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Sedation in ICU patients – Need for Standardized Protocols

Sedation in ICU patients – Need for Standardized Protocols

A Johns Hopkins-led study on sedation practices in critically ill patients in a resource-limited setting finds that deep sedation, agitation, and benzodiazepines were independently associated with worse clinical outcomes. The study’s main objective was to determine the relationship between sedation status and 90-day mortality. Study results show that a greater percentage of days spent in deep sedation was associated with a fivefold greater odds of mortality, while agitation status had a 40-fold higher mortality; benzodiazepine usage was associated with a 41% higher odds of 90-day mortality. The results indicate that despite strong evidence that correlates sedation depth with worse clinical outcomes, most ICU patients were deeply sedated during their ICU stay.

CriticalCare.news
May 8, 2019

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