Issue #319 - View in the Browser

CRITICAL CARE NEWS

LATEST NEWS FOR CRITICAL CARE PROFESSIONALS

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Beyond SOFA: Sepsis ImmunoScore Redefines Risk Stratification for Mortality and ICU Admission

This multicenter observational study involving over 6,000 adult patients found that the Sepsis ImmunoScore, an AI-based tool, significantly outperformed six conventional clinical scores and biomarkers in predicting sepsis,... read more

Tags: AI, biomarkers, CRP, ICU, infection, mortality, prediction, procalcitonin, qSOFA, sepsis, SIRS, SOFA, study,


Handbook of Critical and Intensive Care Medicine

The latest edition of this handbook is a concise yet comprehensive guide for attending physicians, fellows, residents, and students who cover the ICU. The chapters follow an outline format and are divided by organ system,... read more

Tags: book, education, ICU, trauma,

Handbook of Critical and Intensive Care Medicine

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Why Early mHLA-DR Fails and Dynamic Monitoring is Key to Immunosuppression in Septic Shock

This 20-year study of 1,023 septic shock patients confirms that the immune marker mHLA-DR is a robust biomarker for identifying the most immunosuppressed patients who face a higher risk of death and ICU-acquired infections.... read more

Tags: biomarkers, ICU, immunosuppression, inflammation, monitoring, mortality, research, sepsis, septic shock, study,


Handbook of Intravenous Fluids

This easy to use pocket book covers all aspects of intravenous fluid therapy in critically ill patients from applied physiology to bedside clinical management succinctly. It includes updated and evidence-based content on... read more

Tags: book, education, resuscitation, therapy, trial,

Handbook of Intravenous Fluids

Septic Shock MAP Targets: Homogeneous Response, Heterogeneous Harm

This study, which analyzed 776 patients with septic shock, found that overall, there was no significant difference in the response (no heterogeneity) to different blood pressure targets, particularly concerning the primary... read more

Tags: mortality, norepinephrine, sepsis, septic shock, study, treatment,


The Power and Pitfalls of AI: GPT Masters ICU Prediction But Struggles with ED Discharge

This retrospective proof-of-concept study investigated GPT-4o’s ability to predict disposition (admission vs. discharge) for high-acuity ED patients with complex respiratory cases who required pulmonology consultation... read more

Tags: AI, angiography, COPD, diagnostics, embolism, ICU, prediction, pulmonary embolism, study, technology, triage,


Handbook for Venous Thromboembolism

A truly practical guidebook for anyone who needs the key information on the diagnosis, management and prevention of venous thromboembolism. Specific areas of focus include understanding the risk factors for VTE and the role... read more

Tags: anticoagulants, diagnosis, DVT, thromboembolism, treatment, VTE,

Handbook for Venous Thromboembolism

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Mapping the Brain’s Blueprint: Precision Critical Care for Acute Brain Injury

Current management strategies for complex ABI conditions—which are associated with high mortality and morbidity—often rely on a “one-size-fits-all” approach derived from trials on heterogeneous patient populations.... read more

Tags: ABI, biomarkers, brain injury, monitoring, morbidity, phenotypes, treatment,


Individualizing PEEP in Acute Brain Injury

The consensus is that Positive End-Expiratory Pressure (PEEP) can be safely used in most patients with Acute Brain Injury (ABI), provided its effects on the brain are closely monitored. PEEP Safety and ICP: While PEEP can... read more

Tags: ABI, brain injury, hypertension, hypoxemia, ICP, inflammation, PEEP, research, vasoconstriction,


Epinephrine or Norepinephrine? The Vasoactive Face-Off in Pediatric Septic Shock

This prospective observational study compared the clinical outcomes of epinephrine (adrenaline) versus norepinephrine (noradrenaline) as the initial vasoactive agent in pediatric septic shock. Study Population: 68 children... read more

Tags: epinephrine, norepinephrine, pediatrics, picu, resuscitation, sepsis, septic shock, study,


Echocardiography for Intensivists

This book contains all the information that readers will require in order to perform echocardiography and to interpret the findings correctly. After an introductory chapter on the essential physics of ultrasonography, standard... read more

Tags: book, ICU, ultrasonography, ultrasound,

Echocardiography for Intensivists

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The MAP-SEPS Protocol: A New Frontier in Detecting Early Sepsis by Targeting Microcirculation

The MAP-SEPS trial is a prospective observational study designed to determine if a comprehensive, multimodal approach to peripheral perfusion monitoring can improve the early detection of sepsis and organ failure in critically... read more

Tags: CRT, ICU, infection, mechanical ventilation, perfusion, research, sepsis, septic shock, study, trial,


Lactate Fails to Boost Predictive Power in Post-Op Cardiac Patients

This retrospective study analyzed over 2,500 adult patients to determine if lactate dynamics—including clearance time, trend, and maximum level—offer incremental value in predicting poor outcomes after cardiac surgery,... read more

Tags: biomarkers, cardiology, hyperlactatemia, lactate, stroke, study, surgery,


Handbook of ICU Therapy

This popular handbook provides a practical guide to managing common and important problems in the critically ill patient, as well as sufficient background information to enable understanding of the principles and rationale... read more

Tags: book, education, ICU, therapy,

Handbook of ICU Therapy

Medication Management: Spontaneous vs. Traumatic Intracerebral Hemorrhage (sICH vs. tICH)

Pharmacological management for BP control and seizure prophylaxis differs between tICH and sICH. ICH etiology should be accounted for in determining appropriate BP goals and the necessity of seizure prophylaxis. Intracerebral... read more

Tags: AKI, angiopathy, anticoagulation, CPP, hemorrhage, hypertension, ICH, ICU, seizure, TBI, treatment,


CRITICAL CARE JOKES and MEMES

Get a much-needed dose of laughter with our new joke/meme section tailored for critical care professionals. Do you have a joke or meme about critical care medicine you'd like to share? Send us your best one!

ICU Admission Criteria

A new resident bursts into the ICU, frantically looking for a nurse. He finally spots one charting and says, “Quick! I need to know the official ICU admission criteria!”
The nurse looks up with a completely deadpan expression and replies, “Simple, Doctor. It’s when the patient is too sick for the floor, but not quite sick enough for the doctor to have to talk to the family.”

See More Critical Care Jokes and Memes

NEW MEDICAL DEVICES

Discover new cutting-edge medical devices that are revolutionizing patient care and improving outcomes in the ICU. Did your ICU recently adopt a new medical device? We want to hear about it!

Clave IV Connectors

The new FDA 510(k) regulatory clearance for ICU Medical’s Clave portfolio of Needlefree IV Connectors allows for a new labeling claim highlighting peer-reviewed study data. This data suggests that acute care hospitals standardizing on Clave technology and utilizing the Needlefree IV Connectors in high volumes may achieve a 19% lower relative risk of Central Line-Associated Bloodstream Infection (CLABSI), along with associated benefits of lower healthcare costs and reduced mortality, compared to non-Clave hospitals.

Clave IV Connectors

The use of the Clave NCT, in and of itself, is an effective risk reduction strategy for CLABSI prevention, reduced mortality, and substantial cost savings.

In addition to the CLABSI reduction statement, ICU Medical’s instructions for use included with these products will also reflect enhanced attributes, including use with blood with no required changeout after infusion or aspiration, and the prevention of microbial ingress for seven days.

Learn More

See More New Medical Devices

LATEST CRITICAL CARE PODCASTS

Every week we scour the web to bring you the latest podcast episodes related to ICU and Critical Care Medicine. Here are the latest podcasts:

Humanizing the Neuro ICU with Compassion, Teamwork, and Verticalization Therapy
With the complex mobility needs of patients in the neuro ICU, how did Dr. Tarek Dakakni standardize patient standing for 8 hrs a day as a standard? As acting medical director, how did Dr. Dakakni bring all disciplines together to customize care and optimize outcomes for each patient as a person? Dr. Dakakni joins us now to share how the ABCDEF bundle looks in his Neuro ICU. Listen to podcast

MELLOW, Melatonin, and Mailbag
We talk about melatonin! We highlight MELLOW because it has the best acronym (by Burry et al in CHEST 2025). Then we dive into our mailbag! Listen to podcast

Anatomy for Lumbar Puncture
In this episode, we discuss the anatomy for the lumbar puncture and compare the differences between adult and pediatric populations. Listen to podcast

See More Podcasts

CRITICAL CARE UPCOMING EVENTS

ANESTHESIOLOGY 2025
Oct. 10, 2025 - San Antonio, TX

With topics for every member of the care team, every career stage, and every clinical area, the ANESTHESIOLOGY annual meeting makes it easy and engaging to advance your skills and knowledge.


LIVES 2025
Oct. 25, 2025 - Munich, Germany

In 2025, we invite you once again to join for 5 eventful days, between 25 and 29 October, for pre-congress educational courses, scientific sessions and educational workshops.


2025 Tri-Society Cardiac & Thoracic Symposium
Nov. 19, 2025 - Sydney, Australia

2025 Tri-Society Cardiac & Thoracic Symposium (3SCTS) which is a combined scientific meeting of three Australasian cardiothoracic societies: anaesthesia (ANZCA), surgery (ANZCTS), and perfusion (ANZCP).


See More Events

NEW CRITICAL CARE JOBS

Intensivist Physician
White Plains, New York
White Plains Hospital is seeking a full-time Intensivist Physician to join its expanding Critical Care service line. As a key member of the multidisciplinary ICU team, the Intensivist will work in a 24/7 model alongside Advanced Practice Providers, managing a diverse range of complex Medical, Surgical, Neurologic, and Cardiac cases.

Cardiac Intensivist Fellow
Hollywood, Florida
The Memorial Cardiac and Vascular Institute at Memorial Healthcare System is seeking a BE/BC critical care physician for a fellow position. The fellowship is a one-year, non-ACGME program that will provide exposure to all aspects to care for cardiac surgery patients.

Pulmonary/Critical Care Physician
Indianapolis, Indiana
IU Health Physicians is seeking a Pulmonary/Critical Care Physician to join their exceptional team at IU Health University Hospital. The Division of Pulmonary and Critical is affiliated with the Indiana University School of Medicine.

See More Jobs

FEATURED CRITICAL CARE BOOKS

Principles of Pulmonary Medicine

With an emphasis on the pathophysiologic basis of pulmonary disease, Principles of Pulmonary Medicine, 7th Edition, by Drs. Steven E Weinberger, Barbara A Cockrill, and Jess Mandel, provides a superbly illustrated introduction...

Read More
Principles of Pulmonary Medicine

Erasing Death: The Science That Is Rewriting the Boundaries Between Life and Death

Dr. Sam Parnia, Director of the AWARE Study (AWAreness during REsuscitation) and one of the world’s leading experts on the scientific study of death and near-death experiences (NDE), presents cutting-edge research from...

Read More
Erasing Death: The Science That Is Rewriting the Boundaries Between Life and Death

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