Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients

Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more

Tags: AKI, CKD, coagulation, CRRT, ICU, sepsis, study, therapy,

Opioid Use in Critical Care: A Practical Guide

This book provides a concise yet comprehensive overview on the use of opioids in the ICU, offering practical, real-world recommendations on opioid utilization and alternative therapies. The text explains the physiology and... read more

Tags: analgesia, book, education, ICU, opioids, sedation, therapy,

Thiamine and Ascorbic Acid in Sepsis and Septic Shock

Exploring the individual and synergistic effects of ascorbic acid and thiamine on key pathways implicated in sepsis pathophysiology has not yielded unequivocal evidence supporting their use without concomitant corticosteroids.... read more

Tags: corticosteroids, ICU, infection, sepsis, septic shock, thiamine,

Severe Trauma and Sepsis: Organ Damage and Tissue Repair

This book discusses recent progress in organ damage and tissue repair following severe trauma and sepsis. In part 1, it introduces the theory and clinical practice in organ damage. In part 2, it covers all the subjects of... read more

Tags: book, education, infection, inflammation, sepsis, trauma,

Electrical Impedance Tomography for PEEP Titration in ARDS Patients

ARDS patients may benefit from electrical impedance tomography (EIT)-guided positive end-expiratory pressure (PEEP) titration. The real-time bedside assessment of regional ventilation provided by EIT may result in improved... read more

Tags: ARDS, ICU, mechanical ventilation, PEEP, SOFA, tomography, ventilation, ventilator, VILI,

Intensive Care Fundamentals: Practically Oriented Essential Knowledge for Newcomers to ICUs

This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, is a graphical, dense and concise text describing fundamental theoretical concepts needed for doctors and other professionals new... read more

Tags: book, education, ICU, training,

Impact of Short-Acting Beta-Blockers on the Outcomes of Septic Shock Patients

In patients with septic shock, short-acting beta-blockers may improve survival and reduce new-onset tachyarrhythmias. However, these findings were based on low certainty evidence and given ongoing concerns regarding adverse... read more

Tags: beta-blockers, hypotension, ICU, LOS, mechanical ventilation, sepsis, septic shock, vasopressors,

Pharmacokinetics of Opioid Infusions in the Adult ICU Setting

To counter these pharmacokinetics (PKs) alterations, new therapeutic avenues must be further explored in the ICU to individualize opioid infusions. Embase, MEDLINE, PubMed, CINAHL, and Evidence-Based Medicine Reviews (EBMR)... read more

Tags: ICU, infusion, morphine, opioids, study, therapy, treatment,

Basics of Mechanical Ventilation

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Tags: ARDS, book, education, mechanical ventilation, ventilation,

Predicting SA-AKI Mortality Using XGBoost Algorithm

The integration of advanced techniques with the XGBoost algorithm yielded a highly accurate and interpretable model for predicting Sepsis-Associated Acute Kidney Injury (SA-AKI) mortality across diverse populations. It supports... read more

Tags: AKI, ICU, mortality, prediction, sepsis, study, technology,

Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients

Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more

Tags: AKI, ICU, sepsis, statins, study, therapy, treatment,

Alcohol Consumption Association with the Risk of Bacterial Infection and Pneumonia

Alcohol consumption has a nonlinear J-shaped dose–response association with the risk of acquiring and dying due to bacterial infection and pneumonia, where moderate consumption between one-half and four UK units per day... read more

Tags: ICU, infection, pneumonia, sepsis, study,

Sepsis Management in Resource-limited Settings

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More... read more

Tags: book, infection, resources, sepsis, septic shock,

ARDS Predictors in ICU Patients with Sepsis Using Dynamic Immune Indicator Changes

This study underscores the pivotal role of dynamic immune indicator changes in predicting acute respiratory distress syndrome (ARDS) development among ICU sepsis patients. By incorporating immune cell and immunoglobulin dynamics... read more

Tags: ARDS, ICU, infection, predictors, sepsis, study,

Association Between Aspirin and AKI in Critical Patients with Chest Trauma

This analysis of two datasets reveals that aspirin usage is associated with an increased risk of acute kidney injury (AKI) in critical patients with chest trauma; however, no significant association was observed between the... read more

Tags: AKI, aspirin, ICU, pain, research, trauma,

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation... read more

Tags: book, education, ICU, nursing, resuscitation, therapy, trauma,

Evaluation of Vitamin D Supplementation in Critically Ill Patients

Vitamin D supplementation in critically ill patients may shorten ICU or hospital length of stay, improve SOFA scores, or reduce the duration of mechanical ventilation. Its ability to lower 28-day mortality remains uncertain,... read more

Tags: ICU, LOS, mechanical ventilation, nutrition, research, SOFA, vitamin D,

Factors Influencing the Mortality of Patients with Subarachnoid Hemorrhage in the ICU

Spontaneous subarachnoid hemorrhage (SAH) is a prevalent condition for those between the ages of 50 and 60 years, with a high mortality rate in severe cases. The findings of this study indicate that a history of loss of consciousness... read more

Tags: angiography, hemorrhage, ICU, infection, sepsis, study,

The Triglyceride Glucose Index and Delirium Risk in Sepsis Patients

The triglyceride glucose (TyG) index represents a straightforward and efficacious instrument for nursing staff to ascertain the likelihood of delirium in patients with sepsis during the routine monitoring of their condition.... read more

Tags: delirium, glucose, ICU, monitoring, research, sepsis,

Epidemiology of Myocardial Injury in Trauma Patients

Pathological Troponin concentration elevation occurs in 7% of all trauma patients and it identifies the seriously injured high-risk cohort with worse outcomes than expected based on injury severity. The timing of the maximum... read more

Tags: ECG, echocardiography, ICU, infection, ischemia, LOS, sepsis, study, trauma, troponin,

Management of Severe Traumatic Brain Injury

“Management of Severe Traumatic Brain Injury” is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation... read more

Tags: book, rehabilitation, TBI, trauma, treatment,

Thromboprophylaxis Preferences in the ICU

Low-molecular-weight heparin (LMWH) was the preferred agent for thromboprophylaxis in critically ill patients. There was considerable variation in the application of LMWH for prophylaxis, reflected by the use of different... read more

Tags: heparin, ICU, thromboembolism, VTE,

You Can Stop Humming Now: A Doctor’s Stories of Life, Death, and in Between

Modern medicine is a world that glimmers with new technology and cutting-edge research. To the public eye, medical stories often begin with sirens and flashing lights and culminate in survival or death. But these are only...

Neurocritical Care for the Advanced Practice Clinician

By utilizing a review of case-based studies and providing concise management recommendations from leaders in the field, this book provides essential knowledge for those practicing in a dynamic specialty. In the rapidly developing...