Delays in ED antibiotic initiation time are associated with clinically important increases in long-term, risk-adjusted sepsis mortality. This study investigated the association of door-to-antibiotic time with long-term mortality... read more

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more

Intravenous fluid administration is an essential component of sepsis management, but a positive fluid balance has been associated with worse prognosis. We analyzed whether a positive fluid balance and its persistence over... read more

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship–the heart of medicine–is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical... read more

Excessive noise in hospitals adversely affects patients’ sleep and recovery, causes stress and fatigue in staff and hampers communication. The World Health Organization suggests sound levels should be limited to 35... read more

Underfeeding in critical illness is common and associated with poor outcomes. Researchers in the UK designed a before-and-after study to evaluate the safety, efficacy and clinical outcomes associated with volume-based feeding... read more

From ER and M*A*S*H to Grey’s Anatomy and House, the medical drama endures for good reason: we’re fascinated by the people we must trust when we are most vulnerable. In Also Human, vocational psychologist Caroline... read more

The optimal securement method of endotracheal tubes is unknown but should prevent dislodgement while minimizing complications. The use of an endotracheal tube fastener might reduce complications among critically ill adults... read more

Welcome to 97-hour weeks. Welcome to life and death decisions. Welcome to a constant tsunami of bodily fluids. Welcome to earning less than the hospital parking meter. Wave goodbye to your friends and relationships. Welcome... read more

A Johns Hopkins-led study on sedation practices in critically ill patients in a resource-limited setting finds that deep sedation, agitation, and benzodiazepines were independently associated with worse clinical outcomes.... read more

This paper justifies utilizing a higher tidal volume strategy for our patients without primary ARDS/pulmonary disease. This can be very useful. Patient comfort and patient-ventilator synchrony are extremely important. This... read more

Following in the wake of hugely successful medical memoirs such as Do No Harm and Fragile Lives, Critical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives... read more

For Matt Morgan, writing is a means to relieve work stress and turn it into something useful. In his first book, which will soon be published with Simon & Schuster, he shares stories from the intensive care unit, one... read more

If you work in healthcare and haven’t read the book “In Shock: My Journey from Death to Recovery and the Redemptive Power of Hope” I really hope you will. In the meantime listen to intensivist and best-selling... read more

An interdisciplinary team of front-line physicians, nurses, medical assistants, and executives assembled and used value stream mapping to assess the entire ED care process, from patient arrival to admission or discharge.... read more

Back when I was in business school, I interviewed for a job at a health care consulting firm. During one of the interviews, a partner there told me that there isn’t too much difference between running a hospital and... read more

Twenty-eight anesthetic events were carried out on 24 free-ranging Scandinavian gray wolves (Canis lupus) by darting from a helicopter with 5 mg medetomidine and 250 mg ketamine during winter in 2002 and 2003. Mean±SD doses... read more

Ranjit Deshpande, MD, and Mark D. Cipolle, MD, PhD, FCCM, discuss Dr. Cipolle’s talk from the 48th Critical Care Congress on what’s new in anticoagulant reversal. Tune in to hear about the hottest topics and current... read more