Noninvasive Ventilation in Hypercapnic COPD

Noninvasive Ventilation in Hypercapnic COPD

Recently, Murphy and colleagues reported findings from a clinical trial designed to evaluate the effect of home noninvasive ventilation (NIV) with oxygen on time to readmission or death in patients with persistent hypercapnia... read more

Inside the lives of America’s last iron lung patients

Inside the lives of America’s last iron lung patients

Long after the polio vaccine stemmed the disease that once infected thousands of people, a handful of U.S. polio survivors still rely on decades-old iron lung machines to stay alive-and must overcome increasing obstacles... read more

Clinical Review: Paracetamol in fever in critically ill patients

Clinical Review: Paracetamol in fever in critically ill patients

Paracetamol is a synthetic, nonopioid, centrally acting analgesic and antipyretic drug. Its antipyretic effect occurres because it inhibits cyclooxygenase-3 and the prostaglandin synthesis.... read more

Oxygen Therapy in Suspected Acute Myocardial Infarction

Oxygen Therapy in Suspected Acute Myocardial Infarction

Routine use of supplemental oxygen in patients with suspected myocardial infarction who did not have hypoxemia was not found to reduce 1-year all-cause mortality. A total of 6629 patients were enrolled. The median duration... read more

Avoiding Intubation

Avoiding Intubation

Review the basic principles and physiology of Non-Invasive Ventilation and High-Flow Oxygen Systems. Critical Care Summit talk by William Bender, MD, Assistant Professor of Pulmonary and Critical Care Emory University School... read more

Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation

Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation

In this randomized clinical trial of 116 patients, the addition of home noninvasive ventilation significantly prolonged time to readmission or death from 1.4 months to 4.3 months. Among patients with persistent hypercapnia... read more

Physiological Effects of Chronic Hypoxia

Physiological Effects of Chronic Hypoxia

This review examines an array of physiological responses to low cellular oxygen tensions and discusses the effect of increasing oxygen tensions, through oxygen conditioning, on such responses.... read more

BTS Guideline for oxygen use in healthcare and emergency settings

BTS Guideline for oxygen use in healthcare and emergency settings

The updated guidance is based on new evidence about how effective prescribing and delivery of emergency oxygen for patients can both improve health and save lives. The 2015 emergency oxygen audit report provides information... read more

A Breakthrough Oxygen Therapy May Be Able to Reverse Brain Damage

A Breakthrough Oxygen Therapy May Be Able to Reverse Brain Damage

New research shows that low oxygen therapy is able to eliminate brain lesions developed from mitochondrial dysfunction in mice. Eventually, hypoxia therapy could be used to treat people with similar disorders and maybe even... read more

Addition of vitamin B12 to exercise training improves cycle ergometer endurance in advanced COPD patients

Addition of vitamin B12 to exercise training improves cycle ergometer endurance in advanced COPD patients

Vitamin B12 is essential in the homocysteine, mitochondrial, muscle and hematopoietic metabolisms, and its effects on exercise tolerance and kinetics adjustments of oxygen consumption (V'O2p) in rest-to-exercise transition... read more

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

In this multicenter study in 1202 American Society of Anesthesiologists physical status 3 patients undergoing noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mechanical ventilation, at least... read more

Portable Imaging Device Assesses Tissue Oxygenation

Portable Imaging Device Assesses Tissue Oxygenation

A handheld, battery operated diagnostic imaging device measures oxygen saturation (O2Sat) and other measures in superficial tissues for patients with potential circulatory compromise. The HyperView is intended for use by... read more

Pre-Op Screen: What Does A Pulse Oximeter Tell Us?

Pre-Op Screen: What Does A Pulse Oximeter Tell Us?

Routinely utilized in ICUs, operating rooms, and telemetry floors, the pulse oximeter ("pulse ox") is perhaps the single greatest monitoring advancement in the modern medical era. It relies on the fact that oxyhemoglobin... read more

COPD and Life Expectancy

COPD and Life Expectancy

COPD is the third leading cause of death after heart disease and cancer. Chronic obstructive pulmonary disease is a term for many health conditions that affect a person's lungs on a chronic basis. The condition causes... read more