5 Year Impact of ICU-acquired Neuromuscular Complications

link.springer.com June 13, 2020

ICU-acquired neuromuscular complications may impact 5-year morbidity and mortality. MRC sum score, even if slightly reduced, may affect long-term mortality, strength, functional capacity and physical function, whereas abnormal CMAP only related to long-term mortality.

Sub-analyses of a prospective, 5-year follow-up study including 883 EPaNIC patients systematically screened in ICU for neuromuscular complications with MRC sum score, electrophysiology on day 8 ± 1 to quantify compound muscle action potential, or both.

Both lower MRC sum score at ICU discharge, indicating less strength, and abnormal CMAP, indicating nerve/muscle dysfunction, independently associated with increased 5-year mortality.