Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle

Critically ill patients managed with the Awakening and Breathing Coordination, Delirium monitoring/management, and Early exercise/mobility bundle spent three more days breathing without assistance, experienced less delirium,... read more

Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle

A Systematic Review of Risk Factors for Sleep Disruption in Critically Ill Adults

This systematic review summarizes all premorbid, illness-related, and ICU-related factors associated with sleep disruption in the ICU. These findings will inform sleep promotion efforts in the ICU and guide further research... read more

A Systematic Review of Risk Factors for Sleep Disruption in Critically Ill Adults

The Pandemic Is a Perfect Storm for ICU Delirium

Spending time in the ICU, especially for anyone with COVID-19, is a dangerous, physically taxing experience: Only the most seriously ill patients land in intensive care, where many undergo a number of complex medical treatments... read more

The Pandemic Is a Perfect Storm for ICU Delirium

Restoring Humanity In The ICU During COVID-19

Machines, tubes, wires, drugs, isolation, confusion... how can we protect the dignity and sanity of our patients when they're at their most vulnerable? Dr. Wes Ely is a Vanderbilt professor and critical care doc who can... read more

Restoring Humanity In The ICU During COVID-19

ICU Doctors Already Know How to Get COVID-19 Patients Off Ventilators Faster

The coronavirus pandemic is instilling chaos that is shaking the world. When intensive care units are running out of ventilators and essential medications, and some 95,000 people die in a matter of a few months, society panics... read more

ICU Doctors Already Know How to Get COVID-19 Patients Off Ventilators Faster

Decrease Delirium in Older ICU Adults Using Music

Researchers from the Regenstrief Institute and Mayo Clinic are leading the first study to test whether exposure to music can decrease delirium in older adults who are receiving mechanical ventilation in the Intensive Care... read more

Decrease Delirium in Older ICU Adults Using Music

ICU Risk Factors and Outcomes for Each Delirium Subtype

Although included studies reported on many subtype-specific risk factors (hypoactive, hyperactive) and outcomes, heterogeneity in reporting and methodological quality limited the generalizability of the results and the evidence... read more

ICU Risk Factors and Outcomes for Each Delirium Subtype

Dancing with Elephants: Mindfulness Training For Those Living With Dementia, Chronic Illness or an Aging Brain

Author Jarem Sawatsky saw the countless guides out there for those caring for the ill and healing the curable, but when he was diagnosed with Huntington's Disease he found there was nothing for those living with incurable... read more

Dancing with Elephants: Mindfulness Training For Those Living With Dementia, Chronic Illness or an Aging Brain

The ABCDE Bundle Associated with Significant Reductions in Duration of Mechanical Ventilation

The focus on long-term consequences of critical illness has intensified with increasing ICU utilization and survivorship. Post Intensive Care Syndrome (PICS) is increasingly recognized and has profound and long-lasting negative... read more

The ABCDE Bundle Associated with Significant Reductions in Duration of Mechanical Ventilation

Leading EHR System Adopts Bundle to Prevent ICU Delirium

Seminal studies at Vanderbilt University Medical Center over the past two decades by pulmonary and critical care specialist Wes Ely, M.D. and colleagues have spurred ICU delirium research, and the resulting body of evidence... read more

Leading EHR System Adopts Bundle to Prevent ICU Delirium

Impact of Natural Light Exposure on Delirium Burden in Adult Patients Receiving Invasive Mechanical Ventilation in the ICU

Admission to a single room with potential exposure to natural light via windows was not associated with reduced delirium burden, as compared to admission to a single room without windows. However, natural light exposure was... read more

Impact of Natural Light Exposure on Delirium Burden in Adult Patients Receiving Invasive Mechanical Ventilation in the ICU

Incidence of Dexmedetomidine Withdrawal in Adult Critically Ill Patients

The majority of patients in our study demonstrated signs that may be indicative of dexmedetomidine withdrawal. Peak and cumulative daily dexmedetomidine dose, rather than duration of therapy, may be associated with a higher... read more

Incidence of Dexmedetomidine Withdrawal in Adult Critically Ill Patients

Delirium is Prevalent in Older Hospital Inpatients and Associated with Adverse Outcomes

Delirium is prevalent in older adults in UK hospitals but remains under-recognised. Frailty is strongly associated with the development of delirium, but delirium is less likely to be recognised in frail patients. The... read more

Delirium is Prevalent in Older Hospital Inpatients and Associated with Adverse Outcomes

Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium

In the primary analysis, limiting the level of sedation provided no significant benefit in reducing incident delirium. However, in a pre-specified subgroup analysis, lighter sedation levels benefitted reducing postoperative... read more

Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium

PICU Up! A Multicomponent Early Mobility Intervention for Critically Ill Children

Pediatric intensive units traditionally have had a culture where critically ill children are intubated and mechanically ventilated, immobilized, and highly sedated. This practice is primarily driven by a focus on safety... read more

PICU Up! A Multicomponent Early Mobility Intervention for Critically Ill Children

Effect of Flexible Family Visitation on Delirium Among Patients in the ICU

In this cluster-crossover randomized clinical trial that involved 1,685 patients in the intensive care unit (ICU), the incidence of delirium was 18.9% in the flexible family visitation group compared with 20.1% in the standard... read more

Effect of Flexible Family Visitation on Delirium Among Patients in the ICU

How To Prevent Brain-Sapping Delirium In The ICU

After an overwhelming infection sent O'Burke into five-organ failure, he also developed ICU delirium, perhaps related to heavy sedation. An ICU protocol developed at Vanderbilt University Medical Center found that getting... read more

How To Prevent Brain-Sapping Delirium In The ICU