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Issue #321 - View in the Browser

CRITICAL CARE NEWS

Sponsored By ChronicCareIQ

ChronicCareIQ

Predicting the Next 48 Hours: Machine Learning Delivers Dynamic, Interpretable ICU Mortality Forecasts

The LGBM-48h algorithm provides a dynamic, clinically applicable, and interpretable framework for 48-hour ICU mortality risk prediction. By establishing mortality risk-based categories and showing how key features change... read more

Tags: AI, ICU, mortality, prediction, research, technology,


Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide

This book provides a comprehensive overview on sedation and analgesia for the pediatric intensivist. Divided into two primary sections, the text presents a framework on how to care for patients who need sedation, analgesia,... read more

Tags: analgesia, book, education, ICU, pediatrics, PICU, sedation,

Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide


A Shift in Strategy: Rethinking Blood Transfusions for Brain Injury

Recent clinical trials have challenged the standard practice of using a restrictive Red Blood Cell (RBC) transfusion strategy for critically ill brain-injured patients (ABI). Restrictive Approach is Questioned: The prevailing... read more

Tags: ABI, anemia, brain injury, hypoxia, ICU, monitoring, oxygenation, strategy, TBI, transfusion,


Sepsis Danger: High Ferritin Levels Flag Risk of Acute Liver Injury

This study used data from the MIMIC-IV database (training group) and an external hospital dataset (clinical validation group) to develop and validate a prediction model for sepsis-associated acute liver injury (SALI). The... read more

Tags: ALI, CRRT, diagnosis, ICU, inflammation, nephrology, prediction, sepsis, study, treatment,


Melatonin for Delirium Prevention: The Sleep Hormone Doesn’t Pass the ICU Test

Despite its frequent occurrence and association with increased mortality in critically ill patients, delirium prevention remains challenging. A recent meta-analysis sought to resolve conflicting results from randomized controlled... read more

Tags: delirium, ICU, mechanical ventilation, melatonin, mortality, sedation, study,


VAEs are Real: Advanced Modeling Confirms Ventilator Events Drive Worse Outcomes

The study by Nakahashi et al. significantly advances our understanding of Ventilator-Associated Events (VAEs) by using advanced causal modeling. Their findings firmly establish that VAEs are clinically significant events... read more

Tags: COVID-19, ICU, infection, mechanical ventilation, pneumonia, sedation, SOFA, study, VAE, VAP, vasopressors, ventilator,


Delirium vs. Encephalopathy: Unifying the Approach to Brain Dysfunction

Current clinical practice and research are limited by the separate, or dichotomized, use of the terms “encephalopathy” and “delirium.” This separation hinders a unified approach to understanding acute... read more

Tags: delirium, EEG, encephalopathy, guidelines, hypoxia, ICU, morbidity, mortality, sedation, septic shock, study,


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ICU Protocols: A Step-wise Approach, Vol II

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more

Tags: book, education, ICU, obstetrics, trauma, treatment,

ICU Protocols: A Step-wise Approach, Vol II

Low Phosphate Linked to Extended Hospitalization in Neonatal Sepsis

This retrospective cohort study investigated the relationship between serum phosphate levels and outcomes in neonates with sepsis using data from the Pediatric Intensive Care (PIC) database. Lower serum phosphate levels are... read more

Tags: AKI, ALI, biomarkers, diagnosis, hypophosphatemia, ICU, neonates, PICU, sepsis, study,


ICU Risk Check: Simple Blood Biomarker Predicts Mortality in Heart Attack Patients

A study using data from the MIMIC-IV database investigated the prognostic value of the Neutrophil-Platelet Activity Ratio (NPAR) in critically ill adult patients admitted to the ICU with a first acute myocardial infarction... read more

Tags: AMI, COPD, ICU, inflammation, myocardial infarction, SOFA, study,


Remimazolam Triumphs Over Propofol for Safer ICU Sedation During Bronchoscopy

This randomized controlled trial compared remimazolam to propofol for moderate sedation during fiberoptic bronchoscopy (FB) in critically ill patients in the Surgical Intensive Care Unit (SICU) who had pre-existing liver... read more

Tags: anesthesia, bronchoscopy, hemodynamics, hypotension, ICU, propofol, sedation, study,



Sepsis Management in Resource-limited Settings

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More... read more

Tags: book, infection, resources, sepsis, septic shock,

Sepsis Management in Resource-limited Settings

Lung Ultrasound Speeds Up VAP Diagnosis and Improves ICU Outcomes

This prospective randomized controlled study investigated whether using Lung Ultrasound (LUS) as a primary bedside tool for diagnosing Ventilator-Associated Pneumonia (VAP) could outperform the standard radiological approach... read more

Tags: antibiotics, diagnosis, ICU, mechanical ventilation, monitoring, pneumonia, SOFA, ultrasound, VAP,


The REGULATE Trial: Finding the Best Blood Pressure Drug for Severe Brain Injury

The REGULATE trial is a crucial, large-scale, randomized study designed to determine the optimal vasopressor (blood pressure medication) strategy for patients with severe traumatic brain injury (TBI). The goal is to see how... read more

Tags: brain injury, norepinephrine, study, TBI, trial, vasopressin,


Machine Learning Can Effectively Identify Septic Patients with AKI

Causal Machine Learning (ML) framework outperformed random forest model in identifying patients with AKI and sepsis who benefit from restrictive fluid therapy. This provides a data-driven approach for personalized fluid management... read more

Tags: AI, AKI, fluid therapy, research, sepsis, septic shock, study, technology,


Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

The new edition presents updates regarding new clinical applications of noninvasive mechanical ventilation and discusses recent technical advances in this field. The opening sections are devoted to theory, equipment, with... read more

Tags: book, education, mechanical ventilation, research, ventilator,

Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

Most ICU Infections Miss the Mark for Classic Fever

The large number of patients being treated for infection without a high fever suggests that many could be ideal candidates for a clinical trial investigating induced hyperthermia (purposely raising body temperature) as a... read more

Tags: antibiotics, antimicrobial, fever, hyperthermia, ICU, infection, mechanical ventilation, sepsis, study,


More Than Just Acid: Navigating the Complexities of Lactate in Critical Care

Lactate is a vital marker in critical care, but its meaning is complex, reflecting an interplay of perfusion, metabolism, organ function, and stress. Clinicians must adopt a nuanced, multimodal approach to interpretation,... read more

Tags: CRT, diagnostics, hemodynamics, hyperlactatemia, hypoxia, ICU, lactate, oxygenation, perfusion, prognostics, RRT,


JOKES/MEMES

Get a much-needed dose of laughter with our new joke/meme section tailored for critical care professionals. Do you have a joke or meme about critical care medicine you'd like to share? Send us your best one!

IV Pump Beep

Two ICU doctors and a nurse are having lunch, comparing notes on their jobs.
The first doctor says, “I hate coming in on my day off.” The second doctor says, “I hate when my pager goes off during dinner.”
The ICU nurse just sighs and says, “I hate it when I’m walking to my car after a 12-hour shift and I can still hear the phantom beeping of the IV pump that I forgot to silence.”

See More Critical Care Jokes and Memes

NEW MEDICAL DEVICES

Discover new cutting-edge medical devices and systems that are revolutionizing patient care and improving outcomes in the ICU. Did your ICU recently adopt a new medical device? We want to hear about it!

ChronicCareIQ

ChronicCareIQ, a Connected Care platform designed to help medical practices implement and manage Chronic Care Management (CCM) and Remote Patient Monitoring (RPM) programs. The system enhances care quality while simultaneously increasing practice revenue.

Top Benefits of ChronicCareIQ

Improved Visibility (Real-Time Data & Focus):

  • The platform provides complete, real-time data on patient status.
  • Staff receive automatic notifications when patient trends exceed set clinical thresholds, allowing them to prioritize care for the highest-need patients.
  • In-depth monthly trend reports offer both clinical and financial insights into the programs’ success.

Improved Patient Outcomes (Proactive Management):

  • The platform keeps the care team continuously informed of patient status in between office visits.
  • Access to real-time data allows staff to proactively manage patients’ chronic and complex conditions, leading to better patient outcomes.

Increased Staff Productivity (Automation & Efficiency):

  • Proactive patient engagement reduces inbound phone calls and follow-up time.
  • The system automatically captures and documents care coordination activities (phone calls, EHR time) required for reimbursement.
  • This automation allows practices to support more patients without increasing staff size.

Better Reimbursements (Simplified Billing):

  • The platform helps practices get reimbursed for care management work they are already doing.
  • It automatically prepares all necessary billing documentation each month, simplifying the process and allowing staff to focus on patients.
  • The system helps capture rising CMS reimbursement rates for preventative care services.

Learn More

See More New Medical Devices

LATEST CRITICAL CARE PODCASTS

Every week we scour the web to bring you the latest podcast episodes related to ICU and Critical Care Medicine. Here are the latest podcasts:

Critical Issues in ED Intubation
Emergency physicians intubate critically ill patients daily. Unfortunately, up to 17% of ED intubations can be complicated by peri-intubation hypoxemia, hypotension, and cardiac arrest. Listen to podcast

Building a POCUS Powerhouse: Point-of-Care Ultrasound Workflow, Training and Innovation in Pulmonary Critical Care
How Cleveland Clinic transformed a single ultrasound machine into a cutting-edge, hospital-wide POCUS program. Listen to podcast

Anteroposterior and Lateral Epiglottis-Related Obstruction in Adult Obstructive Sleep Apnea
Interview with Eric J. Kezirian, MD, MPH author of Anteroposterior and Lateral Epiglottis-Related Obstruction in Adult Obstructive Sleep Apnea. Hosted by Paul C. Bryson, MD MBA. Listen to podcast

See More Podcasts

CRITICAL CARE UPCOMING EVENTS

LIVES 2025
Oct. 25, 2025 - Munich, Germany

In 2025, we invite you once again to join for 5 eventful days, between 25 and 29 October, for pre-congress educational courses, scientific sessions and educational workshops.


2025 Tri-Society Cardiac & Thoracic Symposium
Nov. 19, 2025 - Sydney, Australia

2025 Tri-Society Cardiac & Thoracic Symposium (3SCTS) which is a combined scientific meeting of three Australasian cardiothoracic societies: anaesthesia (ANZCA), surgery (ANZCTS), and perfusion (ANZCP).


Oslo HEMS Conference
Dec. 01, 2025 - Oslo, Norway

Following the success of Oslo HEMS Conference 2023 we are busy at work on the program for the 2025 conference. We will bring together the finest minds in Helicopter Emergency Medical Services as we delve into presentations, cutting-edge techniques and life-saving innovations whilst creating a host of unforgettable networking opportunities.


See More Events

NEW CRITICAL CARE JOBS

Critical Care Intensivist
Cleveland, Ohio
The Department of Anesthesiology at the Cleveland Clinic is recruiting qualified intensivists with career interests in critical care medicine.

CVICU Intensivist
Abington, Pennsylvania
Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value.

Physician Critical Care Medicine
Danville, PA
Diagnoses, treats and supports patients with multiple organ dysfunction. May facilitate and coordinate patient care among the primary physician, the critical care staff and other specialists. Position works on a shift-based schedule and does not accrue PTO or CME days.

See More Jobs

FEATURED CRITICAL CARE BOOKS

Immunotherapy

The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types...

Read More
Immunotherapy

Textbook of Ventilation, Fluids, Electrolytes and Blood Gases

The Textbook of Ventilation, Fluids, Electrolytes and Blood Gases encompass essential topics for which thorough education and training is a must for any clinician who manages these patients. This book has four sections, each...

Read More
Textbook of Ventilation, Fluids, Electrolytes and Blood Gases

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