Septic Shock Metabolic Subgroups and Clinical Outcome
Three metabolic clusters exist in patients with septic shock with most metabolites differing between clusters and lipid species being most influential. Cluster proportions evolved over time with a high metabolite group... read more
Blood Pressure Disorders in Acute and Chronic Kidney Diseases (Updates in Hypertension and Cardiovascular Protection)
This new book is intended to be an in-depth and up-to-date guide to the various aspects of the association between blood pressure disorders and acute/chronic renal diseases. In addition, this work includes discussion... read more
The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees
This new book will serve as a useful resource for all pharmacists involved in the management of critically ill patients, whatever their level of experience and training. There are few textbooks aimed specifically at critical... read more
VAP Recurrences Definition: European Experts Consensus
This consensus by European experts proposes four different ventilator-associated pneumonia (VAP) recurrence entities which should facilitate the harmonization of recurrence criteria for clinical practice and future studies. Thirty-six... read more
Sepsis: Staging and Potential Future Therapies
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Variability in pathogenesis and complex pathophysiology often delay diagnosis and create significant challenges for clinical... read more
Early Initiated Noradrenaline vs. Fluid Therapy for Hypotension and Shock
The VASOSHOCK trial is a pragmatic, multi-center, superiority, randomized controlled trial investigating early initiation of peripheral noradrenaline in hypotension and shock, investigating the impact of this treatment on... read more
Management of ARDS COVID-19 Patients Using Hemoperfusion and CRRT
Combined hemoperfusion (HP) and continuous renal replacement therapy (CRRT) hold promise as a potential intervention for severe COVID-19 cases with multiple organ dysfunction, leading to improved clinical outcomes. Fifty-six... read more
Rapid Clinical Effects of Convalescent Plasma Therapy in Severe COVID-19 ARDS
Administration of convalescent plasma (CP) in critically ill COVID-19 patients leads to a rapid and highly significant improvement of sequential organ failure assessment (SOFA) score along with improvements in respiratory... read more
Fluid Management Impact on Outcomes in Sequential Extracorporeal Support
Sepsis is a life-threatening condition characterized by dysregulated inflammatory responses, often leading to multiple organ dysfunction and high mortality rates. Continuous renal replacement therapy (CRRT) and extracorporeal... read more
Mortality in Patients with SA-AKI Using the MIMIC-III Database
In this study, we identified critical factors influencing mortality in patients with Sepsis-Induced Acute Kidney Injury (SA-AKI) using the MIMIC-III database. The primary findings of our research, including advanced age,... read more
Mechanical Ventilation in Patient with Respiratory Failure
This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more
VA-ECMO and Pulmonary Reperfusion
The study by Stadlbauer and colleagues provides further evidence that veno-arterial extracorporeal membrane oxygenation (VA-ECMO) should—whenever necessary—be used, as a bridge to pulmonary reperfusion, but not as a bridge... read more
Severe Adenoviral Infections: Disease Progression and Poor Prognostic Markers
Low hemoglobin, high serum ferritin, and high LDH in the second week are markers of disease progression and poor prognostic markers in severe adenoviral infections, emphasizing further research and targeted interventions. The... read more
Leptin and Linterlukin-6 Relationship and Influence of Mortality in Sepsis
High leptin levels might counteract the adverse prognostic effect of elevated IL-6 on septic mortality. At the same IL-6 level, leptin could predict septic mortality. Leptin might be a protecting factor for men and gender-different... read more
Continuous Glucose Monitoring-Based Insulin Titration Protocol for Type 2 Diabetes Patients
The continuous glucose monitoring (CGM)-based insulin titration protocol by Olsen et al has been successfully implemented for titrating basal, prandial, and correctional insulin in inpatients with type 2 diabetes in non-ICU... read more
Increased Sodium Levels Associated with Ceftriaxone Administration
Serum sodium elevation is considered a frequent manifestation in critically ill patients, with significant clinical outcomes and requiring timely management. This case report suggests a possible association between the... read more
Lung-protective Ventilation Strategies for Mechanical Ventilation
This study is an important step toward optimizing mechanical ventilation strategies, addressing the interplay between mechanical power, gas exchange and long-term respiratory outcomes could further refine lung-protective... read more
Glycemic Control Role in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19
This study demonstrates that among hospitalized COVID-19 patients with type 2 diabetes mellitus, poor glycemic control (HbA1c ≥ 7%) correlates with increased systemic inflammation, greater disease severity, and worse clinical... read more
ECMO in the Adult Patient (Core Critical Care)
Extracorporeal membrane oxygenation (ECMO) is developing rapidly, and is now part of the toolkit for the management of all patients with severe respiratory or cardiac failure. Clinicians of all disciplines are in need of... read more
Dynamic Left Ventricular Outflow Tract Obstruction Induced by IABP in Patient with Angioedema
Mechanical circulatory support with intra-aortic balloon pump (IABP) can aid in the treatment of cardiogenic shock but may rapidly become detrimental due to the reduction in systolic arterial afterload in patients with predispositions... read more
Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple
A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex, acid-base, fluid, and electrolyte problems. Useful to medical students, interns and residents, nurses... read more
