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Issue #328 - View all issues

CRITICAL CARE NEWS

LATEST NEWS FOR CRITICAL CARE PROFESSIONALS

Vasopressin vs. Norepinephrine in Neonatal Septic Shock

A retrospective multi-center study analyzed the use of vasopressin (VA) and norepinephrine (NE), two distinct pressors, in 58 neonates with warm septic shock across three Canadian Level-III NICUs between 2015 and 2020. The... read more

Tags: NICU, norepinephrine, pediatrics, septic shock, study, vasopressin,


Sepsis Management: PIRO and MODS

This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent... read more

Tags: antibiotics, book, infection, MODS, sepsis, treatment,

Sepsis Management: PIRO and MODS

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Obesity Paradox or Myth? BMI Shows No Impact on Sepsis Survival in ICU Patients

This retrospective cohort study examined the association between body mass index (BMI) and clinical outcomes in 559 adult ICU patients with sepsis admitted between January 2021 and December 2023. Patients were categorized... read more

Tags: ARDS, ICU, LOS, mortality, obesity, sepsis, septic shock, vasopressors, ventilation,


Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their... read more

Tags: biomarkers, book, research, sepsis, trauma, treatment,

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

Less Steroids, Better Outcomes: High-Dose Corticosteroids Harm ICU COPD Patients

A large pharmacoepidemiologic cohort study of over 17,000 US patients admitted directly to ICUs for acute exacerbations of COPD revealed that two-thirds received high-dose systemic corticosteroids (>240 mg/day methylprednisolone... read more

Tags: COPD, corticosteroids, hyperglycemia, ICU, mechanical ventilation, steroids, study,


Hemodynamic Monitoring Using Echocardiography in the Critically Ill

The hemodynamic evaluation of patients with acute circulatory failure and respiratory failure has in the past usually been performed using invasive procedures but in recent years less invasive monitoring devices have been... read more

Tags: book, diagnosis, echocardiography, education, hemodynamics, monitoring, trauma,

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

Norepinephrine at Extubation: No Weight-Related Reintubation Risk

This multicenter cohort study investigated the association between the use of norepinephrine at the time of extubation and the rate of reintubation within 7 days in critically ill patients, with a specific focus on those... read more

Tags: extubation, ICU, intubation, norepinephrine, obesity,



Triumph Over Sepsis: Dramatic Mortality Decline in ANZ ICUs, With a Post-2020 Rebound

In a comprehensive analysis of over 2.9 million ICU admissions across 219 Australian and New Zealand intensive care units from 2000 to mid-2023, in-hospital mortality for adult patients with sepsis (per Sepsis-3 criteria)... read more

Tags: COVID-19, ICU, mechanical ventilation, mortality, sepsis, septic shock, study,


Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover... read more

Tags: book, corticosteroids, inflammation, pediatrics, treatment,

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

AI Foresees the Squeeze: Machine Learning Predicts Vasopressor Needs Hours Ahead in Sepsis Patients

This proof-of-concept retrospective study, utilizing the MIMIC-IV v2.2 database (2008–2019), demonstrates that an interpretable machine learning model based on routinely collected electronic health record data from ICU... read more

Tags: AI, hemodynamics, ICU, lactate, sepsis, SOFA, technology, vasopressors,


Taming the Physiologically Difficult Airway: Safer Intubation in Critically Ill Adults

Tracheal intubation is a frequent and high-risk procedure in critically ill adults, with a global study of nearly 3,000 patients revealing major peri-intubation adverse events in 45% of cases—primarily cardiovascular collapse... read more

Tags: airway, Airway Management, hemodynamics, hypoxemia, ICU, laryngoscopy, oxygenation, study,



4D Trial Unlocks Calm: Dexmedetomidine Eases Hyperactive Delirium in Non-Intubated ICU Patients

The 4D randomized clinical trial, a multicenter, double-blind, placebo-controlled study conducted across nine ICUs, investigated the effectiveness of continuous intravenous dexmedetomidine infusion versus placebo in non-intubated... read more

Tags: agitation, bradycardia, delirium, dexmedetomidine, hypotension, ICU, intubation, sedation, trial,


Sodium Levels and Sepsis-Related Liver Injury: A Threshold Effect

A retrospective cross-sectional study utilizing data from the MIMIC-IV database explored the relationship between serum sodium (SNa) levels and the risk of Sepsis-Related Liver Injury (SRLI) in 11,809 adult ICU patients with... read more

Tags: cirrhosis, ICU, lactate, liver, liver injury, sepsis, sodium, study,


Blood Pressure Disorders in Acute and Chronic Kidney Diseases (Updates in Hypertension and Cardiovascular Protection)

This new book is intended to be an in-depth and up-to-date guide to the various aspects of the association between blood pressure disorders and acute/chronic renal diseases. In addition, this work includes discussion of topics... read more

Tags: AKI, book, education, hypertension, ICU, nephrology,

Blood Pressure Disorders in Acute and Chronic Kidney Diseases (Updates in Hypertension and Cardiovascular Protection)

Urinary Source Saves Lives: Why Infection Origin Matters in Septic Shock for Patients Over 90

In critically ill nonagenarians and centenarians admitted to ICUs with septic shock, the source of infection emerges as a key independent predictor of long-term survival, varying over time. Patients with septic shock from... read more

Tags: anticoagulation, coagulation, ICU, infection, sepsis, septic shock, SOFA, ventilator,


Refining Neuromuscular Blockade Use in ARDS

Acute Respiratory Distress Syndrome (ARDS) remains a critical challenge in medicine, persistently linked to mortality rates exceeding 30% despite extensive research over the years. The lack of effective drug treatments means... read more

Tags: ARDS, corticosteroids, ICU, infusion, oxygenation, PEEP, rehabilitation, research, treatment,


Oral Levothyroxine: A Life-Saving Alternative for Myxedema Crisis

An observational study analyzing 12 adult patients (median age 66, 50% female) diagnosed with myxedema coma at a tertiary center between 2011 and 2021 highlights the efficacy of high-dose oral levothyroxine as a viable treatment,... read more

Tags: hypothyroidism, ICU, study, treatment, vasopressors,


The Dangerous Duo: How Delirium Compounds Risks in Acute Kidney Injury

This systematic review and meta-analysis of over 158,000 critically ill patients reveals a significant link between Acute Kidney Injury (AKI) and delirium, affecting approximately 32% of patients with AKI. The study found... read more

Tags: AKI, creatinine, delirium, ICU, study,


Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple

A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex, acid-base, fluid, and electrolyte problems. Useful to medical students, interns and residents, nurses... read more

Tags: book, education, electrolytes, nephrology, therapy,

Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple

The Pressure to Survive: Why Peak BP Matters for the Oldest ICU Patients

This binational cohort study analyzed 219 patients aged 90 and older who were admitted to the ICU following an in-hospital cardiac arrest. While clinical focus often shifts to average or minimum blood pressure, this research... read more

Tags: blood pressure, hypotension, ICU, IHCA, research, study,


JOKES/MEMES

Get a much-needed dose of laughter with our new joke/meme section tailored for critical care professionals. Do you have a joke or meme about critical care medicine you'd like to share? Send us your best one!

First Child

A man rushes into a hospital and yells at the receptionist, “Help! My wife is pregnant and her contractions are only two minutes apart!”
“Is this her first child?” the receptionist asks calmly.
“No, you idiot!” the man screams. “This is her husband!”

See More Critical Care Jokes and Memes

NEW MEDICAL DEVICES

Discover new cutting-edge medical devices that are revolutionizing patient care and improving outcomes in the ICU. Did your ICU recently adopt a new medical device? We want to hear about it!

Brain Anesthesia Response Monitor (BARM) by Cortical Dynamics

BARM: The Future of Surgical Brain Monitoring and Anesthesia Precision

BARM is an innovative Australian technology that provides real-time measurement of both the patient’s unconsciousness and pain levels during surgery.

Core Function: It offers anesthesiologists precise data on brain activity, allowing them to optimize sedation and analgesia (pain relief).

Brain Anesthesia Response Monitor (BARM) by Cortical Dynamics

Key Benefits:

Enhanced Patient Safety: Ensures patients receive the exact, appropriate level of sedation.

Reduced ICU Stays: Helps prevent over-sedation, which can potentially shorten mechanical ventilation times and overall ICU stays.

Improved Outcomes: Supports a stable surgical process, contributing to better patient stability and outcomes.

Significance: BARM is presented as a leap forward, setting a new standard for surgical monitoring by providing a crucial window into brain response during procedures.

Learn More

See More New Medical Devices

LATEST CRITICAL CARE PODCASTS

Every week we scour the web to bring you the latest podcast episodes related to ICU and Critical Care Medicine. Here are the latest podcasts:

Biofeedback vs Respiratory Retraining for Inducible Laryngeal Obstruction
Interview with Molly N. Huston, MD, and William A. Strober, MD, MSCI, authors of Biofeedback vs Respiratory Retraining for Inducible Laryngeal Obstruction: A Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Listen to podcast

Resus Nurse Efficiency
In this episode, Scott sits down with Candice to unpack how experienced emergency resus nurses manage overwhelming workloads in real-world conditions. Listen to podcast

ASCVD Risk & Lipids Update! PREVENT, ApoB, Lp(a) + Next-Gen Therapies
Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. Listen to podcast

See More Podcasts

CRITICAL CARE UPCOMING EVENTS

8th Digital Critical Care Datathon
Jan. 09, 2026 - Online

This 8th Critical Care Datathon is a great event where multidisciplinary teams and international experts collaborate to explore clinical questions using large datasets from electronic health records.


Critical Care Ultrasound: Pediatric and Neonatal
Jan. 20, 2026 - Chicago, Illinois

Increase your ultrasound diagnostic skills and scanning proficiency with the Critical Care Ultrasound: Pediatric and Neonatal course. On completion, participants will be able to immediately integrate their learned skills into clinical practice.


Intensive Care Innovation Forum
Feb. 05, 2026 - Amsterdam, The Netherlands

This event brings together an exceptional international faculty to explore how innovation, technology, and design are reshaping ICU practice.


See More Events

NEW CRITICAL CARE JOBS

Pulmonary/Critical Care Physician Trained in Pulmonary Hypertension
Indianapolis, Indiana
We are seeking a highly skilled and compassionate pulmonary and critical care trained physician who is specialized in pulmonary hypertension who will work with our nationally recognized multidisciplinary pulmonary vascular disease program.

Pulmonary and Critical Care Physician
Fishers, Indiana
IU Health Physicians is seeking a Pulmonary/Critical Care Physician to join their exceptional team at IU Health North Hospital. The Division of Pulmonary and Critical is affiliated with the Indiana University School of Medicine. This practice has a diverse group of providers as well as patients in a suburban area.

Pulmonary Critical Care Physician
Fort Wayne, Indiana
Indiana University Health, Indiana's most comprehensive and top-ranked healthcare system is actively recruiting Pulmonary/Critical Care Physician to join our highly skilled team of physicians and advanced practice providers in suburban Fort Wayne, Indiana.

See More Jobs

FEATURED CRITICAL CARE BOOKS

Evolving Crisis Standards of Care and Ongoing Lessons from COVID-19

Crisis Standards of Care (CSC) inform decisions on medical care during a large-scale crisis such as a pandemic or natural disaster, eliminating the need to make these decisions at the bedside without protections or guidance....

Read More
Evolving Crisis Standards of Care and Ongoing Lessons from COVID-19

Hemodynamic Monitoring Made Easy: Mastering Critical Care Skills for Nurses and Clinicians

This thorough, simple-to-follow book was created especially for critical care nurses, clinicians, and other healthcare workers to help you fully utilize hemodynamic monitoring. With its straightforward, methodical approach...

Read More
Hemodynamic Monitoring Made Easy: Mastering Critical Care Skills for Nurses and Clinicians

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