Tag: ARDS
Targeting Transfusion-Related Acute Lung Injury
We propose that the most promising therapeutic strategies to explore are interleukin-10 therapy, down-modulating C-reactive protein levels, targeting reactive oxygen species, or blocking the interleukin-8 receptors; all focused... read more
Lower ARDS Mortality at High-Volume Intensive Care Units
For patients with acute respiratory distress syndrome (ARDS), mortality is lower in high-volume intensive care units (ICUs), according to a study presented at the annual meeting of the American Thoracic Society. The researchers... read more
Early Application of APRV May Reduce the Duration of Mechanical Ventilation in ARDS
Compared with LTV, early application of airway pressure release ventilation (APRV) in patients with ARDS improved oxygenation and respiratory system compliance, decreased Pplat and reduced the duration of both mechanical... read more
Train Of Four Monitoring
A peripheral nerve stimulator, also called the "train of four", is used to assess nerve function in patients receiving neuromuscular blocking agents (AKA paralytic medications). It is commonly seen used in critical care... read more
High Frequency Percussive Ventilation Increases Alveolar Recruitment in Early ARDS
High frequency percussive ventilation (HFPV) combines diffusive (high frequency mini-bursts) and convective ventilation patterns. Benefits include enhanced oxygenation and hemodynamics, and alveolar recruitment, while providing... read more
Characteristics and Outcomes of ICU Survivors
A significant number of intensive care unit survivors evaluated 3 months after discharge had psychological, respiratory, motor, and socioeconomic problems; these findings highlight that strategies aimed to assist critically... read more
Six-month Outcome of Immunocompromised Severe ARDS Patients Rescued by ECMO
Recently diagnosed immunodeficiency is associated with a much better prognosis in ECMO-treated severe ARDS. However, low 6-month survival of our large cohort of immunocompromised patients supports restricting ECMO to patients... read more
Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation
Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more
Effect of Lung Recruitment and Titrated PEEP vs Low PEEP on Mortality in Patients with ARDS
In patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS), a strategy with lung recruitment and titrated Positive End-Expiratory Pressure (PEEP) compared with low PEEP increased 28-day all-cause mortality.... read more
Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium
Among patients with acute respiratory distress syndrome (ARDS), cisatracurium does not improve mortality versus vecuronium but is associated with improvements in other outcomes, according to a study published online in the... read more
Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe ARDS
Neuromuscular blockade alone does not cause hypothermia but allowed acute respiratory distress syndrome patients to be effectively cooled. Results support conducting a randomized clinical trial of hypothermia in acute respiratory... read more
Fifty Years of Research in ARDS
Mechanical ventilation (MV) is critical in the management of many patients with acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate... read more
The Future of Mechanical Ventilation
The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS) arise from two main causes: unphysiological increases of transpulmonary pressure and unphysiological increases/decreases of pleural... read more
Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency – Part II
This part II of the guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients is related to acute illnesses that may be complicated by CIRCI. We... read more
Predicting the Hemodynamic Response to Prone Positioning
Graphical models of physiology are heuristically appealing as they facilitate qualitative conclusions at the bedside of the critically ill. Historically, the Rahn diagram has portrayed the physiology of the lungs, chest wall... read more
The Hidden Faces of Sepsis, What Do They Tell Us?
Based on the patients' perspective Nutma sheds light on the hidden faces of sepsis, calling for more expertise on sepsis sequelae. She also offers recommendations to improve recovery and outcome. Sepsis really caught me by... read more
Implementation of a Goal-Directed Mechanical Ventilation Order Set Improves Compliance
Implementation of a Goal-Directed Mechanical Ventilation Order Set Driven by Respiratory Therapists Improves Compliance With Best Practices for Mechanical Ventilation. Data regarding best practices for ventilator management... read more
