Tag: diagnosis
Diagnosis of Sepsis from a Drop of Blood by Measurement of Spontaneous Neutrophil Motility in a Microfluidic Assay
Current methods for the diagnosis of sepsis have insufficient precision, causing regular misdiagnoses. Microbiological tests can help to diagnose sepsis, but are usually too slow to have an impact on timely clinical decision-making.... read more
Reducing contamination rates in urine samples
Contamination is thought to be a significant problem. Depending on which study you look at, the rates of urine contamination can be 17% or upwards. The standard method of midstream urine collection is for the healthcare professional... read more
Severe Sepsis Care in the Emergency Department
Drs. John C. Perkins and Michael E. Winters have assembled an expert team of authors on the topic of Sepsis in the Emergency Department. Article topics include: Defining and Diagnosing Sepsis; Appropriate Antibiotic Therapy;... read more
Fluid, Electrolyte and Acid-Base Physiology
With a strong focus on problem solving and clinical decision making, Fluid, Electrolyte, and Acid-Base Physiology is your comprehensive, go-to guide on the diagnosis and management of fluid, electrolytes, and acid-base disorders.... read more
Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis
Many sepsis survivors develop chronic critical illness (CCI) and are assumed to be immunosuppressed, but there is limited clinical evidence to support this. We sought to determine whether the incidence of secondary infections... read more
The Right Tool for the Right Patient
Resuscitative TEE in the diagnosis of massive PE in the ED. We have multiple tools in the ed that allow us to assess patients rapidly. But of course, you must use the right tool for the patient. transthoracic echo (TTE) can... read more
The long sepsis journey in low- and middle-income countries begins with a first step… but on which road?
Infection and sepsis are among the most frequent acute medical conditions worldwide and result in approximately eight million premature deaths each year, most of which occur in low and lower-middle income countries (LMICs).... read more
The Randomized Educational ARDS Diagnosis Study
Radiographic criteria for acute respiratory distress syndrome have been criticized for poor reliability. Our objective was to test an educational intervention to improve the radiographic identification of acute respiratory... read more
Research Aims to Fine-Tune Sepsis Diagnosis
Work designed to improve diagnosis of one of the leading causes of death in children is under way in Brisbane, led by a University of Queensland researcher. Mater Research Institute-UQ Associate Professor Luregn Schlapbach... read more
Distributions and Behavior of Vital Signs in Critically Ill Children by Admission Diagnosis
This is the first study reporting distributions of continuously measured physiologic variables and trends in their behavior according to admission diagnosis in critically ill children. Differences detected between and within... read more
The Sound of Air: Point-of-Care Lung Ultrasound in Perioperative Medicine
Lung ultrasound (LUS) has emerged as an effective and accurate goal-directed diagnostic tool that can be applied in real time for the bedside assessment of patients with respiratory symptoms and signs. Lung ultrasound has... read more
Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults
One in three acutely ill hospitalized older adults who suffered hypo-active or mixed delirium died in the hospital. Clinicians should be aware that hypo-active symptoms of delirium, whether shown exclusively or in alternation... read more
Differential Diagnosis Between Newly Diagnosed Asthma and COPD Using EBC Metabolomics
Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases with high pathological burden and healthcare costs. In the outpatient clinical practice, an accurate differential diagnosis is often very... read more
Vascular Access in Critically Ill Pediatric Patients With Obesity
Severe obesity is associated with decreased overall likelihood of placement of a vascular access device but increased likelihood of peripherally inserted central catheter placement and of device-related complications. Patients... read more
Machine Learning Model Predicts Sepsis in ICU Patients 12 Hours Before Diagnosis
A machine learning model accurately predicted the onset of sepsis in ICU patients four to 12 hours prior to clinical recognition in a recent study. The observational cohort study used data from more than 31,000 admissions... read more
Six-month Outcome of Immunocompromised Severe ARDS Patients Rescued by ECMO
Recently diagnosed immunodeficiency is associated with a much better prognosis in ECMO-treated severe ARDS. However, low 6-month survival of our large cohort of immunocompromised patients supports restricting ECMO to patients... read more
The role of serum amyloid A staining of granulomatous tissues for the diagnosis of sarcoidosis
Previous studies demonstrated that SAA staining of sarcoidosis granulomas was qualitatively and quantitatively different from other granulomatous diseases. These data suggest that positive SAA staining of granulomatous tissue... read more