New Infection Prevention Research Grant Award

New Infection Prevention Research Grant Award

The SHEA Education and Research Foundation (SHEAERF), in collaboration with the SHEA Research Committee, is seeking bright and dedicated early investigators within 5 years of completion of training (MPH, PhD, PharmD, or MD)... read more

Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization

Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization

Over 45% of sepsis patients had clinician-based encounters in the week prior to hospitalization with an increasing frequency of diagnoses for acute infection and antibiotic use in the outpatient setting. These presepsis encounters... read more

Probiotics Offer Powerful Protection Against Sepsis in Infants

Probiotics Offer Powerful Protection Against Sepsis in Infants

Sepsis can occur in just about anyone, including infants. Recent research shows feeding newborns probiotics (healthy bacteria) significantly lowers the child's risk of developing sepsis. The study involved infants in rural... read more

The Fallacy of Time-to-Intervention Studies

The Fallacy of Time-to-Intervention Studies

We are barraged by time-to-intervention studies (door-to-balloon time, time-to-antibiotics, door-to-needle, etc.). However, it must be kept in mind that these studies are purely correlational in design. Such studies cannot... read more

Trends and Patterns of Antibiotic Consumption in China

Trends and Patterns of Antibiotic Consumption in China

The consumption of antibiotics is a major driver in the development of antimicrobial resistance. This study aims to identify the trends and patterns of the total antibiotic consumption in China’s tertiary hospitals from... read more

Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants

Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants

In this randomized clinical trial that included 470 patients who were undergoing surgery for removal of orthopedic implants used for treatment of below-the-knee fractures, surgical site infection occurred in 12.9% of patients... read more

A New Combination of Antibiotic and Inhibitor

A New Combination of Antibiotic and Inhibitor

Intensivists have another antibiotic combination to treat severe infections caused by gram-negative bacteria with the FDA’s approval of Vabomere (meropenem, combined with the beta-lactamase inhibitor called vaborbactam).... read more

Diagnostic Importance of Pulmonary Interleukin-1β and Interleukin-8 in VAP

Diagnostic Importance of Pulmonary Interleukin-1β and Interleukin-8 in VAP

BALF IL-1β and IL-8 are amongst the strongest markers yet identified for accurately demarcating VAP within the larger population of patients with suspected VAP. These findings have potential implications for reduction in... read more

Dr. Paul Wischmeyer Brings Humanity To Medicine

Dr. Paul Wischmeyer Brings Humanity To Medicine

Dr. Paul Wischmeyer's journey to becoming an internationally-renowned critical care and perioperative nutrition researcher and clinician began at the age of 15 when a bout of strep throat and a prescription for antibiotics... read more

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more

Antibiotic Prescription Course

Antibiotic Prescription Course

In July, The BMJ published an analysis article called "The Antibiotic Course has had it’s day" - a provocative title that turned out the garner a lot of debate on our site. The article said that the convention for the length... read more

Workup, Management, and Critical Sequelae of Burn Injuries

Richard Iuorio, MD speaks with Laura Johnson, MD, and Jim Reilly, MD, about the workup, management, and critical sequelae of burn injuries. Using a fictional burn case as an example, Dr. Johnson talks about airway considerations,... read more

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction... read more

Prehospital Antibiotics in the Ambulance for Sepsis

Prehospital Antibiotics in the Ambulance for Sepsis

Emergency medical services (EMS) personnel have already made substantial contributions to improving care for patients with time-dependent illnesses, such as trauma and myocardial infarction. Patients with sepsis could also... read more