TNF-α, PCT, IL-8, and HBP Prognostic Value Combined with APACHE II Score in Sepsis Patients
Serum TNF-α, PCT, IL-8, and HBP levels influenced sepsis patient prognosis, and their combined detection with APACHE II score provided a high predictive value for patient outcomes. Patients were divided into sepsis and... read more
Association Between Ketamine Use and Mortality in Critically Ill Patients Receiving Mechanical Ventilation
In this retrospective study, we observed that younger patients with acute respiratory distress syndrome (ARDS) may benefit from ketamine use in terms of 14-day mortality. However, these benefits were not observed in longer-term... read more
Pulmonary Hypertension: Controversial and Emerging Topics
This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more

Accurate Percutaneous Tracheal Tube Placement Using Visual-Guided Transillumination Method
The novel Illuminated Tracheal Alignment Guide (iTAG) device and technique is the first of our knowledge to test the identification of tracheostomy sites by way of laser-guided transillumination. We believe this device... read more
Predicting Renal Outcomes in Cardiac Surgery Using Intraoperative Renal Near-Infrared Spectroscopy Monitoring
This study shows that intraoperative monitoring of near-infrared spectroscopy (NIRS) values and monitoring of critical thresholds may be an important tool in predicting the development of acute renal failure (ARF) and other... read more
Peritoneal Dialysis in AKI: 20 Years of Experience at a Single Center
Peritoneal dialysis (PD) may be an effective solution for acute kidney injury (AKI) patients, allowing adequate metabolic and fluid control. Age, APACHE score, hepatorenal syndrome and dropout from PD were associated... read more
Moderate and Deep Sedation in Clinical Practice
Millions of procedures requiring sedation are performed each year, covering a large array of medical specialties in both inpatient and outpatient settings. This tremendous growth has led to sedation being administered by... read more

Flow Control Ventilation in ICU
Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to... read more
Dexmedetomidine for Sedation in Pediatric ICU
Audit shows compliance to the standards were not met. A third of the patients required higher doses of up to 2 micrograms/kg/hour of dexmedetomidine. Studies have supported the safety of higher doses of up to 2 micrograms/kg/hour.2... read more
Imaging the ICU Patient
Work in intensive care is dynamic and often requires swift decision-making to achieve the best patient outcome. This book serves as a practical guide for professionals working in this demanding area of medicine. It reviews... read more

ICU-acquired Weakness: Critical Illness Myopathy and Polyneuropathy
Critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) are significant complications in intensive care unit (ICU) patients, first identified in the late 20th century. These conditions often present... read more
Weaning Failure From Mechanical Ventilation
Ultrasound is a useful tool for identifying weaning failure from cardiovascular, diaphragmatic, respiratory, and airway origin. The strengths of our scoping review lie in its comprehensive approach to synthesizing diverse... read more
Pulmonary Hypertension: Basic Science to Clinical Medicine
This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles... read more

Peripheral and Respiratory Muscle Weakness and Functional Impairments in ICU Patients
This study demonstrated that patients discharged from ICU in this resource-constrained setting presented with peripheral and respiratory muscle weakness at unit discharge. Muscle weakness occurred despite a short ICU... read more
Monitoring Mechanical Ventilation Using Ventilator Waveforms
This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes... read more

Massive Pulmonary Embolism with Clot in Transit Using Fluoroscopic and Transthoracic Echocardiographic-Guided Large-Bore Mechanical Thrombectomy
Massive pulmonary embolism (PE) is a life-threatening condition caused by the obstruction of pulmonary arteries requiring precise and timely intervention to prevent mortality. Clots in transit (CIT), which are thrombi... read more
Extubation in the Operating Room After Elective On-pump CABG Surgery
Although immediate extubation in the operating room following on-pump coronary artery bypass graft (CABG) surgery did not show significant differences in ICU or hospital length of stay (LOS), mortality, or ICU readmission... read more
Cytomegalovirus Infection Adverse Impact on ICU Outcomes in COVID-19 Patients
In critically ill patients with SARS-CoV-2 pneumonia, cytomegalovirus (CMV) infection was frequently observed, and associated with increased ICU and hospital mortality. CMV co-infection correlated with a higher incidence... read more
NIV Effectiveness in Critical Patients with ARF and Do Not Intubate Order
The prevalence of do-not-intubate (DNI) order was frequent in patients with acute respiratory failure (ARF) admitted to the ICU, being related to age, comorbidity, frailty and the underlying disease. non-invasive ventilation... read more
Nebulized Furosemide Effect on the Mortality of Mechanically Ventilated ARDS Adult Patients
This RCT tackles an important topic in critical care medicine, which involves a large number of critically ill patients and continues to harbor high mortality despite improvements in management. The results of the study... read more
Reducing Mortality in Critically Ill Patients
This book describes the techniques, strategies, and drugs that have been demonstrated by multicenter randomized trials to influence survival in critically ill patients, defined as those who have acute failure of at least... read more

Prophylactic NIV Effects on Weaning
The use of prophylactic non-invasive ventilation (NIV) reduced reintubation rates, ICU and hospital length of stay (LOS), and mortality. These findings support the recommendation for its use in daily practice. Rescue... read more