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Levosimendan in high-risk patients undergoing cardiac surgery

ccforum.biomedcentral.com October 22, 2017

levosimendan-in-high-risk-patients-undergoing-cardiac-surgery

Levosimendan reduces mortality in patients with preoperative severely reduced LVEF but does not affect overall mortality. Levosimendan reduces the need for RRT after high-risk cardiac surgery. Six RCTs were included in the meta-analysis, five of which investigated only patients with LVEF ≤ 35% and one of which included predominantly patients with LCOS.

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