Use of ECMO in Acutely Poisoned Pediatric Patients in US

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Extracorporeal Membrane Oxygenation (ECMO) may improve the hemodynamic and metabolic status of poisoned pediatric patients. Persistent hypotension, acidemia/acidosis, and elevated Pao2 after 24 hours of ECMO were associated with mortality.

During our study period, 86 cases of acute poisoning were identified and included in the analysis.

The median age was 12.0 year and 52.9% were female.

The most commonly reported substance exposures were hydrocarbon (n = 17; 19.8%), followed by chemical asphyxiants (n = 14; 16.3%), neuroactive agents (n = 14; 16.3%), opioid/analgesics (n = 13; 15.1%), and cardiovascular agents (n = 12; 14.0%).

Single substance exposures were reported in 83.7% of the cases.

The intention of the exposure was unknown in 65.1%, self-harm in 20.9% and 10.5% was unintentional exposure.

Fifty-six patients (65.1%) survived.

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