New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke

New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke

Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.... read more

Could a Metabolic Switch Explain Inflammation in Lupus Patients?

Could a Metabolic Switch Explain Inflammation in Lupus Patients?

Researchers discovered a new mechanism linking specific classes of immune cells and metabolism, a finding that may explain why patients with lupus are incapable of controlling the inflammatory responses that ultimately lead... read more

Simultaneous assessment of the synthesis rate and transcapillary escape rate of albumin in inflammation and surgery

Simultaneous assessment of the synthesis rate and transcapillary escape rate of albumin in inflammation and surgery

Single measurements of the synthesis rate and/or transcapillary escape rate of albumin obviously cannot explain the plasma level of albumin or the changes seen in plasma albumin concentration.... read more

Increased global, subcutaneous inflammation in psoriasis

Increased global, subcutaneous inflammation in psoriasis

Psoriasis patients have increased global arterial inflammation and subcutaneous inflammation, according to a study published online Oct. 27 in the British Journal of Dermatology.... read more

Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before

Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before

Four innovative studies exploring ways to reduce complications related to heart surgery or minimize patient mortality due to risks associated with low blood pressure and surgery.... read more

Immune system of African Americans responds more strongly to bacterial infection, and it is partly genetic

Immune system of African Americans responds more strongly to bacterial infection, and it is partly genetic

A Canada-US study has demonstrated that Americans of African descent have a stronger immune response to infection compared to Americans of European descent.... read more

Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis

Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis

The outcome of treating two patients with FMT indicates that restoration of the intestinal microbiota barrier can alleviate the infection and modulate the immune response.... read more

Neuropilin 2 deficiency linked to inflammation-induced edema

Neuropilin 2 deficiency linked to inflammation-induced edema

A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more

Researchers identify genes that may cause gum disease

Researchers identify genes that may cause gum disease

Columbia University scientists say they have identified 41 master regulator genes that may cause gum disease in a first-of-its-kind study.... read more

Should we treat pyrexia? And how do we do it?

Should we treat pyrexia? And how do we do it?

Pyrexia has long been thought of as a protective physiological response to help host defences, although this is now being challenged. Despite recent advances, it remains unclear whether pyrexia or the physiological response... read more

Omega-3 could help prevent environmentally induced lupus

Omega-3 could help prevent environmentally induced lupus

A new study suggests that docosahexaenoic acid - a type of omega-3 present in fish oil and dietary supplements - has the potential to prevent lupus, after finding the fatty acid blocked a known trigger of the disease.... read more

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are... read more

Belgian scientists discover missing link in septic shock

Belgian scientists discover missing link in septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection.... read more

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

A research team from the University of Oklahoma Health Sciences Center, led by Madeleine Cunningham, Ph.D., in conjunction with the National Institute of Mental Health, has developed the first-of-its-kind biomarker test to... read more