The early use of neuromuscular blocking agents in the setting of moderate-to-severe acute respiratory distress syndrome (ARDS) was previously understood to confer a survival advantage at 90 days, based on the outcomes of... Read More

This book describes current, evidence-based guidelines for damage control interventions across the field of trauma care with the aim of enabling clinicians to apply them to best effect in daily clinical practice. Emphasis... Read More

Recent studies suggest that hypotension thresholds in current guidelines might be too low for older patients due to arterial stiffening, possibly leading to insufficient fluid resuscitation. We compared intravenous (IV) fluid... Read More

This volume provides a comprehensive summary of the field, with expert recommendations on prediction and management. It details the recent consensus guidelines (2012) updating the definition of pancreatitis and its complications.... Read More

Your Must-Have Guide for Navigating the ICU The House Officer’s Guide to ICU Care is an eminently practical handbook for junior house officers, medical students, PAs, and nurses that offers nuts-and-bolts guidelines... Read More

In this systematic review that included 93 reports of Randomized Clinical Trials (RCTs) from 6 high-impact journals, positive spin of statistically nonsignificant primary outcomes was found in 57% of abstracts and 67% of... Read More

Angiotensin II has been studied for many years and has consistently shown to increase MAP. This medication adds a new mechanism of action to the vasopressor arsenal that is already used for septic shock. Angiotensin II should... Read More

Lower pH after out-of-hospital cardiac arrest (OHCA) has been associated with worsening neurologic outcome, with... Read More

With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe’s Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and... Read More

The AACN Procedure Manual for High Acuity, Progressive, and Critical Care, 7th Edition, authored by the American Association of Critical-Care Nurses, is the authoritative reference to procedures performed in high acuity,... Read More

Objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly... Read More

Cardiogenic shock (CS) is a multifactorial and hemodynamically diverse high-acuity illness that is frequently associated with multisystem organ failure. The complexity of CS requires a widespread application of best-care... Read More

Nosocomial pneumonia is a common hospital-acquired infection and has a high mortality rate in the critically ill. Because drug-resistant bacteria like Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus... Read More

The French Society of Pharmacology and Therapeutics (SFPT) and the French Society of Anesthesia and Intensive Care Medicine (SFAR) have released guidelines on the optimization of beta-lactam treatment in intensive care unit... Read More

Sepsis is medicine’s last remaining preserve for unrestrained antibiotic prescribing. The Surviving Sepsis Campaign guidelines recommend empirical broad-spectrum therapy within one hour of triage for both sepsis and septic... Read More