Among patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did not result in statistically significantly more days alive without life support at 28 days than dexamethasone 6 mg. However, the confidence interval... read more

This book uses real-world clinical case analyses of hot topics to provide insights into noninvasive mechanical ventilation (NIV). Written by leading international teachers and experts, it features a selection of “major... read more

Avoidance of nitrous oxide and the concomitant increase in inspired oxygen concentration decreases the incidence of complications after major surgery, but does not significantly affect the duration of hospital stay. The routine... read more

The hemodynamic evaluation of patients with acute circulatory failure and respiratory failure has in the past usually been performed using invasive procedures but in recent years less invasive monitoring devices have been... read more

Mortality after ECMO for patients with COVID-19 worsened during 2020. These findings inform the role of extracorporeal membrane oxygenation (ECMO) in COVID-19 for patients, clinicians, and policy makers. In 2020, 4,812 patients... read more

Waveform capnography is emerging as a standard monitoring tool to improve safety among intubated patients. Failure to use waveform capnography contributed to >70% of ICU-related airway deaths in the NAP4 audit. Capnography... read more

COVID-19-related ARDS has no consistent respiratory subphenotype. Patients diverged from a fairly homogenous to a more heterogeneous population, with trajectories of ventilatory ratio and mechanical power being the most discriminatory.... read more

This book describes current, evidence-based guidelines for damage control interventions across the field of trauma care with the aim of enabling clinicians to apply them to best effect in daily clinical practice. Emphasis... read more

Our systematic review failed to find high-quality evidence to suggest that ambulation alone is an appropriate or effective prophylaxis for venous thromboembolism. Although some studies suggest that ambulation may reduce venous... read more

In July, 2021, another wave of COVID-19 began in the USA as the highly infectious delta (B.1.617.2) SARS-CoV-2 variant drove outbreaks predominantly affecting states with relatively low vaccination coverage. Some US states... read more

The ventilator significantly overestimates the RSBI value compared to the standard technique by Wright spirometer. The average RSBI vent value among 5 time points (0, 15, 30, 45, and 60 s) was found to best correlate with... read more

A novel area of compression over the left sternal border at the inter-nipple line would result in compressions over the LV in nearly three-quarters of our study participants. Future research should investigate whether this... read more

In this systematic review, we evaluated the temporal progression of clinical abnormalities experienced by patients who recovered from an infection with SARS-CoV-2, starting with a mean of 30 days post–acute illness and... read more

Hypocalcemia is a common complication of phototherapy. Serum calcium levels should be monitored in all the full-term neonates receiving phototherapy. Hyperbilirubinemia was present in 23.3% of neonates admitted to the neonatal... read more

Many parts of the ED encounter interfere with patient or family comprehension, not the least of which is the ED’s noisy, hurried environment. But other factors affect what they understand and remember about the encounter—their... read more

Brain injury is frequent in extracorporeal membrane oxygenation patients, although the majority of survivors have favorable neurocognitive outcomes. More research is needed in order to understand the etiology of such injuries.... read more

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

Toxicology histories are notoriously unreliable. Any available medical records, especially medication lists. Timing & amount of ingestions. Immediate vs. sustained-release formulations. Consider inquiring specifically... read more