism (PE) can be challenging given its variable presentation, requiring dependence on objective testing. Decision instruments such as PERC and the Wells' score help stratify patients... read more