Among adult patients with cardiac arrest, the use of targeted temperature management at 32–34 °C, when compared to normothermia, did not result in improved outcomes in this meta-analysis. There was no effect of initiating... read more

This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more

Rhythm check three – A2BCDE3! – A new acronym to select eligible patients for extracorporeal cardiopulmonary resuscitation (eCPR) Extracorporeal cardiopulmonary resuscitation (eCPR) is an ultra-invasive approach... read more

Who says understanding ventilator modes has to be hard? This book gives you easy to understand information that every RRT, RN, or Resident always wishes they had. Each mode is described in simple language and answers the... read more

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January 2021.... read more

Pulmonary Embolism (PE) patients with hypocalcemia have higher in-hospital mortality than those without hypocalcemia. The in-hospital complications were also higher, along with longer length of stay. In the 2017 NIS, 187,989... read more

Although corticosteroid administration has been associated with improved outcomes in severe COVID-19 pneumonia, their ideal use remains undefined with a “one size fits all” approach used, irrespective of the individual... read more

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Rates of survival with functional recovery for both in-hospital and out-of-hospital cardiac arrest are notably low. Extracorporeal cardiopulmonary resuscitation (ECPR) is emerging as a modality to improve prognosis by augmenting... read more

Increased recognition of the overlap between critical care and renal medicine, and recent advances in the understanding of acute renal failure (ARF) and the application of renal replacement therapies (RRTs), have brought... read more

Small caliber 14-Fr PCs are equally as effective as 28- to 32-Fr chest tubes in their ability to drain traumatic HTX with no difference in complications. Patients reported better IPE scores with PCs over chest tubes, suggesting... read more

Fluid overload in acute respiratory distress syndrome is associated with increased mortality. The purpose of this study was to investigate the association of cumulative fluid balance (CFB) during the first 7 days of eno-venous... read more

Thrombotic complications (arterial and venous) are common in patients admitted to hospital with COVID-19 and are an independent predictor of poor outcome. Microvascular thrombi also contribute to organ dysfunction, including... read more

Mechanical energy (ME) better related to underlying lung pathology and patient outcome than MP. The delivery of generated energy to the lung was not dependent on endotracheal tube diameter (ETT) size during PC ventilation.... read more

Vitamin C monotherapy failed to significantly reduce mortality in septic shock patients as hypothesized. Our findings do not support its routine clinical use for this purpose. Of 124 subjects receiving study drug and included... read more

This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners. The major... read more

In its most basic sense, the physical exam is a method of inferring the state of health of the internal organs. For two centuries, it has been accomplished through auscultation, inspection, palpation, and percussion. These... read more

Excessive inflammation drives the progression from sepsis to septic shock. Macrophage migration inhibitory factor (MIF) is of interest because MIF promoter polymorphisms predict mortality in different infections, and anti-MIF... read more