Predictors of Weaning Failure in Ventilated ICU Patients

Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more

Tags: ICU, mechanical ventilation, research, study, ventilator, weaning,

Teaching Pearls in Noninvasive Mechanical Ventilation

This book uses real-world clinical case analyses of hot topics to provide insights into noninvasive mechanical ventilation (NIV). Written by leading international teachers and experts, it features a selection of “major... read more

Tags: book, education, mechanical ventilation, NIV, ventilation,

Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure

Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce the... read more

Tags: AHRF, ARDS, hypoxemia, ICU, LOS, mechanical ventilation, PEEP, study, ventilation,

Septic Shock in the Prehospital Setting

Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more

Tags: diagnosis, hypoperfusion, hypovolemia, lactate, oxygenation, perfusion, sepsis, septic shock, study, vasodilation, vasopressors,

A Perspective on Post-Cardiac Arrest Syndrome

This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation.... read more

Tags: book, cardiology, ischemia, neurology, resuscitation,

Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19

Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more

Tags: ARDS, ARF, COVID-19, mechanical ventilation, oxygenation, proning, research, study,

Risk Factors for Secondary Organizing Pneumonia and Acute Fibrinous and Organizing Pneumonia in Patients with COVID-19 Pneumonia

Based on our findings, we observed that age ≥50 years, diabetes mellitus, and severe hypoxemia on admission (SpO2... read more

Tags: AKI, COVID-19, hypoxemia, infection, pneumonia, pulmonary embolism, study,

Skin Decontamination to Prevent ICU Infections

Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently... read more

Tags: bacteremia, hygiene, ICU, infection, research, study,

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

Tags: book, education, mechanical ventilation, oxygenation, ventilation, ventilator,

Hypothermic Cardiac Arrest: Prognostic Factors for Successful Resuscitation Before Rewarming

Patients with core body temperature ... read more

Tags: cardiac arrest, CPR, hypothermia, oxygenation, resuscitation,

The Pathophysiology of Happy Hypoxemia in COVID-19

The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging healthcare systems worldwide. Many patients present with a remarkable disconnect in rest between profound hypoxemia yet without proportional... read more

Tags: ARDS, COVID-19, hypoxemia, oxygenation, ventilator,

Implementing a Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy Team Reduces Length of Stay and Hospital Costs

Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more

Tags: ICU, LOS, research, study, tracheostomy, ultrasound, ventilator,

Preventing VAP Non-Pharmacologically

In critically ill, intubated patients on intensive care unit (ICU), ventilator-associated pneumonia (VAP) is a significant complication contributing to substantial mortality, morbidity, and prolonged stays, which in turn... read more

Tags: guidelines, ICU, infection, nutrition, oxygenation, pneumonia, VAP, ventilation,

Protocolized Fluid Balance Neutralization During CRRT

Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more

Tags: AKI, CRRT, hemodynamics, hypotension, oxygenation, study, therapy, trial, vasopressors,

Evidence-Based Critical Care

This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new... read more

Tags: analysis, book, education, ICU, monitoring,

Relationship between Concentrations of Oxygen and Levels of Oxidative Stress in Patients Receiving Oxygen Therapy for Severe COVID-19 Pneumonia

We evaluated the potential of high-flow oxygen therapy to increase oxidative stress and inflammation in COVID-19 patients. Our observation of decreased MDA levels when transitioning hypertensive patients from high-flow to... read more

Tags: COPD, COVID-19, diabetes, inflammation, oxygen, pneumonia, research, stress, study,

Mitral Valve Transcatheter Edge-to-Edge Repair (MV-TEER) in Patients with Secondary Mitral Regurgitation Improves Hemodynamics, Enhances Renal Function, and Optimizes Quality of Life in Patients with Advanced Renal Insufficiency

Secondary mitral regurgitation (MR) is a common valvular heart disease burdening the prognosis of patients with co-existing chronic heart failure. Transcatheter edge-to-edge mitral valve repair (MV-TEER) is a minimally invasive... read more

Tags: hemodynamics, nephrology, perfusion, prognosis, renal failure,

Graceful Exit: How to Advocate Effectively, Take Care of Yourself, and Be Present for the Death of a Loved One

When we are thrust into the role of caregiver for a loved one who is in the process of dying, it’s easy to get overwhelmed. Yet it’s a situation millions of us face every year with virtually no sort of preparation...

Targeting Cellular Signalling Pathways in Lung Diseases

The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies...