This study provides new insight into the mechanisms underlying immunocompromise in critical illness and suggests novel avenues for therapy and prevention of nosocomial infection. Critically ill patients are at heightened... read more

This book analyzes and describes the whole spectrum of technical elements related with non-invasive mechanical ventilators technologies, ventilator modes and complementary technologies for correct interpretation and clinical... read more

Patients with coronavirus disease 2019 (COVID-19) can develop acute respiratory distress syndrome (ARDS), which has been linked to poor prognosis and is a major contributor to patient death. A better understanding of the... read more

Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades II or III and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%. A total of 663 patients... read more

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

Quetiapine may decrease mortality and improve neurological outcomes in critically-ill traumatic brain injury (TBI) patients. It has a dose-dependent effect to decrease intracranial pressure (ICP) and increase cerebral perfusion... read more

Automated ventilation (AV) appears to reduce the incidence and severity of blood oxygen desaturation during daily nursing procedures (DNPs) in comparison to Conventional Ventilation (CV). Of the 265 included patients, 93%... read more

Considerations for cardiac imaging in the COVID-19 era include thoughtful patient and study selection with a goal to limit the overall number of tests. General recommendations are as follows: Defer routine or low-risk studies... read more

Targeting moderate sedation (MS) or deep sedation (DS) did not reliably result in the intended sedation level. Targeting MS, however, resulted in a lower rate of total AREs and fewer patients had multiple AREs with no difference... read more

In this preliminary study of patients with sepsis and ARDS, a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers of inflammation and vascular injury.... read more

LANGE Critical Care delivers concise, evidenced-based, and highly clinical coverage of the surgical and medical aspects of critical care. The book provides basic fundamentals, applications and insights that will be of lasting... read more

ICU Doctor Chandar Abboy and his partner came up with a way to give a voice to the voiceless. The app called “Yo Doc” allows patients on ventilators to better communicate their needs and feelings. Dr. Abboy says this... read more

The decision whether to give more fluid during the management of shock can be somewhat provider-dependent. This multicenter prospective cohort study evaluated 1639 patients with hypotension requiring vasopressors. The authors... read more

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners,... read more

We provide early clinical and laboratory data about critical pediatric COVID-19, which suggest a variable disease but generally good outcomes compared with adults. Targets for research include the course of organ failure... read more

COVID-19 related cardiopulmonary failure such as ARDS and cardiogenic shock or massive pulmonary embolism can be successfully supported with ECMO. Judicious patient selection is important to enable maximal benefit and optimized... read more

The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a patient... read more

This book addresses an urgent need, offering an updated, detailed and multidisciplinary review of surgery of the inferior vena cava (IVC). Over the past two decades, tremendous advances have been made in this field and related... read more

A new study documents how 49 of those hospitals reacted, and how those efforts varied. It finds that virtually all hospitals put in place a “no visitors” blanket policy. But 59% of hospitals did allow some exceptions... read more

Moderate to severe anxiety at ICU admission is associated with early occurrence of new organ failure in critically ill patients, independently of respiratory status and severity of critical illness. The causality link could... read more