Mechanical Ventilation for the ICU Resident: A Concept Based Approach

This book is written primarily with the intent of helping medical residents understand the basics of mechanical ventilation. It is meant to be read during a one-month rotation in the ICU. It is a compilation of concepts... read more

Mechanical Ventilation for the ICU Resident: A Concept Based Approach

Clinical strategies for implementing lung and diaphragm-protective ventilation

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm develops atrophy as a consequence of low... read more

Clinical strategies for implementing lung and diaphragm-protective ventilation

Bedside Voluntary and Evoked Forces Evaluation in ICU Patients

Around one third of intensive care unit (ICU) patients will develop severe neuromuscular alterations, known as intensive care unit-acquired weakness (ICUAW), during their stay. The diagnosis of ICUAW is difficult and often... read more

Bedside Voluntary and Evoked Forces Evaluation in ICU Patients

5 Year Impact of ICU-acquired Neuromuscular Complications

ICU-acquired neuromuscular complications may impact 5-year morbidity and mortality. MRC sum score, even if slightly reduced, may affect long-term mortality, strength, functional capacity and physical function, whereas abnormal... read more

5 Year Impact of ICU-acquired Neuromuscular Complications

Urgent Intubation without Neuromuscular Blocking Agents and the Risk of Tracheostomy

Neuromuscular blocking agents play a significant role in improving the success rate for urgent intubation, although there is limited evidence about the effect on subsequent outcomes, such as the incidence of tracheostomy.... read more

Urgent Intubation without Neuromuscular Blocking Agents and the Risk of Tracheostomy

Effects of Neuromuscular Block Reversal with Sugammadex vs. Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery

No differences found in pulmonary function in patients reversed with sugammadex or neostigmine in a high-risk population. 126 patients were included in the main analysis. In the neostigmine group (n = 64), mean (95%... read more

Effects of Neuromuscular Block Reversal with Sugammadex vs. Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery

Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient

Dr. Todd Fraser, MD, speaks with Michael J. Murray, MD, PhD, FCCM, FCCP, about the article, "Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient," published in Critical Care... read more