In-line Filtration of Intravenous Infusion May Reduce Organ Dysfunction of Adult Critical Patients

ccforum.biomedcentral.com November 25, 2019

In-line filtration with finer 0.2 and 1.2 μm filters may be associated with less organ dysfunction and less inflammation in critically ill adult patients.

Comparing fine filter vs control filter cohort, respiratory dysfunction, pneumonia, sepsis, interleukin-6, and length of ICU days and hospital stay were reduced.

This single-centre, retrospective controlled cohort study assessed the effect of in-line filtration of intravenous fluids with finer 0.2 or 1.2 μm vs 5.0 μm filters in critically ill adult patients.

From a total of n = 3215 adult patients, n = 3012 patients were selected by propensity score matching and assigned to either a fine filter cohort or a control filter cohort.