Our pilot study indicated that intravenous vitamin C did not provide significant decreases in the mean dose or duration of vasopressor infusion. Further research that takes into account the potential impact of intervention... read more

This book describes how to monitor and optimize cardiovascular dynamics using advanced hemodynamic monitoring in perioperative and intensive care medicine. The book outlines basic skills of hemodynamic monitoring, different... read more

Multiple international airway societies have created guidelines for the management of the difficult airway. In critically ill patients, there are physiologic derangements beyond inadequate airway protection or hypoxemia.... read more

In this guide, you will understand how ECGs are performed, what they represent about the heart, and what it means to see something you don’t think is normal. Before you get into the hard stuff—the actual interpretation... read more

The RESCUE-IHCA score can be used by clinicians in real time to predict in-hospital death among patients with in-hospital cardiac arrest (IHCA) who are treated with extracorporeal cardiopulmonary resuscitation (ECPR). A total... read more

Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more

This book, now in its 2nd edition, discusses, explains and provides detailed, up-to-date information on physics applied to clinical practice in anesthesiology and critical care medicine, with the aid of simple examples from... read more

The reported prevalence of CAPA in ICU patients with COVID-19 varies greatly by study and may be related to surveillance protocols and inconsistent definitions which may inflate the prevalence of this complication. Further... read more

Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more

Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more

Adult sepsis survivors experience an increased hazard of major cardiovascular events compared to survivors of a non-sepsis hospitalization. 254,241 adult sepsis survivors were matched to adult survivors of non-sepsis hospitalization... read more

The severity and endotype signatures indicate that distinct immune signatures precede the onset of severe sepsis and lethality, providing a method to triage early sepsis patients. Gene expression signatures were obtained... read more

The book provides a practically focused review of the latest techniques used for hemodynamic assessment in the echocardiography laboratory. It features a methodical case-based approach covering how to measure hemodynamic... read more

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used... read more

This book provides a comprehensive practical guide to the plethora of devices that have been developed to support the failing heart. It features easy to follow clinically relevant guidance on mechanical devices used for improving... read more

Although correlations between treatment policies within domains were found, the failure to cluster hospitals indicates that a specific treatment choice within a domain is not a proxy for other treatment choices within or... read more

Comparison of two pharmacokinetic–pharmacodynamic models of rocuronium bromide during profound neuromuscular block. Our findings indicate that using plasma concentrations of rocuronium bromide estimated with either of the... read more