Neuroprotective Effects of the Glucagon-Like Peptide-1 Analog Exenatide After Out-of-Hospital Cardiac Arrest

Neuroprotective Effects of the Glucagon-Like Peptide-1 Analog Exenatide After Out-of-Hospital Cardiac Arrest

Acute administration of exenatide to comatose patients in the ICU after OHCA is feasible and safe. Exenatide did not reduce neuron-specific enolase levels and did not significantly improve a composite end point of death and... read more

The impact of extracerebral organ failure on outcome of patients after cardiac arrest

The impact of extracerebral organ failure on outcome of patients after cardiac arrest

In this multicenter cohort, extracerebral organ dysfunction was common in CA patients. Renal failure on admission was the only extracerebral organ dysfunction independently associated with higher ICU mortality.... read more

Should we treat pyrexia? And how do we do it?

Should we treat pyrexia? And how do we do it?

Pyrexia has long been thought of as a protective physiological response to help host defences, although this is now being challenged. Despite recent advances, it remains unclear whether pyrexia or the physiological response... read more

Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation

Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation

In recent years there have been many developments in post-resuscitation care. We have investigated trends in patient characteristics and outcome following admission to UK critical care units following cardiopulmonary resuscitation... read more

What did the ALPS trial results really show?

What did the ALPS trial results really show?

The trial pitted amiodarone against lidocaine with a saline control group for the termination of shock-resistant ventricular tachycardia and ventricular fibrillation... read more