Tag: research

Upvote Story 5
Among patients with out-of-hospital cardiorespiratory arrest (OHCA), the use of BMV compared with ETI failed to demonstrate noninferiority or inferiority for survival with favorable 28-day neurological function, an inconclusive result. A determination of equivalence or superiority between these techniques requires further research. This study has several limitations. First, the presence of a physician in the ambulance team may make the results of this study less... Read More | Comment
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Among ICU nurses, an intervention that included education, role-play, and debriefing resulted in a lower prevalence of job strain at 6 months compared with nurses who did not undergo this program. Further research is needed to understand which components of the program may have contributed to this result and to evaluate whether this program is cost-effective. Among 198 ICU nurses who were randomized (95 aged... Read More | Comment
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Delirium is a confused mental state that includes changes in awareness, thinking, judgment, sleeping patterns, and behavior. It can affect patients of any age but is more common among older adults who experience major illness or have a major surgery. More than half of patients who are given mechanical ventilation in the intensive care unit (ICU) experience delirium. Antipsychotic medications have been used to treat... Read More | Comment
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This article explores the potential role of nutrition and EMS in maintaining muscle health in critical illness. Within this article, we will evaluate fundamental concepts of muscle wasting and evaluate the effects of EMS, as well as the effects of nutrition therapy on muscle health and the clinical and functional outcomes in critically ill patients. We will also highlight current research gaps in order to... Read More | Comment
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Dr. Sam Parnia, Director of the AWARE Study (AWAreness during REsuscitation) and one of the world’s leading experts on the scientific study of death and near-death experiences (NDE), presents cutting-edge research from the front lines of critical care and resuscitation medicine while also shedding light on the ultimate mystery: What happens to human consciousness during and after death? Dr. Parnia reveals how some form of... Read More | Comment
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Nurse intuition doesn’t sound scientific, but it could play a key role in critical-care outcomes, according to a small study published in DovePress. The researchers conducted a descriptive phenomenological study, interviewing 12 nurses who had at least three years of work experience in critical care units. Due to the small size of the study, more research is needed, However, the results indicate that many nurses... Read More | Comment
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In this compelling episode, Professor Paul Wischmeyer, shares some of his experiences as a patient in the ICU. Since he was 15 he has endured multiple hospitalizations and ICU stays for his inflammatory bowel disease. This has given him an excellent vantage point to notice what we as ICU professionals do and say to our patients. And from Paul’s perspective we could do much better.... Read More | Comment
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In this randomized, double-blind, placebo-controlled, dose-finding adaptive phase 2a/2b trial enrolling 301 adults, the optimal therapeutic dose of recombinant alkaline phosphatase was 1.6 mg/kg. Treatment with this dose for 3 days when added to standard care resulted in a median increase in endogenous creatinine clearance of 27.6 mL/min vs 14.7 mL/min for placebo in the first 7 days, a difference that was not statistically significant.... Read More | Comment
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New research presented at this year’s ESICM LIVES conference (the annual meeting of the European Society of Intensive Care Medicine) shows that in rich countries overall, mortality from sepsis has fallen by around a quarter in men since 1985, with a smaller reduction in women. While some countries (namely, Finland, Iceland, Ireland and New Zealand) have made progress, mortality rates continue to rise in others... Read More | Comment
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Researchers supported by the NIHR have created an artificial intelligence system that could help identify the best way to treat patients with sepsis. The system ‘learnt’ the best treatment strategy for a patient by analysing the records of about 100,000 hospital patients in intensive care units and every single doctor’s decisions affecting them. The technology, developed by researchers at the NIHR Imperial Biomedical Research Centre,... Read More | Comment
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The current conflicts of interest (COIs) disclosure forms of selected professional societies provide more attention to financial disclosures and COIs and less attention to detecting and managing intellectual COIs, while rarely addressing institutional COIs. We provide some suggestions for guideline developers on the classification and management of different COIs in the context of CPGs. All selected professional critical care societies require that members declare direct... Read More | Comment
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A fungus that thrives in dry soil and warm weather has caused a record number of infections in California. Experts fear climate change will cause it to spread across the western US. Valley fever, a fungal disease that infects an estimated 150,000 people in the US each year and has been on the rise in California. Valley fever, also called coccidioidomycosis, is caused by a... Read More | Comment
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The word mentorship evokes strong emotional and intellectual chords. In formal parlance, mentorship has been defined as “a dynamic, reciprocal relationship in a work environment between an advanced-career incumbent (mentor) and a beginner (mentee) aimed at promoting the career development of both.” In our careers in academic medicine, we have seen mentees benefit from mentors through development of critical thinking skills and advice on research... Read More | Comment
Upvote Story 14
A new clinical trial at Emory University and 45 other sites around the U.S. will test a combination of vitamins and steroids in patients diagnosed with sepsis. Sepsis is caused by the body’s overwhelming and life-threatening response to infection that can lead to tissue damage, organ failure and death. According to sepsis researchers, sepsis can account for 30 to 50 percent of all hospital deaths,... Read More | Comment
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The consequences of burning out — a phenomenon that rises linearly as a doctor matures, until it finally dies down at about 60 — can be hard to measure. Some solutions to fixing burnout are therefore pragmatic. They involve lessening burdens: removing paperwork that does not positively affect patient care, lightening bureaucracies and dissolving the form-filling, diagnosis-coding, button-pushing culture of modern medicine. We survived, I... Read More | Comment