Septic Shock Metabolic Subgroups and Clinical Outcome

Three metabolic clusters exist in patients with septic shock with most metabolites differing between clusters and lipid species being most influential. Cluster proportions evolved over time with a high metabolite group becoming... read more

Tags: cytokine, ICU, infection, phenotypes, sepsis, septic shock, SOFA, study, treatment, vasopressin,

Blood Pressure Disorders in Acute and Chronic Kidney Diseases (Updates in Hypertension and Cardiovascular Protection)

This new book is intended to be an in-depth and up-to-date guide to the various aspects of the association between blood pressure disorders and acute/chronic renal diseases. In addition, this work includes discussion of topics... read more

Tags: AKI, book, education, hypertension, ICU, nephrology,

VAP Recurrences Definition: European Experts Consensus

This consensus by European experts proposes four different ventilator-associated pneumonia (VAP) recurrence entities which should facilitate the harmonization of recurrence criteria for clinical practice and future studies.... read more

Tags: antibiotics, diagnosis, ICU, infection, VAP, ventilation,

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

This new book will serve as a useful resource for all pharmacists involved in the management of critically ill patients, whatever their level of experience and training. There are few textbooks aimed specifically at critical... read more

Tags: book, diagnostics, ECMO, ICU, mechanical ventilation, nutrition, pharmacists, pharmacology, pulmonary embolism, therapy,

Rapid Clinical Effects of Convalescent Plasma Therapy in Severe COVID-19 ARDS

Administration of convalescent plasma (CP) in critically ill COVID-19 patients leads to a rapid and highly significant improvement of sequential organ failure assessment (SOFA) score along with improvements in respiratory... read more

Tags: ARDS, COVID-19, hemodynamics, mechanical ventilation, SOFA, study,

Sepsis: Staging and Potential Future Therapies

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Variability in pathogenesis and complex pathophysiology often delay diagnosis and create significant challenges for clinical... read more

Tags: book, diagnosis, infection, research, sepsis, septic shock, therapy, treatment,

Management of ARDS COVID-19 Patients Using Hemoperfusion and CRRT

Combined hemoperfusion (HP) and continuous renal replacement therapy (CRRT) hold promise as a potential intervention for severe COVID-19 cases with multiple organ dysfunction, leading to improved clinical outcomes. Fifty-six... read more

Tags: AKI, ARDS, COVID-19, CRRT, diagnosis, hemodynamics, ICU, study, therapy,

VA-ECMO and Pulmonary Reperfusion

The study by Stadlbauer and colleagues provides further evidence that veno-arterial extracorporeal membrane oxygenation (VA-ECMO) should—whenever necessary—be used, as a bridge to pulmonary reperfusion, but not as a bridge... read more

Tags: ECMO, ICU, oxygenation, pulmonary embolism, study, treatment,

Mechanical Ventilation in Patient with Respiratory Failure

This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more

Tags: book, education, ICU, mechanical ventilation, pulmonology,

Fluid Management Impact on Outcomes in Sequential Extracorporeal Support

Sepsis is a life-threatening condition characterized by dysregulated inflammatory responses, often leading to multiple organ dysfunction and high mortality rates. Continuous renal replacement therapy (CRRT) and extracorporeal... read more

Tags: CRRT, ECMO, ICU, inflammation, sepsis, septic shock, study,

Mortality in Patients with SA-AKI Using the MIMIC-III Database

In this study, we identified critical factors influencing mortality in patients with Sepsis-Induced Acute Kidney Injury (SA-AKI) using the MIMIC-III database. The primary findings of our research, including advanced age,... read more

Tags: AKI, albumin, antibiotics, bilirubin, mortality, research, resuscitation, sepsis,

Leptin and Linterlukin-6 Relationship and Influence of Mortality in Sepsis

High leptin levels might counteract the adverse prognostic effect of elevated IL-6 on septic mortality. At the same IL-6 level, leptin could predict septic mortality. Leptin might be a protecting factor for men and gender-different... read more

Tags: cytokine, ICU, inflammation, sepsis, septic shock, study,

Infection Microbiology and Management

Infection: Microbiology and Management provides a core resource for the understanding of medical microbiology and infectious diseases. Content covers microbiological and clinical diagnosis, through to clinical management,... read more

Tags: book, education, epidemiology, infection,

TyG Index And Short-term Mortality in Patients with Cardiogenic Shock

The triglyceride-glucose (TyG) index is significantly associated with short-term mortality in patients with cardiogenic shock (CS) and may serve as a useful biomarker for risk stratification. This retrospective cohort study... read more

Tags: cardiogenic shock, CKD, creatinine, CRRT, ICU, mortality, pneumonia, sepsis, SOFA, study,

Severe Adenoviral Infections: Disease Progression and Poor Prognostic Markers

Low hemoglobin, high serum ferritin, and high LDH in the second week are markers of disease progression and poor prognostic markers in severe adenoviral infections, emphasizing further research and targeted interventions.... read more

Tags: biomarkers, CRP, ICU, infection, mechanical ventilation, MODS, pneumonia, prognosis, research, study, ventilation,

Promising Prognostic Predictors in Sepsis Patients Using Lactate and Albumin Ratio

Serum Lactate/Albumin ratio and BAR ratio were significantly higher in sepsis and/or septic shock and associated with increased length of hospital stay and increased in-hospital mortality and poor clinical outcome inside... read more

Tags: albumin, hypertension, ICU, lactate, mechanical ventilation, mortality, pneumonia, prognosis, sepsis, septic shock, SOFA, study,

ECMO in the Adult Patient (Core Critical Care)

Extracorporeal membrane oxygenation (ECMO) is developing rapidly, and is now part of the toolkit for the management of all patients with severe respiratory or cardiac failure. Clinicians of all disciplines are in need of... read more

Tags: book, ECMO, oxygenation, technology, tools,

Glycemic Control Role in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19

This study demonstrates that among hospitalized COVID-19 patients with type 2 diabetes mellitus, poor glycemic control (HbA1c ≥ 7%) correlates with increased systemic inflammation, greater disease severity, and worse clinical... read more

Tags: COVID-19, CRP, diabetes, hypoglycemia, ICU, inflammation, mechanical ventilation, study,

Continuous Glucose Monitoring-Based Insulin Titration Protocol for Type 2 Diabetes Patients

The continuous glucose monitoring (CGM)-based insulin titration protocol by Olsen et al has been successfully implemented for titrating basal, prandial, and correctional insulin in inpatients with type 2 diabetes in non-ICU... read more

Tags: diabetes, ICU, insulin, monitoring, neurology, study,

Increased Sodium Levels Associated with Ceftriaxone Administration

Serum sodium elevation is considered a frequent manifestation in critically ill patients, with significant clinical outcomes and requiring timely management. This case report suggests a possible association between the use... read more

Tags: antimicrobial, diagnosis, hemodynamics, hypernatremia, ICU, mechanical ventilation, pneumonia, prognosis,

Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple

A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex, acid-base, fluid, and electrolyte problems. Useful to medical students, interns and residents, nurses... read more

Tags: book, education, electrolytes, nephrology, therapy,

Dynamic Left Ventricular Outflow Tract Obstruction Induced by IABP in Patient with Angioedema

Mechanical circulatory support with intra-aortic balloon pump (IABP) can aid in the treatment of cardiogenic shock but may rapidly become detrimental due to the reduction in systolic arterial afterload in patients with predispositions... read more

Tags: angioedema, diagnosis, echocardiography, ICU, mechanical ventilation, treatment,

Neonatal and Pediatric Respiratory Care

A comprehensive text on respiratory care for neonates, infants, and children, Neonatal and Pediatric Respiratory Care, 4th Edition provides a solid foundation in the assessment and treatment of respiratory care disorders....

The Gene: An Intimate History

A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are. From the Pulitzer Prize-winning author of The Emperor of All Maladies, a fascinating history of the gene...