Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure
Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce... read more
Mitral Valve Transcatheter Edge-to-Edge Repair (MV-TEER) in Patients with Secondary Mitral Regurgitation Improves Hemodynamics, Enhances Renal Function, and Optimizes Quality of Life in Patients with Advanced Renal Insufficiency
Secondary mitral regurgitation (MR) is a common valvular heart disease burdening the prognosis of patients with co-existing chronic heart failure. Transcatheter edge-to-edge mitral valve repair (MV-TEER) is a minimally... read more
Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection
The results of this study indicate that surgical intervention has a significant effect on improving patients’ hemodynamic parameters, with postoperative MAAD and LVEDd reduced compared to preoperative levels, while LVEF... read more
Implementing a Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy Team Reduces Length of Stay and Hospital Costs
Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more
Predictors of Weaning Failure in Ventilated ICU Patients
Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more
Risk Factors for Secondary Organizing Pneumonia and Acute Fibrinous and Organizing Pneumonia in Patients with COVID-19 Pneumonia
Based on our findings, we observed that age ≥50 years, diabetes mellitus, and severe hypoxemia on admission (SpO2 ... read more
Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19
Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more
Skin Decontamination to Prevent ICU Infections
Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently... read more
Septic Shock in the Prehospital Setting
Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more
Evidence-Based Critical Care
This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new... read more
The Pathophysiology of Happy Hypoxemia in COVID-19
The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging healthcare systems worldwide. Many patients present with a remarkable disconnect in rest between profound hypoxemia yet without proportional... read more
A Perspective on Post-Cardiac Arrest Syndrome
This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation.... read more
Hypothermic Cardiac Arrest: Prognostic Factors for Successful Resuscitation Before Rewarming
Patients with core body temperature ... read more
Teaching Pearls in Noninvasive Mechanical Ventilation
This book uses real-world clinical case analyses of hot topics to provide insights into noninvasive mechanical ventilation (NIV). Written by leading international teachers and experts, it features a selection of "major... read more
Protocolized Fluid Balance Neutralization During CRRT
Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more
Relationship between Concentrations of Oxygen and Levels of Oxidative Stress in Patients Receiving Oxygen Therapy for Severe COVID-19 Pneumonia
We evaluated the potential of high-flow oxygen therapy to increase oxidative stress and inflammation in COVID-19 patients. Our observation of decreased MDA levels when transitioning hypertensive patients from high-flow to... read more
Preventing VAP Non-Pharmacologically
In critically ill, intubated patients on intensive care unit (ICU), ventilator-associated pneumonia (VAP) is a significant complication contributing to substantial mortality, morbidity, and prolonged stays, which in turn... read more
