Validation and Clinical Implications of the IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia

These findings support the use of the IDSA/ATS minor criteria to predict hospital mortality and guide ICU admission in inpatients with Community-Acquired Pneumonia (CAP) who do not require emergency mechanical ventilation... read more

Validation and Clinical Implications of the IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia

Initial Inflammatory Profile in Community-acquired Pneumonia Depends on Time since Onset of Symptoms

Time since symptom onset modifies the systemic inflammatory profile at Community-acquired Pneumonia (CAP) diagnosis. This information has relevant clinical implications for management, and it should be taken into account... read more

Initial Inflammatory Profile in Community-acquired Pneumonia Depends on Time since Onset of Symptoms

Metabolic Profiles in Community-Acquired Pneumonia

This study demonstrates that serum metabolomics approaches based on the LC-MS/MS platform can be applied as a tool to reveal metabolic changes during CAP and establish a metabolite signature related to disease severity. The... read more

Metabolic Profiles in Community-Acquired Pneumonia

Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia

Recent studies suggest older patients hospitalized for community-acquired pneumonia are at risk for new-onset cognitive impairment. The characteristics of long-term cognitive impairment after pneumonia, however, have not... read more

Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Precision medicine in critical care is a key part of our present and future. However, many challenges limit its application for all patients in the ICU. Complex acute illness among patients with multi-morbidity, integrated... read more

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Community-acquired pneumonia related to intracellular pathogens

Community-acquired pneumonia (CAP) is associated with high rates of morbidity and mortality worldwide; the annual incidence of CAP among adults in Europe has ranged from 1.5 to 1.7 per 1000 population.... read more

Community-acquired pneumonia related to intracellular pathogens

Few ICU Patients with Pneumonia Tested for Virus Infections

Researchers investigated the clinical practices of testing for respiratory virus infections in intensive care unit (ICU) patients with suspected community-acquired pneumonia (CAP) or hospital-acquired pneumonia (HAP) and... read more

Few ICU Patients with Pneumonia Tested for Virus Infections