Why and How to Open ICU to Family Visits During the Pandemic

Why and How to Open ICU to Family Visits During the Pandemic

Since the lockdown because of the pandemic, family members have been prohibited from visiting their loved ones in hospital. While it is clearly complicated to implement protocols for the admission of family members, we believe... read more

Higher Level of Mobilization Improves Health Status

Higher Level of Mobilization Improves Health Status

In critically ill survivors, achieving higher levels of mobilization, but not increasing the number of active mobilization sessions, improved health status 6 months after ICU admission. The dosage of mobilization in ICU... read more

COVID-19 Pathophysiology: Looking Beyond Acute Disease

COVID-19 Pathophysiology: Looking Beyond Acute Disease

Careful descriptions of the clinical features of acute disease in patients infected with the novel coronavirus SARS-CoV-2 had begun to emerge before WHO declared the outbreak of COVID-19 a public health emergency of international... read more

Severity of Hypoxemia may Explain Indeterminate Results in Pediatric Trials of iNO

Severity of Hypoxemia may Explain Indeterminate Results in Pediatric Trials of iNO

Inhaled nitric oxide (iNO) is used for refractory hypoxemia in acute respiratory distress syndrome (ARDS) via vasodilation of pulmonary arterioles to ventilated alveoli, particularly in pediatrics. However, iNO has not affected... read more

COVID-19 ARDS has higher EVLWi and PVPI values than non-COVID-19 ARDS

COVID-19 ARDS has higher EVLWi and PVPI values than non-COVID-19 ARDS

Compared to acute respiratory distress syndrome (ARDS) patients without COVID-19, patients with COVID-19 had similar lung mechanics, but higher extravascular lung water index (EVLWi) and pulmonary vascular permeability index... read more

Steer Clear of Magnesium for COPD

Steer Clear of Magnesium for COPD

Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more

Quantitative Characterization of LV Function During Pulseless Electrical Activity Using Echocardiography

Quantitative Characterization of LV Function During Pulseless Electrical Activity Using Echocardiography

Left ventricular function measured by LVFS is positively correlated with higher probability of rates of return of spontaneous circulation (ROSC) and may be associated with higher chances of survival in patients with PEA arrest. We... read more

Textbook of Cardiorenal Medicine

Textbook of Cardiorenal Medicine

This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings... read more

Neurological Complications Acquired During Pediatric Critical Illness

Neurological Complications Acquired During Pediatric Critical Illness

Graphical models that include biomarkers in addition to clinical data are promising methods to evaluate direct relationships in the development of neurologic complications in critically ill children. Future work is required... read more

The Predictive Role of Combined Cardiac and Lung Ultrasound in COVID-19

The Predictive Role of Combined Cardiac and Lung Ultrasound in COVID-19

In hospitalized patients with coronavirus disease 2019, a very limited echocardiographic examination is sufficient for outcome prediction. The addition of echocardiography in patients with high-risk MEWS decreases the rate... read more

Clinical Companion in Nephrology

Clinical Companion in Nephrology

The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes... read more

NIV After Early Extubation Reduces Total Days Spent on i-MV

NIV After Early Extubation Reduces Total Days Spent on i-MV

Patients recovering from an episode of hypoxemic acute respiratory failure (hARF) may benefit from a weaning strategy based on early extubation followed by immediate noninvasive ventilation (NIV) application. Compared... read more

Risk of Clinical Severity by Age and Race/Ethnicity Among Adults Hospitalized for COVID-19

Risk of Clinical Severity by Age and Race/Ethnicity Among Adults Hospitalized for COVID-19

Older adults and people from certain racial and ethnic groups are disproportionately represented in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. Using data from the Premier Healthcare Database on 181,813... read more

Impact of Marijuana on Venous Thromboembolic Events

Impact of Marijuana on Venous Thromboembolic Events

Tetrahydrocannabinoids (THC) exposure increases the risk of TEC in patients with trauma. Early identification and treatment for TEC is required to improve outcomes in this high-risk subset of trauma patients. We performed... read more

COVID-19 Antibody Seropositivity Longevity Analysis

COVID-19 Antibody Seropositivity Longevity Analysis

Seropositivity of IgG antibodies to both SARS-CoV-2 S and N-proteins followed a linear trend reaching approximately 90% positivity at 21 days post-index. The rate of N-protein seropositivity declined at a sharper rate,... read more

COVID-19 Infection Induces Long-lived Bone Marrow Plasma Cells

COVID-19 Infection Induces Long-lived Bone Marrow Plasma Cells

Population scale sweeps of viral pathogens, such as SARS-CoV-2, require high intensity testing for effective management. Here, we describe "Systematic Parallel Analysis of RNA coupled to Sequencing for Covid-19 screening"... read more

Tox and Hound – Metal Hydrides

Tox and Hound – Metal Hydrides

We are left with four main scenarios in which arsine gas is produced and/or encountered: aqueous solutions of oxidized arsenic compounds in contact with metals metal arsenides in contact with water/moisture release... read more