n the ALBIOS trial, persistence of low (<70%) central venous oxygen saturation (ScvO2) during early sepsis was associated with higher 90-day mortality, possibly because it reflected underlying cardiac dysfunction, according to an analysis published online in the journal CHEST. Subjects with ScvO2 <70% may benefit most from individually tailored interventions aimed at normalising the balance between systemic oxygen delivery and consumption, researchers say. Central venous oxygen desaturation (ScvO2 <70%) signals a mismatch between oxygen delivery and consumption in the upper, and possibly even in the lower, part of the human body.

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