Incidence of AKI and attributive mortality in ARDS randomized trials

The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more

Tags: AKI, ARDS, ICU, PEEP, study,

Sepsis Management in Resource-limited Settings

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More... read more

Tags: book, infection, resources, sepsis, septic shock,

Sepsis-induced coagulopathy: a matter of timeline

Leone et al. have nicely outlined the most frequent questions about thrombocytopenia in sepsis. Besides thrombocytopenia, sepsis indeed induces numerous pathophysiological changes. Among these, the acute-phase response mediated... read more

Tags: coagulopathy, cytokine, sepsis, thrombocytopenia,

Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections

In this monocentric, retrospective observational cohort study, the incidence of ICU-acquired bacterial BSI was not different between immunocompromised and non-immunocompromised patients. This suggests that the clinical management... read more

Tags: bacteremia, BSIs, ECMO, ICU, infection, mechanical ventilation,

A nomogram predicting pneumonia after cardiac surgery

Three preoperative indicators (age, preoperative malnutrition, diabetes mellitus), one intraoperative indicator (CPB > 135 min) and three postoperative indicators (moderate to severe ARDS, use of ECMO or IABP or CRRT, MV>... read more

Tags: ARDS, CRRT, ECMO, IABP, pneumonia, surgery,

Workbook on Renal Replacement Therapy in ICU (ISCCM)

This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more

Tags: AKI, anticoagulation, book, education, ICU, infection, nephrology, nutrition, RRT,

The role of pleural pressure and airway closure during mechanical ventilation

Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more

Tags: airway, mechanical ventilation, PEEP, study, ventilation,

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to massive... read more

Tags: ECMO, inhibitors, mechanical ventilation, NIV, PEEP, ventilation,

Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease

Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more

Tags: asthma, COPD, infection, pneumonia,

Handbook of Drugs in Intensive Care: An A-Z Guide

Now in its sixth edition, the Handbook of Drugs in Intensive Care is the essential guide to using drugs safely and effectively in the intensive care setting. The book is split into two sections: an A-Z guide to the drugs... read more

Tags: book, education, guidelines, ICU, opioids, renal failure,

Two weaning strategies for NIV in COPD patients with ARF

Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more

Tags: ARF, COPD, COVID-19, mechanical ventilation, NIV, study, ventilation,

Improving Outcomes in Nosocomial Pneumonia

Nosocomial pneumonia (NP) represents a leading nosocomial infection and results in substantial morbidity and cost. Over the last several years, the evidence has evolved which directs our approach to NP. Specifically, the... read more

Tags: COVID-19, ECMO, HAP, phenotypes, pneumonia, VAP,

Oxford Textbook of Advanced Critical Care Echocardiography

Advanced critical care echocardiography brings many benefits to critical care medicine. For those wishing to practice echo at a more advanced level, it is necessary to master the theoretical aspects. The Oxford Textbook of... read more

Tags: book, echocardiography, education, training,

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Tags: ECMO, ICU, intubation, SBT, ventilation,

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced thrombocytopenia (HIT) is a serious iatrogenic complication of heparin treatments. The diagnosis of HIT is difficult in the intensive care setting because thrombocytopenia is a frequent and multifactorial...

Case Files Critical Care (LANGE Case Files)

Experience with clinical cases is key to mastering the art and science of medicine and ultimately to providing patients with competent clinical care. Case Files: Critical Care provides 42 true-to-life cases that illustrate...