Quality Improvement Initiatives in Sepsis in an Emerging Country

Quality Improvement Initiatives in Sepsis in an Emerging Country

This quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private... read more

Utility and Diagnostic Accuracy of Bedside Lung Ultrasonography During MET

Utility and Diagnostic Accuracy of Bedside Lung Ultrasonography During MET

Lung ultrasonography can be rapidly performed in the majority of patients with MET activation for respiratory deterioration. As an independent diagnostic test, lung ultrasonography is non-inferior to the medical emergency... read more

Preventing Harm in the ICU – Building a Culture of Safety and Engaging Patients and Families

Preventing Harm in the ICU – Building a Culture of Safety and Engaging Patients and Families

Preventing harm remains a persistent challenge in the ICU despite evidence-based practices known to reduce the prevalence of adverse events. This review seeks to describe the critical role of safety culture and patient and... read more

Technologic Distractions

Technologic Distractions

Summary of Approaches to Manage Alert Quantity With Intent to Reduce Alert Fatigue and Suggestions for Alert Fatigue Metrics. Approaches for managing alert fatigue in the ICU are provided as a result of reviewing tested interventions... read more

Clinicians’ Perception and Experience of Organ Donation From Brain-Dead Patients

Clinicians’ Perception and Experience of Organ Donation From Brain-Dead Patients

ICU clinicians are primarily involved in organ donation after brain death of ICU patients. Their perceptions of organ donation may affect outcomes. Our objective was to describe ICU clinician’s perceptions and experience... read more

Unplugged & Reconnected – Recovering from Burnout

Unplugged & Reconnected – Recovering from Burnout

Does your desk ever look like this? Mine does. WAY too often. Insert the piles of papers, books, journals and mail I need to get to on the side also. When I look at this photo, it seems absolutely ridiculous. Why on earth... read more

Noninvasive Ventilation in Patients With Hematologic Malignancy

Noninvasive Ventilation in Patients With Hematologic Malignancy

Two-thirds of patients with Hematologic Malignancy and respiratory failure failed Noninvasive Ventilation (NIV) and required endotracheal intubation, and had high subsequent mortality. Patients who failed NIV had higher Paco2,... read more

5-Year Trends of Critical Care Practice and Outcomes

5-Year Trends of Critical Care Practice and Outcomes

According to researchers in the U.S., analyses of patients, practices, and outcomes from a large geographically dispersed sample of adult ICUs revealed trends of increasing age and acuity, higher rates of adherence to best... read more

Early Troponin I in Critical Illness and its Association with Hospital Mortality

Early Troponin I in Critical Illness and its Association with Hospital Mortality

TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more

Benzodiazepines and Delirium in ICU Patients

Benzodiazepines and Delirium in ICU Patients

We have learned an extraordinary amount about ICU delirium over the last 2 decades, which is associated with increased duration of mechanical ventilation, length of hospital stay, long-term cognitive impairment, and mortality... read more

An Alternative Consent Process for Minimal Risk Research in the ICU

An Alternative Consent Process for Minimal Risk Research in the ICU

Seeking consent for minimal risk research in the ICU poses challenges, especially when the research is time-sensitive. Our aim was to determine the extent to which ICU patients or surrogates support a deferred consent process... read more

The Lactate Dilemma

The Lactate Dilemma

After a long and exhausting discussion with an inferior human being, a cardiologist, which happens to be an old friend, I decided to write some thoughts about lactate. So, I'll do like I do in my lectures, which is state... read more

Association Between Survival and Time of Day for RRT Calls

Association Between Survival and Time of Day for RRT Calls

Rapid response team activation is less frequent during the early morning and is followed by a spike in mortality in the 7 AM hour. These findings suggest that failure to rescue deteriorating patients is more common overnight.... read more

Selepressin – An Effective Substitute for Norepinephrine

Selepressin – An Effective Substitute for Norepinephrine

Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients. Vasopressin is widely used for vasopressor... read more

NIH Herpesvirus Study Leads to Discovery of Potential Broad-Spectrum Antiviral

NIH Herpesvirus Study Leads to Discovery of Potential Broad-Spectrum Antiviral

Scientists studying how regulated herpes simplex virus (HSV) infection unexpectedly found that inhibiting EZH2/1 suppressed viral infection. The research group, from the National Institute of Allergy and Infectious Diseases... read more

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause metastatic or... read more

Mastering Intensive Care

Mastering Intensive Care

Is the patient the centre of every action you take in the ICU? Do you exude calm and enthusiastic energy and greet other team members warmly and genuinely? Do you seek pleasure in seeing colleagues grow to become more skilled... read more