Anticoagulation Reversal Strategies for Warfarin Associated Acute Gastrointestinal Bleeding

Patients who received prothrombin complex concentrate (PCC) had a threefold increase in mortality compared to fresh frozen plasma (FFP), vitamin K alone, or no reversal, even after adjusting for severity of the bleeding.... read more

Tags: bleeding, endoscopy, hemodynamics, ICU, study, thromboembolism, thrombosis, warfarin,

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more

Tags: book, ICU, intubation, mechanical ventilation, sepsis, trauma, ventilation,

Hemodynamic Stabilization Using CRRT and cIVNa Combination Therapy

Compared with conventional continuous renal replacement therapy (CRRT), combination therapy of CRRT and continuous intravenous sodium infusion therapy (cIVNa) increased blood pressure, enhanced urinary volume, and reduced... read more

Tags: AKI, CRRT, dialysis, hemodynamics, hypotension, ICU, RRT, study, therapy, treatment, vasopressors,

Hemodynamic Monitoring in the ICU

This book describes the pathophysiological significance of the hemodynamic monitoring parameters available to the clinician and their role in providing reliable and reproducible information on the cardiocirculatory status... read more

Tags: book, education, hemodynamics, ICU, monitoring,

Endotracheal Tube Cuff Pressure Monitoring and VAP Occurrence

This study demonstrated that maintaining endotracheal tube cuff pressure at 30 cm H2O through monitoring every 8 h did not result in a greater incidence of under-inflation (pressures... read more

Tags: ARDS, ICU, mechanical ventilation, monitoring, pneumonia, pulmonary edema, study, VAP, ventilation,

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their... read more

Tags: biomarkers, book, research, sepsis, trauma, treatment,

Early Acetaminophen Administration Associated with Lower Mortality Among ARDS Patients After Coronary Artery Bypass Grafting

The use of acetaminophen (APAP) at 48h after coronary artery bypass grafting (CABG)-acute respiratory distress syndrome (CABG-ARDS) was associated with lower early postoperative mortality, while shortening the length of hospital... read more

Tags: acetaminophen, ARDS, CABG, ICU, mechanical ventilation, study,

Thirst Management in Orotracheally Intubated and Mechanically Ventilated Patients

Symptom Management Theory (SMT)-based thirst management is an effective strategy. The 5 mL cold water spray method significantly reduces thirst intensity and distress in mechanically ventilated patients under fasting and... read more

Tags: delirium, ICU, intubation, mechanical ventilation, recovery, research, sleep, study, ventilation,

Red Book: Report of the Committee on Infectious Diseases

Extending an 8-decade tradition of excellence, Red Book® provides the most reliable and clinically useful information on the manifestations, etiology, epidemiology, diagnosis and treatment of more than 200 childhood infectious... read more

Tags: book, diagnosis, epidemiology, infection, treatment,

Inadequate Empirical Antibiotic Therapy in VAP: Risk Factors and Outcomes

Ventilator-associated pneumonia (VAP) caused by MDR pathogens were highly likely to receive inadequate empirical antibiotic therapy. The mortality rate and intubation duration were significantly longer in inadequately treated... read more

Tags: antibiotics, ICU, infection, mechanical ventilation, study, therapy, VAP, ventilation,

A Novel Mechanism for COVID-19 Related Thrombotic Events: Platelet NO/ROS Equilibrium

The finding that platelet NO/ROS production imbalance contributes to the elevated risk of thrombotic events in COVID-19 has important clinical implications. Restoration of platelet NO production, as well as attenuation of... read more

Tags: COVID-19, ICU, infarction, infection, stroke, study, thromboembolism, thrombosis, treatment,

Association Between Initial Blood Product Transfusion with a Higher Plasma-to-red Blood Cell Ratio and Mortality in Adults with Severe Bleeding Following Trauma

This study demonstrates that a high fresh-frozen plasma (FFP) to packed red blood cells (PRBC) ratio (>1:1.5) is associated with reduced 24-hour and 30-day mortality rates among trauma patients with massive hemorrhage. However,... read more

Tags: ICU, mortality, transfusion, trauma, ventilation,

Lung Ultrasound in the Critically Ill: The BLUE Protocol

Written by a pioneer in critical care ultrasound, this book discusses the basic technique and “signatures” of lung ultrasound and explains its main clinical applications. The tools and clinical uses of the BLUE... read more

Tags: ARDS, ARF, book, education, ultrasound,

Causes of Death in Patients Undergoing ECPR

Refractory shock was the leading cause of death among our cohort of extracorporeal cardiopulmonary resuscitation (ECPR) patients, followed closely by neurological complications, while other causes are rare. In this post-hoc... read more

Tags: ECPR, ICU, OHCA, oxygenation, resuscitation, study,

Rib-Indexed POCUS vs. Chest X-Ray for Lung Recruitment Assessment in Ventilated Neonates with Moderate-Severe ARDS on Pulmonary Surfactant Therapy

Rib-indexed posterior approach POCUS is a reliable, radiation-free modality for real-time lung recruitment assessment in neonates with NARDS, demonstrating noninferiority to CXR. Notably, our study is the first to propose... read more

Tags: ARDS, ECMO, mechanical ventilation, neonates, oxygenation, pediatrics, POCUS, ultrasound, ventilation,

COVID-19 Handbook: Navigating the Future of Healthcare

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

Tags: ARDS, book, coronavirus, COVID-19, infection, pandemics, treatment,

Mechanical Power Impact Normalized to Predicted Body Weight on Outcomes in Pediatric ARDS

Higher mechanical power (MP) was associated with fewer ventilator (VFD) and ICU free days (IFD). The causal effect of MP on VFD and IFD was fully mediated by the impairment in oxygenation. This is a post-hoc analysis of data... read more

Tags: ICU, mechanical ventilation, oxygenation, pediatrics, study, ventilator,

Practical Perioperative Transesophageal Echocardiography

A practical, full-color guide with videos, Practical Perioperative Transesophageal Echocardiography, 2nd Edition, by Drs. David Sidebotham, Alan F. Merry, Malcolm E. Leggett, and Mark L. Edwards, will help improve your diagnosis...

Hot Lights, Cold Steel: Life, Death and Sleepless Nights in a Surgeon’s First Years

This story of Collins’ four-year surgical residency traces his rise from an eager but clueless first-year resident to accomplished Chief Resident in his final year. With unparalleled humor, he recounts the disparity...