Tag: ARDS
The World Day of the Critical Lung Event
On November 17th 2017, the first edition of "The World Day of the Critical Lung" will be held. It will be an online, global, free, bilingual (Spanish and English) participatory and non-profit event organized by the Pan American... read more
Gas Exchange in ARDS
Acute respiratory distress syndrome (ARDS) is characterized by severe impairment of gas exchange. Hypoxemia is mainly due to intrapulmonary shunt, whereas increased alveolar dead space explains the alteration of CO2 clearance.... read more
Understanding Patient Outcomes After ARDS
We identified four post-ARDS outcome subtypes that were predicted by sex, ethnicity, pre-ARDS smoking status and other baseline factors. These subtypes may help develop tailored rehabilitation strategies, including investigation... read more
4m-gait speed test reliable/valid physical function measure in ARDS survivors
The 4-m gait speed is a reliable, valid, and responsive measure of physical function in acute respiratory distress syndrome survivors. The estimated minimal important difference will facilitate sample size calculations for... read more
Steroids for severe CAP. Should I?
Steroids. I always have mixed feelings about them. It's a Love & Hate relationship inside my head. On one hand I cannot stand those who claim steroids are the critical care's Holy Grail. Steroids for sepsis, ARDS, trauma,... read more
Post-ICU Psychological Morbidity in Very Long ICU Stay Patients with ARDS and Delirium
Delirium was associated with memory impairment and PTSS-14 scores suggestive of PTSD, but not illness severity. 181 subjects were included. Illness severity did not correlate with delirium duration. On logistic regression,... read more
External validation of a biomarker and clinical prediction model for hospital mortality in ARDS
Mortality prediction in ARDS is important for prognostication and risk stratification. However, no prediction models have been independently validated. We validated a mortality prediction model for ARDS that includes age,... read more
Acute Lung Failure – Our Evolving Understanding of ARDS
Since Laennec described the gross pathology of idiopathic anasarca of the lungs in 1821, mortality due to the acute respiratory distress syndrome has been vastly reduced. Yet the poor subsequent condition of ARDS survivors... read more
Improving Long-Term Outcomes Research for ARF
Alison Turnbull, DVM, MPH, PhD discusses the heterogeneity in outcome measures in our field and the need for a Core Outcome Measurement Set (COMS) to standardize reporting of important outcomes. As part of the consensus process,... read more
External Validity of Electronic Sniffers for Automated Recognition of ARDS
Automated electronic sniffers may be useful for early detection of acute respiratory distress syndrome (ARDS) for institution of treatment or clinical trial screening. Published electronic sniffer algorithms for ARDS may... read more
Are We Creating Survivors or Victims in Critical Care?
Delivering targeted nutrition to improve outcomes. Over the last 10 years, we are proud of the fact we have finally begun to reduce in-hospital mortality following severe sepsis in some countries worldwide. Further, mortality... read more
Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration
Among comatose patients receiving mechanical ventilation, those without clinical, laboratory, or radiologic evidence of bacterial aspiration pneumonia did not require antibiotics. In those with suspected bacterial aspiration... read more
Aspirin therapy in patients with ARDS is associated with reduced ICU mortality
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome with high mortality and long-term morbidity. To date there is no effective pharmacological therapy. Aspirin therapy has recently been shown to reduce... read more
Effect of Noninvasive Ventilation Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With ARDS
Noninvasive ventilation (NIV) with a face mask is relatively ineffective at preventing endotracheal intubation in patients with acute respiratory distress syndrome (ARDS). Delivery of NIV with a helmet may be a superior strategy... read more
Sevoflurane for Sedation in Acute Respiratory Distress Syndrome. A Randomized Controlled Pilot Study
Sevoflurane improves gas exchange, and reduces alveolar edema and inflammation in preclinical studies of lung injury, but its therapeutic effects have never been investigated in acute respiratory distress syndrome (ARDS).... read more
Personalised Medicine in Intensive Care
The specialty of intensive care medicine grew out of the realisation that critically ill patients needed more attention and specialised treatment than could be provided on a general ward, and that many of these patients had... read more
Generalizable Biomarkers in Critical Care
The sequencing of the human genome and the subsequent availability of inexpensive, robust methods for "omics" profiling (e.g., genome-wide association studies, gene expression microarrays, and metabolomics) have... read more
