Our study suggests that treating older adults with therapies recommended by the Surviving Sepsis Campaign may improve outcomes in this age group, although mortality remains high for older adults with sepsis.

In addition, given our reported descriptive results, we can hypothesize that admission to an ICU with sepsis may be associated with a decline in functional status.

This may be important for both physicians and families to consider when discussing health goals and site of care after discharge.

Although studies evaluating the impact of each intervention (eg, class of antimicrobial, dosage, and timing) in improving mortality and functional status post-ICU admission in older adults with sepsis are needed, further studies that address patient treatment goals earlier in the trajectory of ICU care are also warranted.

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