Prior Exposure to ACEi Increased Cardiovascular Response to Angiotensin-II

Prior Exposure to ACEi Increased Cardiovascular Response to Angiotensin-II

Prior exposure to RAS-inhibiting medications was associated with an altered RAS profile and cardiovascular response to angiotensin-II treatment in patients with catecholamine-refractory vasodilatory shock. ACE-inhibitor... read more

Remimazolam Effect on Hemodynamics in Patients with Septic Shock

Remimazolam Effect on Hemodynamics in Patients with Septic Shock

Remimazolam is safe and effective for inducing general anesthesia in patients with septic shock. Low, medium, and high doses of remimazolam can maintain a stable hemodynamic state, and the recovery of hepatic and renal function... read more

Fluid Boluses May Improve CRT

Fluid Boluses May Improve CRT

Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to further explore... read more

Vasopressor Reduction Effect of Polymyxin B Hemoperfusion

Vasopressor Reduction Effect of Polymyxin B Hemoperfusion

This study aimed to evaluate the effect of polymyxin B hemoperfusion (PMX-HP) in patients with peritonitis-induced septic shock who still required high dose vasopressors after surgical source control. A total of 338 patients... read more