COVID-19 Critical and Intensive Care Medicine Essentials

COVID-19 Critical and Intensive Care Medicine Essentials

This book provides healthcare professionals in Critical Care setting an easy consultation guide to fight against COVID-19. The book is divided into sections: Fundamentals of COVID-19, Pneumological critical care, Neurological... read more

High Flow Nasal Cannula: Physiological Effects and Clinical Applications

High Flow Nasal Cannula: Physiological Effects and Clinical Applications

This book presents the state of the art in high-flow nasal cannula (HFNC), an oxygen therapy technique that has recently proven to be a very promising approach to supporting respiratory function in several medical fields. In... read more

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Remdesivir treatment increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg... read more

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Among hospitalised COVID-19 patients needing oxygen therapy, high dose of dexamethasone reduced clinical worsening within 11 days after randomisation as compared with low dose of dexamethasone. Further studies are necessary... read more

Anti-interleukin Drugs Effect on COVID-19 Patients

Anti-interleukin Drugs Effect on COVID-19 Patients

Drugs targeting IL-1 or IL-6 did not shorten the time to clinical improvement in this sample of patients with COVID-19, hypoxic respiratory failure, low SOFA score, and low baseline mortality risk. Between April 4, and... read more

Interhospital Transfer of COVID-19 Patients Treated with High-flow Nasal Oxygen Therapy

Interhospital Transfer of COVID-19 Patients Treated with High-flow Nasal Oxygen Therapy

At the start of the COVID-19 pandemic, early intubation was recommended on the basis of worldwide observations of severe hypoxemia. However, some patients were ultimately able to benefit from high-flow nasal cannula (HFNC)... read more

RECOVERY-RS trial finds CPAP reduces need for invasive ventilation in hospitalised COVID-19 patients

RECOVERY-RS trial finds CPAP reduces need for invasive ventilation in hospitalised COVID-19 patients

The NIHR-supported Respiratory Strategies in COVID-19; CPAP, High-flow, and Standard Care (RECOVERY-RS) trial has demonstrated that treating hospitalised COVID-19 patients who have acute respiratory failure with continuous... read more

Adaptive Randomized Controlled Trial of Non-invasive Respiratory Strategies in ARF Patients with COVID-19

Adaptive Randomized Controlled Trial of Non-invasive Respiratory Strategies in ARF Patients with COVID-19

Continuous positive airway pressure (CPAP), compared with conventional oxygen therapy, reduced the composite outcome of intubation or death within 30 days of randomisation in hospitalized adults with acute respiratory failure... read more

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, due to the surge of patients requiring advanced respiratory support. Shortage of intensive care unit... read more

An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy

An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy

In patients with pneumonia with acute respiratory failure treated with high-flow nasal cannula (HFNC), ROX is an index that can help identify those patients with low and those with high risk for intubation. This was a... read more

Pharyngeal abscess: a rare complication of repeated nasopharyngeal swabs

Pharyngeal abscess: a rare complication of repeated nasopharyngeal swabs

A 73-year-old end-stage renal disease patient who had undergone craniopharyngioma resection 30 years previously was admitted to hospital after a fall. He developed hospital-acquired laboratory-confirmed SARS-CoV-2 that required... read more

Pre-hospital critical care management of severe hypoxemia in victims of COVID-19

Pre-hospital critical care management of severe hypoxemia in victims of COVID-19

Patients with Covid-19 and severe hypoxemia may pose a considerable challenge for the pre-hospital emergency medical services. Intubation may be associated with a high risk of complications in these patients and should be... read more

Conservative or Liberal Oxygen Therapy in Adults After Cardiac Arrest

Conservative or Liberal Oxygen Therapy in Adults After Cardiac Arrest

Conservative oxygen therapy was associated with a statistically significant reduction in mortality at last follow-up compared to liberal oxygen therapy but the certainty of available evidence was low or very low due to bias,... read more