Teaching the Principles of Pediatric Critical Care to Non-Intensivists in Resource Limited Settings

Teaching the Principles of Pediatric Critical Care to Non-Intensivists in Resource Limited Settings

It is a dismal reality of global health that the vast majority of critically ill or injured children are found in regions of the world least equipped to care for them. Most of these severely ill or injured children are cared... read more

Oliguria and AKI in Critically Ill Children

Oliguria and AKI in Critically Ill Children

Nearly one in five critically ill children with acute kidney injury (AKI) do not experience increase in serum creatinine. These acute kidney injury events, which are only identified by urine output criteria, are associated... read more

A Prospective Investigation of Interleukin-8 Levels in Pediatric ARF and ARDS

A Prospective Investigation of Interleukin-8 Levels in Pediatric ARF and ARDS

The association of plasma interleukin-8 (IL-8), or IL-8 genetic variants, with pediatric acute respiratory distress syndrome (PARDS) in children with acute respiratory failure (ARF) at risk for PARDS has not been examined.... read more

Neurally adjusted ventilatory assist decreases work of breathing during non-invasive ventilation in infants with severe bronchiolitis

Neurally adjusted ventilatory assist decreases work of breathing during non-invasive ventilation in infants with severe bronchiolitis

In this physiological study, we report an improvement of respiratory unloading by adding a second level of pressure with NAVA in infants with severe bronchiolitis. WOB decreased immediately after switching to NAVA, as reported... read more

The Effects of Family Functioning on the Development of Posttraumatic Stress in Children and Their Parents Following Admission to the PICU

The Effects of Family Functioning on the Development of Posttraumatic Stress in Children and Their Parents Following Admission to the PICU

Both children and parents have alarmingly high rates of acute stress and posttraumatic stress following the child's PICU admission. Although family function did not emerge as a predictor in this study, further understanding... read more

Neutrophil Extracellular Traps (NETs) Exacerbate Severity of Infant Sepsis

Neutrophil Extracellular Traps (NETs) Exacerbate Severity of Infant Sepsis

Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. This study reveals a hitherto... read more

Tracheal Intubation Practice and Safety Across International PICUs

Tracheal Intubation Practice and Safety Across International PICUs

There were both similarities and differences in tracheal intubation practice and outcomes across international PICUs. Fewer adverse tracheal intubation–associated events were reported from International versus North American... read more

Ethical Dilemmas in Pediatrics

Ethical Dilemmas in Pediatrics

Children in precarious health present particular problems for healthcare professionals because of their intimate relation to their family, and because of the family's need to provide major long-term source of support and... read more

Expanding the Differential for Hypotension in the Pediatric Patient

Expanding the Differential for Hypotension in the Pediatric Patient

As many ED practitioners are aware, food allergies are common in the first 2 years of life, with a prevalence cited between 1-10% of the population. Most food allergies are IgE-mediated hypersensitivity reactions. Food protein-induced... read more

The PICU Handbook

The PICU Handbook

The PICU Handbook is a unique, portable compilation of the information essential for residents and fellows to successfully navigate the modern Level 1 and Level 2 pediatric intensive care unit (PICU). Enhanced by numerous... read more

Evaluating the Need for Pediatric Procedural Sedation Training in Pediatric Critical Care Medicine Fellowship

Evaluating the Need for Pediatric Procedural Sedation Training in Pediatric Critical Care Medicine Fellowship

Pediatric procedural sedation lacks a clearly defined training pathway. Most fellows find pediatric procedural sedation a valuable skill set. We propose that all Pediatric Critical Care Medicine fellows receive training that... read more

Management of Pediatric Severe Traumatic Brain Injury

Management of Pediatric Severe Traumatic Brain Injury

This article provides an algorithm of clinical practice for the bedside practitioner based on the available evidence, treatment protocols described in the articles included in the 2019 guidelines, and consensus that reflects... read more

Tranexamic Acid For Isolated Penetrating Head Trauma

Tranexamic Acid For Isolated Penetrating Head Trauma

An aeromedical crew was dispatched to a local emergency department to transport a fourteen year-old female with self-inflicted gunshot wound to the head to a tertiary pediatric trauma hospital. The patient was previously... read more

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Small size central vascular catheters display optimal rheologic performances in terms of pressures and flows particularly when the renal replacement therapy (RRT) device is equipped with pumps proportional to central vascular... read more

Guidelines for the Management of Pediatric Severe Traumatic Brain Injury

Guidelines for the Management of Pediatric Severe Traumatic Brain Injury

Update of the Brain Trauma Foundation Guidelines, Third Edition. Severe Traumatic Brain Injury in Infants, Children, and Adolescents in 2019: Some Overdue Progress, Many Remaining Questions, and Exciting Ongoing Work in the... read more

RBC Transfusions Are Associated With Prolonged Mechanical Ventilation in Pediatric ARDS

RBC Transfusions Are Associated With Prolonged Mechanical Ventilation in Pediatric ARDS

RBC transfusion was independently associated with longer duration of mechanical ventilation in pediatric acute respiratory distress syndrome. Hemoglobin transfusion thresholds should be tested specifically within pediatric... read more

Muscle Atrophy in Mechanically-ventilated Critically Ill Children

Muscle Atrophy in Mechanically-ventilated Critically Ill Children

In children receiving invasive mechanical ventilation, diaphragm and other skeletal muscle atrophy is common and rapid. Increasing age and TBI may increase severity of limb muscle atrophy. Prospective studies are required... read more