Disease Progression Associated Cytokines in COVID-19 Patients with Deteriorating and Recovering Health Conditions

Understanding the immune response to COVID-19 is challenging due to its high variability among individuals. To identify differentially expressed cytokines between the deteriorating and recovering phases, we analyzed the Electronic... read more

Tags: COVID-19, cytokine, diagnosis, infection, inflammation, mechanical ventilation,

Critical Care Administration: A Comprehensive Clinical Guide

This book provides a state-of-the-art overview on critical care administration. The text reviews important aspects and considerations involved in developing an efficient, cost-effective critical care program, while maintaining... read more

Tags: book, education, guidelines, ICU, tele-ICU,

Blood Eosinophils Matter in Post-COVID-19 Pneumonia

Preliminary results showed that a eosinophil increase during hospitalization could be a potential predictor of pulmonary sequelae in surviving patients after COVID-19 pneumonia. Despite the protective role of eosinophils,... read more

Tags: COVID-19, cytokine, infection, NIV, pneumonia, study,

A Retrospective Closed Cohort Study on Distribution of Multidrug-Resistant Bacteria in VAP and its Impact on Patient Outcome

Gram-negative organisms, particularly Klebsiella and Acinetobacter, were the main multidrug-resistant (MDR) ventilator-associated pneumonia (VAP) culprits. MDR-VAP exhibited higher morbidity and mortality. A study focused... read more

Tags: extubation, intubation, study, VAP, ventilation,

ICU Manual

This practical guide provides a multidisciplinary, clinically oriented approach to the management of patients in intensive care. The book discusses the complete range of specialties, including cardiology, pulmonology, gastroenterology,... read more

Tags: book, cardiology, diagnosis, education, ICU, neurology,

Ineffectiveness of Therapeutic Plasma Exchange – Last Resort in Severe COVID-19

Patients severely infected with SARS-CoV-2 showed fluctuations in inflammatory parameters despite TPE treatment; CRS was not suppressed by TPE; and this treatment did not confer survival benefit in this patient group. A total... read more

Tags: COVID-19, cytokine, infection, procalcitonin, study,

Oxygen Therapy and Noninvasive Respiratory Supports in Acute Hypoxemic Respiratory Failure

Whereas oxygen supplementation should be initiated for patients with acute hypoxemic respiratory failure defined as PaO2 below 60 mm Hg or SpO2 ... read more

Tags: COVID-19, HFNC, hypoxemia, intubation, NIV, oxygen, oxygenation,

COVID-19 Pneumonia: Different Respiratory Treatments for Different Phenotypes?

Type L and Type H patients are best identified by CT scan and are affected by different pathophysiological mechanisms. If not available, signs which are implicit in Type L and Type H definition could be used as surrogates:... read more

Tags: COVID-19, edema, inflammation, phenotypes, pneumonia, treatment,

Octenidine Bathing Effective in Preventing ICU-acquired Primary Bacteremia

EFFECT has demonstrated that octenidine is effective at preventing primary bacteremia. The emphasis lies among Gram-positive bacteria and common skin commensals. As part of a robust bundle strategy, octenidine can serve as... read more

Tags: bacteremia, hygiene, ICU, infection, study,

Practical Issues in Anesthesia and Intensive Care

The contents of this book are a selection taken from materials that have been developed during the preparation of continuing education courses (distance learning), whose scientific advisor is the volume editor, Professor... read more

Tags: book, cardiology, education, hemodynamics, nephrology,

CDC Reports Rising Levels of Mycoplasma Pneumonia and RSV in Young Kids

Though the nation’s respiratory disease levels remain low overall, with COVID levels declining and little sign of a flu uptick, illnesses caused by Mycobacterium pneumoniae are increasing, especially in children, and respiratory... read more

Tags: CDC, flu, infection, pediatrics, pneumonia,

Distinct Immune Profiles and Clinical Outcomes in Sepsis Subphenotypes Based on Temperature Trajectories

Sepsis subphenotypes identified using the universally available measurement of body temperature had distinct immune profiles. Hypothermic patients, who had the highest mortality rate, also had the lowest levels of most pro-... read more

Tags: anti-inflammatory, coagulation, infection, inflammation, sepsis, study,

The Impact of COVID-19 Pandemic on Respiratory Syncytial Virus Infection in Children

We observed a lower incidence of RSV infection and a lower rate of hospitalization for RSV during the COVID-19 pandemic. The second RSV season during the COVID-19 pandemic began earlier, lasted longer, and had a lower frequency.... read more

Tags: COVID-19, infection, pediatrics, virus,

Advances in Critical Care Pediatric Nephrology: Point of Care Ultrasound and Diagnostics

The book covers advances in critical care pediatric nephrology, including care of sick children with acute kidney injury. The book contains detailed guidance on point of care ultrasound in children with acute kidney injury... read more

Tags: book, CRRT, diagnostics, nephrology, pediatrics, ultrasound,

Adjusting risk of AKI for Time on Controlled Mechanical Ventilation in ARDS

The authors expressed concerns that the study did not account for certain key covariates, such as septic shock, right heart failure, or hypoxemia, which are believed to influence the development of AKI. We would like to clarify... read more

Tags: AKI, ARDS, hypoxemia, septic shock, vasopressors,

Accuracy of Continuous Glucose Monitoring Systems in ICU Patients

In this scoping review of CGM accuracy in the ICU, we found great diversity in accuracy reporting. Accuracy varied depending on CGM and comparator, and may be better for intravascular CGM and potentially lower during hypoglycemia.... read more

Tags: glucose, ICU, monitoring, study,

UFNET Fluid Removal Strategy Secured by Hemodynamic Monitoring vs. Standard of Care in patients with CRRT

An early and active UFNET strategy secured by an advanced hemodynamic protocol using dynamic indices of preload dependence had the capacity to control H72 FB in an ICU population of patients with acute circulatory failure,... read more

Tags: CRRT, hemodynamics, hypotension, hypovolemia, monitoring, SOFA, tachycardia, trial, vasopressors,

Priorities in Critical Care Nursing

With its succinct coverage of all core critical care nursing topics, this evidence-based text is the perfect resource for both practicing nurses and nursing students alike. Using the latest, most authoritative research, this...

The PICU Handbook

The PICU Handbook is a unique, portable compilation of the information essential for residents and fellows to successfully navigate the modern Level 1 and Level 2 pediatric intensive care unit (PICU). Enhanced by numerous...