Mechanical Ventilation: Which Patients Benefit from High PEEP?

Among patients with hypoxaemia after cardiac surgery, the use of an intensive alveolar recruitment strategy compared with a moderate recruitment strategy resulted in less severe pulmonary complications during the hospital... read more

Mechanical Ventilation: Which Patients Benefit from High PEEP?

Clinical review: The ABC of weaning failure

About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing... read more

Clinical review: The ABC of weaning failure

Vitamin D and outcomes in adult critically ill patients

In critically ill patients, vitamin D administration might be associated with a reduction in mortality without significant adverse events. A large multicenter randomized trial should conclusively confirm these findings. Seven... read more

An Educational Intervention Optimizes the Use of Arterial Blood Gas Determinations Across ICUs

The large scale implementation of guidelines for ABG use reduced the number of inappropriately ordered ABG determinations over seven different multidisciplinary ICUs, without negatively impacting patient care. We saw a reduction... read more

An Educational Intervention Optimizes the Use of Arterial Blood Gas Determinations Across ICUs

Delirium: Thinking Clearly About a Foggy Issue

Benzodiazepines are one of the leading causes of delirium. These drugs are already falling out of favor in critical care settings for other reasons; they are not easily titratable, and research suggests they can prolong a... read more

Delirium: Thinking Clearly About a Foggy Issue

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

In this multicenter study in 1202 American Society of Anesthesiologists physical status 3 patients undergoing noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mechanical ventilation, at least... read more

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

Liberation from Mechanical Ventilation in Critically Ill Adults

Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. The panel provides recommendations... read more

Liberation from Mechanical Ventilation in Critically Ill Adults

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

Ten trials met the inclusion criteria for this review (n = 1658 participants). We found five trials to be at low risk of bias and five to be at moderate risk of bias.... read more

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

New Guidelines for Discontinuing Mechanical Ventilation in the ICU

The goal of the guidelines is to help physicians and other healthcare professionals determine when patients with acute respiratory failure can breathe on their own and to provide clinical advice that may increase the chances... read more

New Guidelines for Discontinuing Mechanical Ventilation in the ICU

Communication App Helps Patients Voice Their Needs

An innovative tablet-based application offers intubated and ventilated intensive care unit (ICU) patients a way to converse with their medical staff.... read more

Communication App Helps Patients Voice Their Needs