Successful Clearance of Persistent Staphylococcus Aureus Pneumonia Using High-dose Continuous Infusion Cefazolin

High-dose cefazolin (10 g daily), given as a continuous infusion (CI), was able to clear community-acquired methicillin-susceptible Staphylococcus aureus (MSSA) pneumonia while not exhibiting any signs of toxicity or adverse... read more

VAP in Patients with Increased Intra-abdominal Pressure

Critically ill patients with increased intra-abdominal pressure (IAP) and multidrug-resistant (MDR) ventilator-associated pneumonia (VAP) are considered a challenging patient population in every ICU setting. Patients with... read more

Bedside Procedures for the Intensivist

Bedside Procedures for the Intensivist delivers practical tips and clear, step-by-step instruction on the most common procedures in the ICU. The convenient and portable handbook focuses on ultrasound-guided techniques, including... read more

Bedside Procedures for the Intensivist

Prophylactic IV Antibiotics Outcomes in Patients with Acute Severe Brain Injury on Mechanical Ventilation

Among critically ill patients with acute brain injury, prophylactic IV antibiotics were associated with less VAP but not with changes in length of stay, mortality, or neurologic outcomes. Patients with structural brain... read more

Endovascular Resuscitation and Trauma Management

This book focuses on endovascular methods for resuscitation and trauma management. Written by highly qualified and clinically active physicians from around the world, it shares information gathered over the past decade,... read more

Endovascular Resuscitation and Trauma Management

Management of Pediatric Septic Shock with Electrocardiometry

Advanced hemodynamic monitoring with EC, in conjunction with clinical assessment, facilitated a restrictive fluid strategy and reduced the incidence of FO. By closely monitoring hemodynamic parameters and tailoring therapy... read more

TNF-α, PCT, IL-8, and HBP Prognostic Value Combined with APACHE II Score in Sepsis Patients

Serum TNF-α, PCT, IL-8, and HBP levels influenced sepsis patient prognosis, and their combined detection with APACHE II score provided a high predictive value for patient outcomes. Patients were divided into sepsis and... read more

Association Between Ketamine Use and Mortality in Critically Ill Patients Receiving Mechanical Ventilation

In this retrospective study, we observed that younger patients with acute respiratory distress syndrome (ARDS) may benefit from ketamine use in terms of 14-day mortality. However, these benefits were not observed in longer-term... read more

Pulmonary Hypertension: Controversial and Emerging Topics

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more

Pulmonary Hypertension: Controversial and Emerging Topics

Accurate Percutaneous Tracheal Tube Placement Using Visual-Guided Transillumination Method

The novel Illuminated Tracheal Alignment Guide (iTAG) device and technique is the first of our knowledge to test the identification of tracheostomy sites by way of laser-guided transillumination. We believe this device... read more

Predicting Renal Outcomes in Cardiac Surgery Using Intraoperative Renal Near-Infrared Spectroscopy Monitoring

This study shows that intraoperative monitoring of near-infrared spectroscopy (NIRS) values and monitoring of critical thresholds may be an important tool in predicting the development of acute renal failure (ARF) and other... read more

Peritoneal Dialysis in AKI: 20 Years of Experience at a Single Center

Peritoneal dialysis (PD) may be an effective solution for acute kidney injury (AKI) patients, allowing adequate metabolic and fluid control. Age, APACHE score, hepatorenal syndrome and dropout from PD were associated... read more

Moderate and Deep Sedation in Clinical Practice

Millions of procedures requiring sedation are performed each year, covering a large array of medical specialties in both inpatient and outpatient settings. This tremendous growth has led to sedation being administered by... read more

Moderate and Deep Sedation in Clinical Practice

Flow Control Ventilation in ICU

Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to... read more

Dexmedetomidine for Sedation in Pediatric ICU

Audit shows compliance to the standards were not met. A third of the patients required higher doses of up to 2 micrograms/kg/hour of dexmedetomidine. Studies have supported the safety of higher doses of up to 2 micrograms/kg/hour.2... read more

Imaging the ICU Patient

Work in intensive care is dynamic and often requires swift decision-making to achieve the best patient outcome. This book serves as a practical guide for professionals working in this demanding area of medicine. It reviews... read more

Imaging the ICU Patient

ICU-acquired Weakness: Critical Illness Myopathy and Polyneuropathy

Critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) are significant complications in intensive care unit (ICU) patients, first identified in the late 20th century. These conditions often present... read more

Weaning Failure From Mechanical Ventilation

Ultrasound is a useful tool for identifying weaning failure from cardiovascular, diaphragmatic, respiratory, and airway origin. The strengths of our scoping review lie in its comprehensive approach to synthesizing diverse... read more

Pulmonary Hypertension: Basic Science to Clinical Medicine

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles... read more

Pulmonary Hypertension: Basic Science to Clinical Medicine

Peripheral and Respiratory Muscle Weakness and Functional Impairments in ICU Patients

This study demonstrated that patients discharged from ICU in this resource-constrained setting presented with peripheral and respiratory muscle weakness at unit discharge. Muscle weakness occurred despite a short ICU... read more

Monitoring Mechanical Ventilation Using Ventilator Waveforms

This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes... read more

Monitoring Mechanical Ventilation Using Ventilator Waveforms

Massive Pulmonary Embolism with Clot in Transit Using Fluoroscopic and Transthoracic Echocardiographic-Guided Large-Bore Mechanical Thrombectomy

Massive pulmonary embolism (PE) is a life-threatening condition caused by the obstruction of pulmonary arteries requiring precise and timely intervention to prevent mortality. Clots in transit (CIT), which are thrombi... read more