Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction... read more

Are contact isolation precautions (CP) necessary when caring for patients infected or colonized with endemic MRSA or VRE?

Are contact isolation precautions (CP) necessary when caring for patients infected or colonized with endemic MRSA or VRE?

Researchers from the University of Nebraska Medical Center Division of Infectious Diseases and Nebraska Medicine Department of Infection Control and Epidemiology recently published results from a two-year observational study... read more

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause metastatic or... read more

Contact Precautions for Endemic MRSA and VRE

Contact Precautions for Endemic MRSA and VRE

Physical barriers have been used to prevent infectious diseases dating back to leather gloves and coats used during the Black Death in medieval Europe. In the United States, isolation of persons with infections coincided... read more

A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses

A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses

Uncomplicated skin abscesses are common, yet the appropriate management of the condition in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA) is unclear. As compared with incision and drainage... read more

Empirical MRSA Coverage for Nonpurulent Cellulitis

Empirical MRSA Coverage for Nonpurulent Cellulitis

Cellulitis is an infection of the deep dermis and subcutaneous tissue, manifesting as expanding erythema, edema, and warmth of the skin. In most instances of cellulitis, the causative microorganism cannot be definitively... read more

Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound

Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound

Cationic antimicrobial peptides are multifunctional molecules that have a high potential as therapeutic agents. We have identified a histone H1-derived peptide from the Komodo dragon (Varanus komodoensis), called VK25. Using... read more

Study shows brute force antibiotics can overcome resistance

Study shows brute force antibiotics can overcome resistance

Researchers at the University College London have developed a new method that may overcome antibiotic resistance in bacterial cells. The team used sensitive equipment to measure the mechanical forces that four different antibiotics,... read more

Tackling Antimicrobial Resistance

Tackling Antimicrobial Resistance

Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are... read more

Outsourced Hospital Cleaning linked to MRSA

Outsourced Hospital Cleaning linked to MRSA

Analysis of English NHS hospitals suggests that employing private as opposed to in-house cleaners is a false economy. While it may reduce costs, it could also raise risk of infection by methicillin-resistant Staphylococcus... read more

Unnecessary Antibiotics Still Prescribed for Community-Acquired Pneumonia Due to Difficulties Identifying Resistant Strains

Unnecessary Antibiotics Still Prescribed for Community-Acquired Pneumonia Due to Difficulties Identifying Resistant Strains

Unnecessary Prescription of Antibiotics Still Prevalent Due to Difficulties in Identifying Antibiotic-Resistant Staphylococcus aureus Community-acquired Pneumonia. Researchers examined the true prevalence of methicillin (antibiotic)-resistant... read more

Antibiotics: resist the resistance

Antibiotics: resist the resistance

European Pharmaceutical Review caught up with Destiny Pharma’s CEO, Dr Love, for an interview about the threat of bacterial resistance to antibiotics...... read more