Coronavirus disease 2019 (COVID-19)-infected pregnant women are at higher risk of intensive care unit (ICU) admission and mechanical ventilation. Because reports describing the clinical course and management of critically... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more

More than 80 years after its first description by Eduard Schott, percussion (fist) pacing remains a little known procedure even though it represents an instantly available and easy to perform treatment for temporary emergency... read more

Current guidelines recommend use of dexamethasone, 6 mg/d, up to 10 days or until discharge for patients hospitalized with COVID-19. Whether patients who received less than 10 days of corticosteroids during hospitalization... read more

Corticosteroids are a class of steroid hormones which are mainly produced in the adrenal cortex of the vertebrates but are also synthesized artificially. They ease redness, itching, swelling and allergic reactions. There... read more

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Pneumonia was the leading cause of death from infectious diseases in the United States, even before the COVID-19 pandemic, and continues to be a leading cause of death. In the study, researchers at Intermountain Healthcare... read more

Patients receiving emergency neurosurgery for traumatic brain injury (TBI) differed considerably in their admission characteristics and management across human development settings. Level of human development was associated... read more

Incidences of inflammatory airway diseases are on the rise across the world. Existing therapeutic options are ineffective, unsafe, and expensive, and severe cases are nonresponsive to conventional therapy. Therefore, it is... read more

The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more

The COVID-19 pandemic has put a spotlight on the devastating global health and societal implications an infection can have when there are no preventative interventions or treatment options available. Many countries and most... read more

Among patients with post-resuscitation shock after out-of-hospital cardiac arrest, use of epinephrine was associated with higher all-cause and cardiovascular-specific mortality, compared with norepinephrine infusion. Until... read more

This issue of Clinics in Chest Medicine, guest-edited by Dr. Gerard Criner and Dr. Bartolome Celli, is focused on Chronic Obstructive Pulmonary Disease. Topics discussed in this issue include but are not limited to: COPD... read more

Thirty-day readmission occurred in 18.4% of patients with acute respiratory distress syndrome (ARDS) in this sample, and early readmission is strongly associated with increased mortality compared to late readmission. Further... read more

An overview of vasopressor management, current evidence and when to initiate vasopressor therapy for best possible patient outcome. Vasopressor management is a cornerstone in the haemodynamic management of septic shock for... read more