Plasma Proteome Temporal Changes Associated with Sepsis Mortality

Our proteomics approach revealed significant associations between changes in the plasma proteome within the first days of sepsis and mortality as well as disease severity. We identified and characterised the underlying protein... read more

Tags: COVID-19, diagnosis, ICU, mortality, research, sepsis, SOFA, study,

The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals

An indispensable resource for physicians, nurse practitioners, physician assistants, pharmacists, and nurses in managing critically ill patients. This comprehensive guide delves deep into the world of vasopressors and inotropes,... read more

Tags: book, education, hemodynamics, monitoring, shock, vasopressors,

50 Landmark Papers Every Intensivist Should Know

This book identifies the key scientific articles in the field of Intensive Care and explains why these papers are important in contemporary clinical management. Identifying those influential contributors who have shaped the... read more

Tags: book, education, ICU,

Multidisciplinary Collaborative Bundled Care Improves Outcomes in ICU Patients with Endotracheal Intubation

Multidisciplinary analgesic and sedative bundled care has demonstrated the potential to decrease restraint use in patients undergoing endotracheal intubation and mechanical ventilation, reduce the need for analgesic and sedative... read more

Tags: ICU, intubation, MDT, mechanical ventilation, recovery, research, sedation, ventilation,

Extubation Failure Risk Prediction Model Using Bedside Ultrasound

We have established a risk prediction model for extubation failure in mechanically ventilated ICU patients. This risk model base on bedside ultrasound parameters provides valuable insights for identifying high-risk patients... read more

Tags: extubation, ICU, mechanical ventilation, technology, ultrasound, ventilation,

Evaluation Effects of Nebulized Hypertonic Saline and Nebulized Corticosteroids in Patients with ARDS

Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute respiratory failure as a result of diffuse lung inflammation and oedema manifested by hypoxemia and stiffness in the lungs. This study aimed... read more

Tags: ARDS, corticosteroids, hypoxemia, ICU, inflammation, mechanical ventilation,

Corticosteroid Therapy and Pulmonary Embolism in Polytrauma Patients

Pulmonary embolism is a frequent complication in polytrauma patients. The aim of our study was to evaluate the effect of low-dose corticosteroid therapy on the incidence of pulmonary embolism (PE) in polytrauma patients.... read more

Tags: book, corticosteroids, hydrocortisone, ICU, pulmonary embolism, study,

Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department

Almost 30 million people are affected, and 3 million deaths happen every year because of sepsis. According to WHO’s (World Health Organization) Global Report on Epidemiology and Burden of Sepsis report 2020, half of... read more

Tags: book, education, epidemiology, prognosis, sepsis, septic shock,

Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication

We successfully treated this patient using ECMO and independent lung ventilation. Several cases have been described in the literature, but the pathogenesis and risk factors of UPE remain unclear. Management depends on the... read more

Tags: ECMO, ICU, mechanical ventilation, PEEP, pulmonary edema, surgery, transplantation, treatment, weaning,

ECMO vs. Cardiopulmonary Bypass in Lung Transplantation

Extracorporeal membrane oxygenation (ECMO) offers perioperative advantages in lung transplantation, reducing postoperative complications, one-year mortality, and recovery time compared to CPB. However, the longer total ischemic... read more

Tags: CPB, ECMO, ICU, lungs, stroke, study, thromboembolism,

Strong Ion Difference to Predict Mortality in Septic Shock: Mortality Prediction Model for Admission and 24-hour Mortality

Stewart’s model examines the relationship between the movement of ions across biological membranes and the consequent changes in pH related to modifications in three dependent variables which are the strong ion difference... read more

Tags: book, education, research, sepsis, septic shock,

72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy

Acute respiratory failure (ARF) is common in critically ill patients, and 50% of patients in intensive care units require mechanical ventilation. The COVID‐19 pandemic revealed that COVID‐19 infection induced ARF caused... read more

Tags: ARF, COVID-19, infection, infusion, mechanical ventilation, pneumonia, trial, ventilation,

Predictors of Functional Impairment in Severe COVID-19 Patients Two Months After Discharge

The Post-COVID-19 Functional Status (PCFS) scale is a validated tool for assessing functional impairment in COVID-19 patients. While this retrospective monocentric study identified multiple risk factors associated with high... read more

Tags: corticosteroids, COVID-19, discharge, hydrocortisone, rehabilitation, study, thrombolytics,

The Beginner’s Guide to Intensive Care: A Handbook for Junior Doctors and Allied Professionals

Ideal for any medic or health professional embarking upon an intensive care rotation or specialism, this simple bedside handbook provides handy, pragmatic guidance to the day-to-day fundamentals of working in an intensive... read more

Tags: ARDS, book, education, ICU,

Ketamine May Reduce Opioid Requirements Following Cardiac Surgery

Ketamine may be a reasonable choice for postoperative cardiac surgery analgesia and may reduce the need for opioids on discharge, and possibly during admission. This study is a single center, retrospective, observational,... read more

Tags: analgesia, cardiology, ketamine, opioids, sedation, study, surgery,

Fast-Track in Cardiac Anesthesia: Cardiac Surgery in the Era of ERAS

This new book, focused on fast-track approaches in cardiac surgery, covers ERAS cardiac guidelines, explores the application of loco-regional anesthesia in cardiac surgery, and addresses all aspects related to early extubation... read more

Tags: anesthesia, book, extubation, guidelines, ICU, opioids, pain, surgery,

Succinate-containing Crystalloid Solution in Correction of COVID-19-associated Endotheliopathy

The use of a succinate-containing infusion solution in patients with a new coronavirus infection promotes a more rapid and sustainable correction of COVID-19-associated endotheliopathy, which, in turn, is manifested by a... read more

Tags: COVID-19, endotheliopathy, infusion, study,

Management of Pain, Anxiety, and Delirium in Critically Injured Pediatric Trauma Patients

PICU-specific care bundles have been beneficial in standardizing the assessment, prevention and treatment of pain, anxiety and delirium. While these practices show promise in addressing current management challenges in pediatric... read more

Tags: anxiety, delirium, pain, pediatrics, picu, trauma,

Rapid Diagnosis of MRSA

Current standard laboratory methods for detection of oxacillin resistance require for isolation, identification, and susceptibility testing at least 48–72 h, although the multiplex PCR assay used is a rapid, sensitive,...

Essentials of Aerosol Therapy in Critically Ill Patients

This book assesses the most appropriate forms of aerosol therapy for critically ill patients. Aerosol therapy is applied for the treatment of several pulmonary diseases in addition to some promising applications intended...