Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection
dovepress.comThe results of this study indicate that surgical intervention has a significant effect on improving patients’ hemodynamic parameters, with postoperative MAAD and LVEDd reduced compared to preoperative levels, while LVEF increased compared to preoperative levels, indicating that surgery plays an important role in restoring cardiac function.
Additionally, the incidence of postoperative delirium in this study was 35.25%. Multivariate Logistic analysis revealed that age ≥60 years, hypertension, history of stroke, surgery duration >6 hours, cardiopulmonary bypass time >3 hours, and deep hypothermic circulatory arrest time >40 minutes were independent risk factors influencing the occurrence of postoperative delirium in patients with Stanford Type A aortic dissection.
These findings provide important evidence for clinicians to identify high-risk patients preoperatively and implement individualized preventive measures, thereby improving postoperative prognosis and long-term quality of life.
It is important to note that, despite revealing some important clinical associations and risk factors, this study still has certain limitations, primarily including the following points:
Limited sample size: This study only included 139 patients, with a relatively small sample size, which may limit the generalizability and external validity of the study results.
Single-center study: This study was a single-center retrospective analysis, and the characteristics of the patient population and surgical procedures may be influenced by the specific hospital conditions, potentially making it difficult to fully reflect the situation in other medical institutions.
This study’s retrospective nature relies on the availability and accuracy of medical records, which may contain instances of missing or incomplete data.