Helmet CPAP as NIV for COVID-19 Patients
The COVID-19 pandemic has challenged healthcare systems globally, highlighting the need for effective respiratory support strategies. Helmet continuous positive airway pressure (CPAP) has emerged as a potential noninvasive... read more
Tracheostomy in COVID-19 Patients
Tracheostomy is common in critically ill COVID-19 patients. In patients predicted to need a tracheostomy at some point, early, rather than late, tracheostomy might be a means to reduce the time spent in ICU. However,... read more
Pirfenidone to Prevent Fibrosis in ARDS
Pulmonary fibrosis is a major complication of the Acute Respiratory Distress Syndrome (ARDS). Pirfenidone is an approved treatment for idiopathic pulmonary fibrosis. It may attenuate ARDS-related fibrosis and decrease the... read more
Association Between Osteopontin and Apolipoprotein E gene Polymorphisms and Vancomycin-induced AKI
Individuals carrying specific genotypes of APOE (e2e3) were more prone to develop vancomycin-induced acute kidney injury (AKI), per se. This could apply to other nephrotoxic agents as well. We also observed a significant... read more
Severe COVID-19 Early Identification and the Need for ICU Care Based on Objective Risk Factors
The study found that several factors, including advanced age; male gender; and comorbid conditions like diabetes, chronic lung disease, and CVD had a strong association with ICU admission among COVID-19 patients. Similarly,... read more
Point-of-Care Ultrasound for the Neonatal and Pediatric Intensivist: A Practical Guide on the Use of POCUS
This book, written by internationally renowned experts, is a comprehensive text covering all aspects and recommendations regarding the use of POCUS for critically ill neonates and children. Point of Care Ultrasound (POCUS)... read more
Septic Distributive Shock: Resuscitative Endovascular Balloon Occlusion of the Aorta
Massive distributive shock can lead to total collapse of the cardiopulmonary system with a subsequent need for CPR. Partial REBOA may be a viable resuscitation adjunct in such cases to restore hemodynamics and increase coronary... read more
ISCCM Manual of RRT and ECMO in ICU: A Reference Book for Practicing Intensivists
The topics were chosen to make the reader understand comprehensive management of therapies including organization, communication and other administrative issues including cost-effective therapies. This will help the practicing... read more
Lactate Trajectory Models for Predicting AKI and Mortality in Hyperlactatemia Patients
The present study underscores the significant prognostic value of lactate trajectories in critically ill patients, particularly those with hyperlactatemia. Our findings suggest that rapid lactate clearance is strongly... read more
Mortality Time Frame Variability in Septic Shock Clinical Trials
There was considerable variability in the mortality time frames reported in ICU-based septic shock trials. This variability may lead to under or overestimation of the problem, overlooking the effectiveness of the interventions... read more
Hemophagocytic Lymphohistiocytosis Markers Associated with Mortality in Critically Ill Patients
The present study highlights the prognostic significance of HLH criteria in critically ill patients. Individuals exhibiting two or more criteria at ICU admission experienced nearly a doubling in mortality as compared to patients... read more
Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide
This book provides a comprehensive overview on sedation and analgesia for the pediatric intensivist. Divided into two primary sections, the text presents a framework on how to care for patients who need sedation, analgesia,... read more
COVID-19 vs non-COVID-19 Patients Without Hematological Malignancies Treated for Invasive Pulmonary Aspergillosis
COVID-19-associated pulmonary aspergillosis (CAPA) patients have less comorbidities and higher fungal burden compared to Putative Invasive Pulmonary Aspergillosis (PIPA), but clinical outcomes are similar between groups.... read more
Echocardiography for Intensivists
This book contains all the information that readers will require in order to perform echocardiography and to interpret the findings correctly. After an introductory chapter on the essential physics of ultrasonography,... read more
Clinical Prediction Model Development for Stages of AKI in Critically Ill Patients
Using readily available predictors in the ICU setting, we could develop a prediction model for different stages of AKI with good performance and promising clinical usefulness. Among critically ill patients, acute kidney... read more
Provocative Angiography Safety and Efficacy for Gastrointestinal Hemorrhage Localization and Treatment
This study demonstrated that provocative angiography was safe and effective for localization of intermittent or occult gastrointestinal bleeding. Overall, provocative angiography had a positivity rate of 14/40 (35 %) in this... read more
Bedside Procedures in the ICU
This handbook is a guide to best practice in interventions commonly encountered in the ICU. It is clinically orientated providing step-by-step explanations and illustrations of most invasive procedures, check lists to make... read more
Total Bilirubin as a Marker for Hemolysis and Outcome in ARDS Patients Treated with vvECMO
Patients with acute respiratory distress syndrome (ARDS), treatment with veno-venous ECMO and a total bilirubin (tBili) plasma concentration over the threshold of 3.6 mg/dl had significantly lower chances of survival, recovery... read more
The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals
An indispensable resource for physicians, nurse practitioners, physician assistants, pharmacists, and nurses in managing critically ill patients. This comprehensive guide delves deep into the world of vasopressors and inotropes,... read more
COVID-19 Omicron: Immunocompromised vs. Non-immunocompromised Patients
Immunocompromised patients admitted to the ICU due to COVID-19 during the omicron period had higher mortality than non-immunocompromised patients. Additionally, immunocompromised patients with COVID-19 had higher mortality... read more
Airflow Patterns and Adaptive Attachment Ventilation with Deflectors
A novel ventilation mode was introduced and investigated by a series of experiments under isotherm condition, focusing on elucidating the airflow patterns and characteristics associated with this mode. Semi-empirical equations... read more
Diagnostic Value of Chest X-ray in Acute Pulmonary Thromboembolism
This case underscores the diagnostic value of chest X-ray in acute pulmonary thromboembolism (PTE), highlighting the significance of recognizing classical radiographic signs such as Westermark's, Palla's, Fleischner's and... read more
