More Than Just Acid: Navigating the Complexities of Lactate in Critical Care

Lactate is a vital marker in critical care, but its meaning is complex, reflecting an interplay of perfusion, metabolism, organ function, and stress. Clinicians must adopt a nuanced, multimodal approach to interpretation,... read more

The MAP-SEPS Protocol: A New Frontier in Detecting Early Sepsis by Targeting Microcirculation

The MAP-SEPS trial is a prospective observational study designed to determine if a comprehensive, multimodal approach to peripheral perfusion monitoring can improve the early detection of sepsis and organ failure in critically... read more

Fluid Boluses May Improve CRT

Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to further explore... read more