Epidemiology of Invasive Pulmonary Aspergillosis Among COVID-19 Intubated Patients

We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence seems to change the natural history of disease. A total of 108 patients were enrolled. Prospective, multicentre study... read more

Epidemiology of Invasive Pulmonary Aspergillosis Among COVID-19 Intubated Patients

Utility of RV Remodeling Over Risk Stratification in COVID-19

This study contributes to the growing body of literature illustrating the adverse prognostic implications of RV dilation and dysfunction in the setting of severe COVID-19. Mechanistic explanations for RV failure in this population... read more

Utility of RV Remodeling Over Risk Stratification in COVID-19

Some Signs of Recovery From Severe COVID-19 Lung Damage

In two early studies, researchers said some patients showed signs of healing just weeks after leaving the hospital. Lingering shortness of breath and diminished stamina have dogged many COVID patients whose lungs were... read more

Some Signs of Recovery From Severe COVID-19 Lung Damage

Outcomes of Patients Requiring Prolonged Acute vs. Short-Term Mechanical Ventilation

Over one-third of all hospitalized patients on mechanical ventilation require it for greater than or equal to 4 days. Prolonged acute mechanical ventilation patients exhibit a higher burden of both chronic and acute illness... read more

Outcomes of Patients Requiring Prolonged Acute vs. Short-Term Mechanical Ventilation

Monitoring of the Adult Patient on VA ECMO

Venoarterial extracorporeal membrane oxygenation (VA ECMO), a form of mechanical circulatory support, had its origins in the operating room as cardiopulmonary bypass and has evolved for use in the intensive care unit and... read more

Monitoring of the Adult Patient on VA ECMO

Efficacy and Safety of a Paired Sedation and Ventilator Weaning

The purpose of this study is to determine the impact of a new RN/RRT (Registered Nurse/Registered Respiratory Therapist) directed 2-step protocol to wean patients off of a ventilator. This protocol involves daily attempts... read more

Efficacy and Safety of a Paired Sedation and Ventilator Weaning

Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis

The objective of this study was to clarify whether early intervention by arterial embolization reduced mortality in mechanically ventilated patients with hemoptysis. The results show that early intervention by arterial... read more

Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis

Standardized Perioperative Feeding Protocol Improves Outcomes

An aggressive, but safe, perioperative feeding protocol implemented in a homogenous low-risk neonatal cardiac surgical population improves feeding outcomes, including increased weight gain, as well as decreased postoperative... read more

Standardized Perioperative Feeding Protocol Improves Outcomes

How Severe COVID-19 Infection is Changing ARDS Management

The COVID-19 pandemic has provided many intensivists (and some non-intensivists) several years' worth of severe ARDS management experience over the course of just a few months. While the challenges have, in places, been extreme,... read more

How Severe COVID-19 Infection is Changing ARDS Management

Outcomes of COVID-19 Patients Admitted to Australian ICUs During Early Pandemic Phase

During the early phase of the pandemic in Australia, patients admitted to ICU with COVID-19 had lower mortality and longer length of stay than reported from other regions. These findings reinforce the importance of ensuring... read more

Outcomes of COVID-19 Patients Admitted to Australian ICUs During Early Pandemic Phase

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

Nasotracheal intubation is used in a minority of U.S. PICUs and mainly among young cardiac patients. Nasotracheal intubation is associated with a lower rate of unplanned extubations in this patient population. Future... read more

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

LV Overloading Identified by Critical Care Echocardiography is Key in Weaning‑induced Pulmonary Edema

Spontaneous breathing trial (SBT) failure due to WIPO appears related to overloaded LV, including the worsening or development of mitral regurgitation, associated with excessive accumulated fluid balance. SBT-induced central... read more

LV Overloading Identified by Critical Care Echocardiography is Key in Weaning‑induced Pulmonary Edema

Steroids Confirmed to Help Severely Ill COVID-19 Patients

In patients hospitalized with COVID-19, the use of dexamethasone resulted in lower 28-day mortality among those who were receiving either invasive mechanical ventilation or oxygen alone at randomization but not among those... read more

Steroids Confirmed to Help Severely Ill COVID-19 Patients

Mechanical Ventilation: Physiology and Practice

Mechanical ventilation is an essential life-sustaining therapy for many critically-ill patients. As technology has evolved, clinicians have been presented with an increasing number of ventilator options as well as an ever-expanding... read more

Mechanical Ventilation: Physiology and Practice

Prone Positioning in Non-intubated Patients with COVID-19

As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more

Prone Positioning in Non-intubated Patients with COVID-19

ICU Trends for Patients with COVID-19 in England, Wales and Northern Ireland

Observed trends suggest opposing effects of ICU strain and clinical learning. Further investigation is needed to identify modifiable system factors that could alleviate strain in future epidemics and changes in clinical practice... read more

ICU Trends for Patients with COVID-19 in England, Wales and Northern Ireland

Efficacy and Safety of a Paired Sedation and Ventilator Weaning Protocol in ICU

Approaches to removal of sedation and mechanical ventilation for critically ill patients vary widely. Our aim was to assess a protocol that paired spontaneous awakening trials (SATs)—ie, daily interruption of sedatives—with... read more

Efficacy and Safety of a Paired Sedation and Ventilator Weaning Protocol in ICU

Automated vs. Conventional Ventilation in the ICU

Automated ventilation (AV) appears to reduce the incidence and severity of blood oxygen desaturation during daily nursing procedures (DNPs) in comparison to Conventional Ventilation (CV). Of the 265 included patients,... read more

Automated vs. Conventional Ventilation in the ICU

ICU Doctor Creates App to Help Patients on Ventilators Communicate Faster

ICU Doctor Chandar Abboy and his partner came up with a way to give a voice to the voiceless. The app called “Yo Doc” allows patients on ventilators to better communicate their needs and feelings. Dr. Abboy says this... read more

ICU Doctor Creates App to Help Patients on Ventilators Communicate Faster

Association Between Anxiety and New Organ Failure, Independently of Critical Illness Severity and Respiratory Status

Moderate to severe anxiety at ICU admission is associated with early occurrence of new organ failure in critically ill patients, independently of respiratory status and severity of critical illness. The causality link could... read more

Association Between Anxiety and New Organ Failure, Independently of Critical Illness Severity and Respiratory Status

COVID-19 Drug Treatments: Living Systematic Review and Network Meta-analysis

Glucocorticoids probably reduce mortality and mechanical ventilation in patients with COVID-19 compared with standard care. The effectiveness of most interventions is uncertain because most of the randomised controlled trials... read more

COVID-19 Drug Treatments: Living Systematic Review and Network Meta-analysis