The Easiest Way to Reduce Antibiotic Resistance Might be Shorter Duration

Antibiotic stewardship garners a lot of attention these days, but we face unique challenges to execute guidelines successfully given that we write more than 13 million antibiotic prescriptions every year in EDs. Variations... read more

Tags: antibiotics, CAP, guidelines, sepsis, study, treatment, trial,

The Washington Manual of Critical Care 4th Edition

Part of the popular Washington Manual® handbook series, The Washington Manual of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef,... read more

Tags: asthma, book, myocardial infarction, sepsis, shock,

Lower or Higher Oxygenation Targets in the ICU

This study reported no overall differences comparing a PaO2 target of 8–12 kPa on mortality or days alive without life support in 90 days. Subgroup analyses suggested heterogeneity of treatment effects (HTE) in patients... read more

Tags: COVID-19, ICU, oxygenation, study, treatment,

EKG/ECG Interpretation Made Easy

In this guide, you will understand how ECGs are performed, what they represent about the heart, and what it means to see something you don’t think is normal. Before you get into the hard stuff—the actual interpretation... read more

Tags: book, ECG, education, EKG, infarction, ischemia,

Complex Infusion Volumes Interaction and Confounding Factors with Lactate Clearance in Septic Shock

A recent article by Ahlstedt et al. published in Intensive Care Medicine examining the impact of restrictive fluid management on lactate clearance in septic shock patients within the intensive care unit (ICU) piqued our interest.... read more

Tags: ICU, lactate, sepsis, septic shock, study, vasopressors,

The Hidden Value of MRI: Modifying Treatment Decisions in C-spine Injuries

This study provides a critical evaluation of the implications of additional magnetic resonance imaging (MRI) use in the diagnosis of c-spine injuries. We have demonstrated that an adjunctive MRI extends patients’ ED... read more

Tags: diagnosis, ICU, LOS, MRI, study, tomography, trauma,

Navigating the Complexity of ECMO and Positioning in ARDS Treatment

We read with great interest the network meta-analysis by Sud et al. comparing venovenous extracorporeal membrane oxygenation (VV-ECMO), prone positioning, and supine mechanical ventilation in patients with severe hypoxemic... read more

Tags: ARDS, ECMO, hypoxemia, mechanical ventilation, study,

Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals

Empiric treatment for suspected community-onset sepsis accounts for about half of broad-spectrum antibiotic use in US hospitals even though resistant organisms are isolated in only 7% of patients with community-onset sepsis... read more

Tags: antibiotics, bacteremia, infection, pneumonia, sepsis, treatment,

Quick Reference to Critical Care

Sharpen your critical care skills, with the fully updated Quick Reference to Critical Care, fifth 5th edition. This well-illustrated pocket guide covers the full range of critical care scenarios, listing each disorder, medication,... read more

Tags: book, education, nursing, reference,

AI to Predicting Mortality Risk in ICU Patients with AKI

To address the limitations of early acute kidney injury (AKI) prediction, researchers have increasingly turned to machine learning methods. However, the success of these models hinges on the selection of relevant features.... read more

Tags: AKI, ICU, research, study, technology,

Tailoring Antithrombotic Treatment in Patients with Acute Myocardial Infarction and Cancer

For more than two decades, dual platelet antiplatelet therapy (DAPT) has been one of the mainstays in the treatment of patients who have suffered an acute myocardial infarction (AMI) or undergoing percutaneous coronary intervention... read more

Tags: hemorrhage, infarction, myocardial infarction, PCI, thrombosis,

Genetic Testing in Early-onset Atrial Fibrillation

Atrial fibrillation (AF) is a globally prevalent cardiac arrhythmia with significant genetic underpinnings, as highlighted by recent large-scale genetic studies. A prominent clinical and genetic overlap exists between AF,... read more

Tags: arrhythmia, atrial fibrillation, cardiomyopathy, diagnosis, study,

Ketamine Can Be a Transformational Agent But Not Without Risk or Danger

Ketamine is growing as a tool in the world of emergency medicine, offering a broad spectrum of applications that underscore its pivotal role in modern therapeutic regimens. It is increasingly being recognized for its potent... read more

Tags: ketamine, pain, pharmacology, therapy,

Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments

This systematic review and meta-analysis demonstrated the significant association of implementing sepsis alert systems in the Emergency Departments (ED) with patient outcomes. These findings indicate that sepsis alert systems... read more

Tags: ICU, infection, inflammation, sepsis, study,

Neurocritical Care for the Advanced Practice Clinician

By utilizing a review of case-based studies and providing concise management recommendations from leaders in the field, this book provides essential knowledge for those practicing in a dynamic specialty. In the rapidly developing... read more

Tags: book, education, ICU, neurology,

Fluid Accumulation Syndrome in Sepsis and Septic Shock

In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more

Tags: diagnosis, hypoxia, ICU, resuscitation, sepsis, septic shock, study, treatment,

BPRI and Clinical Outcomes in Patients with Septic Shock

Use of the novel dose-effect index, Blood Pressure Response Index (BPRI) was proposed to allow rapid bedside assessment of the reactivity of septic shock patients to vasoactive drugs, as isolated MAP or VIS cannot reflect... read more

Tags: ARF, BPRI, ICU, norepinephrine, prognosis, research, sepsis, septic shock, SOFA, study,

Collaborative Practice in Critical Care Settings

This practical and evidence-based workbook offers a series of assessment, implementation and evaluation activities for professionals working in critical care contexts. Designed to improve the quality of care delivery, it...

Essentials of Perioperative Nursing

Essentials of Perioperative Nursing, Sixth Edition is an essential reference for new perioperative nurses as well as experienced nurses who need a refresher. Succinct and easy to use, it addresses the basics associated with...