ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates

ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates

Accidental hypothermia designates an unintentional drop in body temperature below 35 °C. There is a major risk of ventricular fibrillation below 28 °C and cardiac arrest is almost inevitable below 24 °C. In such cases,... read more

ECPR in 2023

ECPR in 2023

Extracorporeal cardiopulmonary resuscitation (ECPR) is invasive and resource intense. Data suggesting a survival benefit in patients after OHCA and ECPR derive from retrospective registries and meta-analyses. In order to... read more

Mild Hypercapnia or Normocapnia after OHCA

Mild Hypercapnia or Normocapnia after OHCA

In patients with coma who were resuscitated after out-of-hospital cardiac arrest (OHCA), targeted mild hypercapnia did not lead to better neurologic outcomes at 6 months than targeted normocapnia. A total of 1,700 patients... read more

Duration of Device-Based Fever Prevention After Cardiac Arrest

Duration of Device-Based Fever Prevention After Cardiac Arrest

While fever prevention for 72 hours after cardiac arrest has been endorsed by international guidelines since 2005, there is a lack of randomized control trial (RCT) generated data supporting this after the initial 24 hours... read more

Differential Diagnosis and Cause-specific Treatment During OHCA

Differential Diagnosis and Cause-specific Treatment During OHCA

The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more

Emergency vs. Delayed Catheterization in Survivors of OHCA

Emergency vs. Delayed Catheterization in Survivors of OHCA

In this randomized clinical trial, for patients who experience an out-of-hospital cardiac arrest (OHCA) without ST-segment elevation on ECG, a strategy of emergency CAG was not better than a strategy of delayed CAG with respect... read more

Inhaled Hydrogen Efficacy on Neurological Outcome Following Brain Ischemia During Post-cardiac Arrest Care

Inhaled Hydrogen Efficacy on Neurological Outcome Following Brain Ischemia During Post-cardiac Arrest Care

Inhaled molecular hydrogen gas (H2) has been shown to improve outcomes in animal models of cardiac arrest (CA). H2 inhalation is safe and feasible in patients after CA. We investigated whether inhaled H2 would improve outcomes... read more

COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

While other international studies have observed higher incidence and reduced survival in non-EMS-witnessed out-of-hospital cardiac arrest (OHCA) during the COVID-19 pandemic, this study did not identify any significant impacts... read more

IHCA Variation Throughout the Day

IHCA Variation Throughout the Day

We observed higher rates of hospital cardiac arrest (IHCA), and poorer outcomes at night. However, in those admitted to ICU, this variation was absent. This suggests patient factors and processes of care issues contribute... read more

Improving Access to ECMO for OHCA

Improving Access to ECMO for OHCA

Mobile teams using transport accessibility frameworks and principles can significantly improve patient access for out-of-hospital cardiac arrest (OHCA) compared to in-hospital extracorporeal cardiopulmonary resuscitation... read more

Expert Consensus on PeRcutaneous Cannulation for ECPR

Expert Consensus on PeRcutaneous Cannulation for ECPR

We present inclusion and exclusion criteria and a comprehensive, detailed, generalizable list of best practices for extracorporeal cardiopulmonary resuscitation (ECPR) initiation following refractory out-of-hospital cardiac... read more

Pulse Oximetry Waveform: A Non-invasive Physiological Predictor for the ROSC During CPR

Pulse Oximetry Waveform: A Non-invasive Physiological Predictor for the ROSC During CPR

Pulse oximetry plethysmography (POP) may be a novel and effective method for predicting return of spontaneous circulation (ROSC) during resuscitation, with a prognostic value similar to ETCO2 at early stage. 150 out-of-hospital... read more

Epinephrine vs. Norepinephrine in Cardiac Arrest Patients with Post-resuscitation Shock

Epinephrine vs. Norepinephrine in Cardiac Arrest Patients with Post-resuscitation Shock

Among patients with post-resuscitation shock after out-of-hospital cardiac arrest, use of epinephrine was associated with higher all-cause and cardiovascular-specific mortality, compared with norepinephrine infusion. Until... read more

Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome

Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome

Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and invasive assessment and treatment did not significantly improve... read more